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Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2

Nature communications, 2021-06, Vol.12 (1), p.3356-3356, Article 3356

2021

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Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

Nucleic acids research, 2016-04, Vol.44 (6), p.2846

2016

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Targeting cell-cycle machinery in cancer

Cancer cell, 2021-06, Vol.39 (6), p.759-778

2021

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Amniotic membrane‐derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest

Journal of cellular and molecular medicine, 2012-09, Vol.16 (9), p.2208-2218

2012

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Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

Scientific reports, 2018-02, Vol.8 (1), p.2709-16, Article 2709

2018

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A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression

Molecular cell, 2013-04, Vol.50 (2), p.250-260

2013

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Targeting CDK4 and CDK6: From Discovery to Therapy

Cancer discovery, 2016-04, Vol.6 (4), p.353-367

2016

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TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase

Biochemical and biophysical research communications, 2017-04, Vol.486 (2), p.385-390

2017

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Mouse Development and Cell Proliferation in the Absence of D-Cyclins

Cell, 2004-08, Vol.118 (4), p.477-491

2004

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Quantitative Proteomics Reveals the Basis for the Biochemical Specificity of the Cell-Cycle Machinery

Molecular cell, 2011-08, Vol.43 (3), p.406-417

2011

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Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation

Cell, 2015-11, Vol.163 (5), p.1225-1236

2015

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Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

Scientific reports, 2019-12, Vol.9 (1), p.18693-17, Article 18693

2019

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Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

Nature communications, 2018-05, Vol.9 (1), p.1876-15, Article 1876

2018

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Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

Cell, 2018-03, Vol.173 (1), p.104-116.e12

2018

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Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

Oncogene, 2009-08, Vol.28 (33), p.2925-2939

2009

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Allostery governs Cdk2 activation and differential recognition of CDK inhibitors

Nature chemical biology, 2021-04, Vol.17 (4), p.456

2021

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Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

Oncogene, 2015-05, Vol.34 (19), p.2538-2545

2015

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Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling

Biochemical and biophysical research communications, 2020-12, Vol.533 (4), p.1162-1169

2020

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A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

Cancer cell, 2011-11, Vol.20 (5), p.620-634

2011

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Mechanistic insights into avian reovirus p17-modulated suppression of cell cycle CDK–cyclin complexes and enhancement of p53 and cyclin H interaction

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12542-12562

2018

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Acute renal failure during sepsis: Potential role of cell cycle regulation

The Journal of infection, 2009-06, Vol.58 (6), p.459-464

2009

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CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition

Scientific reports, 2022-10, Vol.12 (1), p.16810-16810, Article 16810

2022

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regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

The Journal of cell biology, 2008-03, Vol.180 (5), p.915-929

2008

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SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

British journal of cancer, 2017-10, Vol.117 (8), p.1154-1163

2017

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Cyclins and CDKS in development and cancer: lessons from genetically modified mice

Frontiers in bioscience, 2006-01, Vol.11, p.1164

2006

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Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

Targeting cell-cycle machinery in cancer

Amniotic membrane‐derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest

Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression

Targeting CDK4 and CDK6: From Discovery to Therapy

TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase

Mouse Development and Cell Proliferation in the Absence of D-Cyclins

Quantitative Proteomics Reveals the Basis for the Biochemical Specificity of the Cell-Cycle Machinery

Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation

Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

Allostery governs Cdk2 activation and differential recognition of CDK inhibitors

Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling

A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

Mechanistic insights into avian reovirus p17-modulated suppression of cell cycle CDK–cyclin complexes and enhancement of p53 and cyclin H interaction

Acute renal failure during sepsis: Potential role of cell cycle regulation

CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition

regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

Cyclins and CDKS in development and cancer: lessons from genetically modified mice

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