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Cyclobutanes in Small‐Molecule Drug Candidates

ChemMedChem, 2022-05, Vol.17 (9), p.e202200020-n/a

2022

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Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1130-1152

2018

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Squaraine Dyes: Molecular Design for Different Applications and Remaining Challenges

Bioconjugate chemistry, 2020-02, Vol.31 (2), p.194-213

2020

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Intermolecular Formal Cycloaddition of Indoles with Bicyclo[1.1.0]butanes by Lewis Acid Catalysis

Angewandte Chemie International Edition, 2023-11, Vol.62 (48), p.e202308606-n/a

2023

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J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

Chemical communications (Cambridge, England), 2018-11, Vol.54 (95), p.13395-13398

2018

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Emerging Fusarium and Alternaria Mycotoxins: Occurrence, Toxicity and Toxicokinetics

Toxins, 2017-07, Vol.9 (7), p.228

2017

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Enantioselective Crossed Photocycloadditions of Styrenic Olefins by Lewis Acid Catalyzed Triplet Sensitization

Angewandte Chemie International Edition, 2017-09, Vol.56 (39), p.11891-11895

International ed. in English, 2017

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Asymmetric Catalytic Cascade Reactions for Constructing Diverse Scaffolds and Complex Molecules

Accounts of chemical research, 2015-07, Vol.48 (7), p.1832-1844

2015

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[2+2] Photochemical Cycloaddition in Organic Synthesis

European journal of organic chemistry, 2020-03, Vol.2020 (10), p.1310-1326

2020

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Enantioselective Synthesis of Cyclobutenes by Intermolecular [2+2] Cycloaddition with Non‑C 2 Symmetric Digold Catalysts

Journal of the American Chemical Society, 2017-10, Vol.139 (39), p.13628-13631

2017

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New Catalytic Radical Process Involving 1,4-Hydrogen Atom Abstraction: Asymmetric Construction of Cyclobutanones

Journal of the American Chemical Society, 2021-08, Vol.143 (30), p.11670-11678

2021

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Asymmetric Organocatalytic Formal [2 + 2]-Cycloadditions via Bifunctional H-Bond Directing Dienamine Catalysis

Journal of the American Chemical Society, 2012-02, Vol.134 (5), p.2543-2546

2012

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A Dual-Catalysis Approach to Enantioselective [2 + 2] Photocycloadditions Using Visible Light

Science (American Association for the Advancement of Science), 2014-04, Vol.344 (6182), p.392-396

2014

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Visible Light Photocatalysis of [2+2] Styrene Cycloadditions by Energy Transfer

Angewandte Chemie International Edition, 2012-10, Vol.51 (41), p.10329-10332

International ed. in English, 2012

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Lessons in Strain and Stability: Enantioselective Synthesis of (+)‐[5]‐Ladderanoic Acid

Angewandte Chemie International Edition, 2020-01, Vol.59 (1), p.436-441

International ed. in English, 2020

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Intramolecular Crossed [2+2] Photocycloaddition through Visible Light-Induced Energy Transfer

Journal of the American Chemical Society, 2017-07, Vol.139 (29), p.9807-9810

2017

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Cyclobutenes: At a Crossroad between Diastereoselective Syntheses of Dienes and Unique Palladium-Catalyzed Asymmetric Allylic Substitutions

Accounts of chemical research, 2016-11, Vol.49 (11), p.2444-2458

2016

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Unusually Chemoselective Photocyclization of 2‑(Hydroxyimino)aldehydes to Cyclobutanol Oximes: Synthetic, Stereochemical, and Mechanistic Aspects

Journal of organic chemistry, 2022-11, Vol.87 (21), p.13803-13818

2022

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Naturally occurring bioactive Cyclobutane-containing (CBC) alkaloids in fungi, fungal endophytes, and plants

Phytomedicine (Stuttgart), 2014-10, Vol.21 (12), p.1559-1581

Dembitsky, Valery M.

2014

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Squaraine dyes in PDT: from basic design to in vivo demonstration

Organic & biomolecular chemistry, 2012-02, Vol.1 (5), p.911-92

2012

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Ultrabright and Serum-Stable Squaraine Dyes

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9436-9445

2020

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Stereoselective Solid-State Synthesis of Biologically Active Cyclobutane and Dicyclobutane Isomers via Conformation Blocking and Transference

Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2909

2024

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Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.5051-5062

2016

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Two Hematological Markers Predicting the Efficacy and Prognosis of Neoadjuvant Chemotherapy Using Lobaplatin Against Triple-Negative Breast Cancer

The oncologist (Dayton, Ohio), 2024-05, Vol.29 (5), p.e635-e642

2024

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Applications of C–H Functionalization Logic to Cyclobutane Synthesis

Journal of organic chemistry, 2014-03, Vol.79 (6), p.2430-2452

2014

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Cyclobutanes in Small‐Molecule Drug Candidates

Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Squaraine Dyes: Molecular Design for Different Applications and Remaining Challenges

Intermolecular Formal Cycloaddition of Indoles with Bicyclo[1.1.0]butanes by Lewis Acid Catalysis

J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy

Emerging Fusarium and Alternaria Mycotoxins: Occurrence, Toxicity and Toxicokinetics

Enantioselective Crossed Photocycloadditions of Styrenic Olefins by Lewis Acid Catalyzed Triplet Sensitization

Asymmetric Catalytic Cascade Reactions for Constructing Diverse Scaffolds and Complex Molecules

[2+2] Photochemical Cycloaddition in Organic Synthesis

Enantioselective Synthesis of Cyclobutenes by Intermolecular [2+2] Cycloaddition with Non‑C 2 Symmetric Digold Catalysts

New Catalytic Radical Process Involving 1,4-Hydrogen Atom Abstraction: Asymmetric Construction of Cyclobutanones

Asymmetric Organocatalytic Formal [2 + 2]-Cycloadditions via Bifunctional H-Bond Directing Dienamine Catalysis

A Dual-Catalysis Approach to Enantioselective [2 + 2] Photocycloadditions Using Visible Light

Visible Light Photocatalysis of [2+2] Styrene Cycloadditions by Energy Transfer

Lessons in Strain and Stability: Enantioselective Synthesis of (+)‐[5]‐Ladderanoic Acid

Intramolecular Crossed [2+2] Photocycloaddition through Visible Light-Induced Energy Transfer

Cyclobutenes: At a Crossroad between Diastereoselective Syntheses of Dienes and Unique Palladium-Catalyzed Asymmetric Allylic Substitutions

Unusually Chemoselective Photocyclization of 2‑(Hydroxyimino)aldehydes to Cyclobutanol Oximes: Synthetic, Stereochemical, and Mechanistic Aspects

Naturally occurring bioactive Cyclobutane-containing (CBC) alkaloids in fungi, fungal endophytes, and plants

Squaraine dyes in PDT: from basic design to in vivo demonstration

Ultrabright and Serum-Stable Squaraine Dyes

Stereoselective Solid-State Synthesis of Biologically Active Cyclobutane and Dicyclobutane Isomers via Conformation Blocking and Transference

Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H

Two Hematological Markers Predicting the Efficacy and Prognosis of Neoadjuvant Chemotherapy Using Lobaplatin Against Triple-Negative Breast Cancer

Applications of C–H Functionalization Logic to Cyclobutane Synthesis

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