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1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

Bioorganic chemistry, 2018-12, Vol.81, p.1-20

2018

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1,2,3-Triazolyl ester of Ketorolac: A “Click Chemistry”-based highly potent PAK1-blocking cancer-killer

European journal of medicinal chemistry, 2017-01, Vol.126, p.270-276

2017

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1,2-Diaryl-1-ethanone and pyrazolo [4,3- c] quinoline-4-one as novel selective cyclooxygenase-2 inhibitors

Bioorganic & medicinal chemistry letters, 2004-01, Vol.14 (2), p.445-448

2004

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1,2-Diarylimidazoles as Inhibitors of Cyclooxygenase-2: A Quantitative Structure-Activity Relationship Study

Journal of enzyme inhibition, 1999, Vol.14 (4), p.277-288

1999

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1,2-Diarylimidazoles as Potent, Cyclooxygenase-2 Selective, and Orally Active Antiinflammatory Agents

Journal of medicinal chemistry, 1997-05, Vol.40 (11), p.1634-1647

1997

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1,2-Diarylpyrroles as Potent and Selective Inhibitors of Cyclooxygenase-2

Journal of medicinal chemistry, 1997-05, Vol.40 (11), p.1619-1633

1997

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1,25 dihydroxyvitamin D3 and dexamethasone induce the cyclooxygenase 1 gene in osteoclast‐supporting stromal cells

Journal of cellular biochemistry, 1999-09, Vol.74 (4), p.587-595

1999

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1,25-Dihydroxyvitamin D3 induces NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human neonatal monocytes

Blood, 1997-03, Vol.89 (6), p.2105-2112

1997

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1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents

Bioorganic chemistry, 2014-06, Vol.54, p.51-59

2014

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1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

Journal of medicinal chemistry, 2000-11, Vol.43 (24), p.4582-4593

2000

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1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (6), p.601-604

2000

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1,4-Diaryl-substituted triazoles as cyclooxygenase-2 inhibitors: Synthesis, biological evaluation and molecular modeling studies

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4288-4295

2013

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1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study

Bioorganic chemistry, 2019-03, Vol.84, p.76-86

2019

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1-(4-Methane(amino)sulfonylphenyl)-3-(4-substituted-phenyl)-5-(4-trifluoromethylphenyl)-1H-2-pyrazolines/pyrazoles as potential anti-inflammatory agents

Bioorganic chemistry, 2015-12, Vol.63, p.13-23

2015

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1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: Synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity

European journal of medicinal chemistry, 2014-04, Vol.77, p.155-165

2014

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1,5-Diarylpyrrole-3-acetic Acids and Esters as Novel Classes of Potent and Highly Selective Cyclooxygenase-2 Inhibitors

Journal of medicinal chemistry, 2005-05, Vol.48 (9), p.3428-3432

2005

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IL-1 activates two phospholipid signaling pathways in intestinal epithelial cells

Inflammation research, 2001-07, Vol.50 (7), p.375-381

2001

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IL-1β induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1β and IL-6 in human tendon cells

Journal of orthopaedic research, 2003-03, Vol.21 (2), p.256-264

2003

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1-O-Tigloyl-1-O-deacetyl-nimbolinin B Inhibits LPS-Stimulated Inflammatory Responses by Suppressing NF-κB and JNK Activation in Microglia Cells

Journal of Pharmacological Sciences, 2014/08/20, Vol.125(4), pp.364-374

2014

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1-Phenyl-6,7-dihydroxy-isochroman suppresses lipopolysaccharide-induced pro-inflammatory mediator production in human monocytes

British journal of nutrition, 2011-07, Vol.106 (1), p.33-36

2011

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1-Toluene-sulfonyl-3-[(3′-hydroxy-5′-substituted)-γ-butyrolactone]-indoles: Synthesis, COX-2 inhibition and anti-cancer activities

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.85-89

2008

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10E12Z CLA alters adipocyte differentiation and adipocyte cytokine expression and induces macrophage proliferation

The Journal of nutritional biochemistry, 2012-05, Vol.23 (5), p.510-518

2012

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10t,12c-conjugated linoleic acid inhibits lipopolysaccharide-induced cyclooxygenase expression in vitro and in vivo

Journal of lipid research, 2005-10, Vol.46 (10), p.2134-2142

2005

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11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury

Molecular medicine reports, 2016-07, Vol.14 (1), p.874-880

2016

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11-Oxoeicosatetraenoic Acid Is a Cyclooxygenase-2/15-Hydroxyprostaglandin Dehydrogenase-Derived Antiproliferative Eicosanoid

Chemical research in toxicology, 2011-12, Vol.24 (12), p.2227-2236

2011

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1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

1,2,3-Triazolyl ester of Ketorolac: A “Click Chemistry”-based highly potent PAK1-blocking cancer-killer

1,2-Diaryl-1-ethanone and pyrazolo [4,3- c] quinoline-4-one as novel selective cyclooxygenase-2 inhibitors

1,2-Diarylimidazoles as Inhibitors of Cyclooxygenase-2: A Quantitative Structure-Activity Relationship Study

1,2-Diarylimidazoles as Potent, Cyclooxygenase-2 Selective, and Orally Active Antiinflammatory Agents

1,2-Diarylpyrroles as Potent and Selective Inhibitors of Cyclooxygenase-2

1,25 dihydroxyvitamin D3 and dexamethasone induce the cyclooxygenase 1 gene in osteoclast‐supporting stromal cells

1,25-Dihydroxyvitamin D3 induces NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human neonatal monocytes

1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents

1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

1,4-Diaryl-substituted triazoles as cyclooxygenase-2 inhibitors: Synthesis, biological evaluation and molecular modeling studies

1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study

1-(4-Methane(amino)sulfonylphenyl)-3-(4-substituted-phenyl)-5-(4-trifluoromethylphenyl)-1H-2-pyrazolines/pyrazoles as potential anti-inflammatory agents

1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: Synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity

1,5-Diarylpyrrole-3-acetic Acids and Esters as Novel Classes of Potent and Highly Selective Cyclooxygenase-2 Inhibitors

IL-1 activates two phospholipid signaling pathways in intestinal epithelial cells

IL-1β induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1β and IL-6 in human tendon cells

1-O-Tigloyl-1-O-deacetyl-nimbolinin B Inhibits LPS-Stimulated Inflammatory Responses by Suppressing NF-κB and JNK Activation in Microglia Cells

1-Phenyl-6,7-dihydroxy-isochroman suppresses lipopolysaccharide-induced pro-inflammatory mediator production in human monocytes

1-Toluene-sulfonyl-3-[(3′-hydroxy-5′-substituted)-γ-butyrolactone]-indoles: Synthesis, COX-2 inhibition and anti-cancer activities

10E12Z CLA alters adipocyte differentiation and adipocyte cytokine expression and induces macrophage proliferation

10t,12c-conjugated linoleic acid inhibits lipopolysaccharide-induced cyclooxygenase expression in vitro and in vivo

11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury

11-Oxoeicosatetraenoic Acid Is a Cyclooxygenase-2/15-Hydroxyprostaglandin Dehydrogenase-Derived Antiproliferative Eicosanoid

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