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The Absence of CYP3A53 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects

PloS one, 2015-08, Vol.10 (8), p.e0136141-e0136141

2015

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Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92

2010

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Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.2087

2009

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Trends in Tramadol: Pharmacology, Metabolism, and Misuse

Anesthesia and analgesia, 2017-01, Vol.124 (1), p.44-51

2017

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Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P‐Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What?

Clinical pharmacology and therapeutics, 2018-12, Vol.104 (6), p.1249-1259

2018

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Identification and Functional Assessment of Eight CYP3A4 Allelic Variants 39-46 Detected in the Chinese Han Population

Drug metabolism and disposition, 2024-03, Vol.52 (3), p.218

2024

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Evaluation of Mutual Drug–Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method

Basic & clinical pharmacology & toxicology, 2016-09, Vol.119 (3), p.284-290

2016

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Association of genetic polymorphisms of CYP3A4 and CYP2D6 with gefitinib-induced toxicities

Anti-cancer drugs, 2022-11, Vol.33 (10), p.1139

2022

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Comparative Intra‐Subject Analysis of Gene Expression and Protein Abundance of Major and Minor Drug Metabolizing Enzymes in Healthy Human Jejunum and Liver

Clinical pharmacology and therapeutics, 2024-02, Vol.115 (2), p.221-230

2024

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Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5

Journal of the American Chemical Society, 2021-11, Vol.143 (44), p.18467-18480

2021

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing

Clinical pharmacology and therapeutics, 2015-07, Vol.98 (1), p.19-24

2015

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Heterologous expression of high-activity cytochrome P450 in mammalian cells

Scientific reports, 2020-08, Vol.10 (1), p.14193, Article 14193

2020

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Mechanistic insights on nsSNPs on binding site of renin and cytochrome P450 proteins: A computational perceptual study for pharmacogenomics evaluation

Journal of cellular biochemistry, 2021-10, Vol.122 (10), p.1460-1474

2021

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Leveraging Human Plasma‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil

Clinical pharmacology and therapeutics, 2022-02, Vol.111 (2), p.425-434

2022

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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP3A4 and CYP1A2 and antipsychotics

European journal of human genetics : EJHG, 2024-03, Vol.32 (3), p.278-285

2024

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Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism

Archives of biochemistry and biophysics, 2019-09, Vol.673, p.108078-108078, Article 108078

2019

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Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213

Biochemistry (Easton), 2019-03, Vol.58 (10), p.1411-1422

2019

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Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4

Current drug metabolism, 2008-05, Vol.9 (4), p.310

Zhou, Shu-Feng

2008

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Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104993-104993, Article 104993

2023

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In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.448

2010

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Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

British journal of clinical pharmacology, 2019-01, Vol.85 (1), p.216-226

2019

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Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3383

2023

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MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

Scientific reports, 2017-09, Vol.7 (1), p.12331-11, Article 12331

2017

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CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?

Omics (Larchmont, N.Y.), 2017-09, Vol.21 (9), p.509

2017

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Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes

Drug metabolism and disposition, 2023-02, Vol.51 (2), p.174-182

2023

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