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Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication

The Journal of pharmacology and experimental therapeutics, 2011-06, Vol.337 (3), p.655-662

2011

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Structure of the CCR5 Chemokine Receptor—HIV Entry Inhibitor Maraviroc Complex

Science (American Association for the Advancement of Science), 2013-09, Vol.341 (6152), p.1387-1390

2013

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Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival

Drug discovery today, 2012-05, Vol.17 (9-10), p.419-424

2012

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Diverse intracellular pathogens activate type III interferon expression from peroxisomes

Nature immunology, 2014-08, Vol.15 (8), p.717-726

2014

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CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

Cancer research (Chicago, Ill.), 2012-08, Vol.72 (15), p.3839-3850

2012

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Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Immunity (Cambridge, Mass.), 2017-06, Vol.46 (6), p.1005-1017.e5

2017

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Maraviroc reduces neuropathic pain through polarization of microglia and astroglia – Evidence from in vivo and in vitro studies

Neuropharmacology, 2016-09, Vol.108, p.207-219

2016

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Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

Antimicrobial Agents and Chemotherapy, 2005-11, Vol.49 (11), p.4721-4732

2005

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Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

British journal of pharmacology, 2007-03, Vol.150 (5), p.613-623

2007

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Maraviroc versus Efavirenz, Both in Combination with Zidovudine-Lamivudine, for the Treatment of Antiretroviral-Naive Subjects with CCR5-tropic HIV-1 Infection

The Journal of infectious diseases, 2010-03, Vol.201 (6), p.803-813

2010

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Lysine-Specific Demethylase 1 (LSD1) Inhibitors: Peptides as an Emerging Class of Therapeutics

ACS chemical biology, 2023-10, Vol.18 (10), p.2144-2155

2023

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Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

The New England journal of medicine, 2012-07, Vol.367 (2), p.135-145

2012

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Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

AIDS (London), 2022-01, Vol.36 (1), p.11-18

2022

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Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

British journal of pharmacology, 2014-08, Vol.171 (16), p.3908-3917

2014

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Cooperative Dynamics of AR and ER Activity in Breast Cancer

Molecular cancer research, 2016-11, Vol.14 (11), p.1054-1067

2016

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A Novel Synthesized Cyclohexane-Hydroxytyrosol Derivative Suppresses Ovarian Cancer Cell Growth Through Inducing Reactive Oxidative Species and Blocking Autophagic Flux

Antioxidants & redox signaling, 2024-09, Vol.41 (7-9), p.430-461

2024

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How natural infection by Nosema ceranae causes honeybee colony collapse

Environmental microbiology, 2008-10, Vol.10 (10), p.2659-2669

2008

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Nosema ceranae escapes fumagillin control in honey bees

PLoS pathogens, 2013-03, Vol.9 (3), p.e1003185

2013

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mGlu2/3 receptor antagonism: A mechanism to induce rapid antidepressant effects without ketamine-associated side-effects

Pharmacology, biochemistry and behavior, 2020-03, Vol.190, p.172854, Article 172854

Witkin, Jeffrey M.

2020

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Constituents of the Rhizomes of Boesenbergia pandurata and Their Antiausterity Activities against the PANC‑1 Human Pancreatic Cancer Line

Journal of natural products (Washington, D.C.), 2017-01, Vol.80 (1), p.141-148

2017

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Fumagillin: An Overview of Recent Scientific Advances and Their Significance for Apiculture

Journal of agricultural and food chemistry, 2014-04, Vol.62 (13), p.2728-2737

2014

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Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds

PloS one, 2020-01, Vol.15 (1), p.e0227484-e0227484

2020

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Electrospun Solid Dispersions of Maraviroc for Rapid Intravaginal Preexposure Prophylaxis of HIV

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4855-4865

2014

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Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1 R ,2 R and 1 S ,2 S enantiomers of the trans -1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin

Dalton transactions : an international journal of inorganic chemistry, 2021-11, Vol.50 (43), p.15655-15668

2021

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Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication

Structure of the CCR5 Chemokine Receptor—HIV Entry Inhibitor Maraviroc Complex

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Maraviroc reduces neuropathic pain through polarization of microglia and astroglia – Evidence from in vivo and in vitro studies

Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

Maraviroc versus Efavirenz, Both in Combination with Zidovudine-Lamivudine, for the Treatment of Antiretroviral-Naive Subjects with CCR5-tropic HIV-1 Infection

Lysine-Specific Demethylase 1 (LSD1) Inhibitors: Peptides as an Emerging Class of Therapeutics

Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease

Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

Cooperative Dynamics of AR and ER Activity in Breast Cancer

A Novel Synthesized Cyclohexane-Hydroxytyrosol Derivative Suppresses Ovarian Cancer Cell Growth Through Inducing Reactive Oxidative Species and Blocking Autophagic Flux

How natural infection by Nosema ceranae causes honeybee colony collapse

Nosema ceranae escapes fumagillin control in honey bees

mGlu2/3 receptor antagonism: A mechanism to induce rapid antidepressant effects without ketamine-associated side-effects

Constituents of the Rhizomes of Boesenbergia pandurata and Their Antiausterity Activities against the PANC‑1 Human Pancreatic Cancer Line

Fumagillin: An Overview of Recent Scientific Advances and Their Significance for Apiculture

Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds

Electrospun Solid Dispersions of Maraviroc for Rapid Intravaginal Preexposure Prophylaxis of HIV

Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1 R ,2 R and 1 S ,2 S enantiomers of the trans -1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin

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