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TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase

Biochemical and biophysical research communications, 2017-04, Vol.486 (2), p.385-390

2017

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Amniotic membrane‐derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest

Journal of cellular and molecular medicine, 2012-09, Vol.16 (9), p.2208-2218

2012

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Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2

Nature communications, 2021-06, Vol.12 (1), p.3356-3356, Article 3356

2021

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Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways

International journal of molecular sciences, 2012-01, Vol.13 (1), p.828-839

2012

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Psoriatic epidermis is associated with upregulation of CDK2 and inhibition of CDK4 activity

British journal of dermatology (1951), 2020-03, Vol.182 (3), p.678-689

2020

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Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (36), p.17990-18000

2019

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Targeting CDK4 and CDK6: From Discovery to Therapy

Cancer discovery, 2016-04, Vol.6 (4), p.353-367

2016

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CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition

Clinical cancer research, 2024-07, Vol.30 (14), p.2996-3005

2024

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PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulation

Molecular cancer research, 2014-03, Vol.12 (3), p.322-334

2014

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MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21

Science translational medicine, 2019-08, Vol.11 (505)

2019

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ClC-3 Chloride Channel Proteins Regulate the Cell Cycle by Up-regulating cyclin D1-CDK4/6 through Suppressing p21/p27 Expression in Nasopharyngeal Carcinoma Cells

Scientific reports, 2016-07, Vol.6 (1), p.30276-30276, Article 30276

2016

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Epigenetic regulation of the INK4b-ARF-INK4a locus: In sickness and in health

Epigenetics, 2010-11, Vol.5 (8), p.685-690

2010

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Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

Molecular biology reports, 2021, Vol.48 (1), p.915-925

2021

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Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients

Breast cancer research and treatment, 2019-11, Vol.178 (1), p.57-62

2019

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Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Cell cycle (Georgetown, Tex.), 2015-04, Vol.14 (8), p.1252-1259

2015

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Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells

Experimental biology and medicine (Maywood, N.J.), 2011-11, Vol.236 (11), p.1351-1359

2011

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The effect of miR‐340 over‐expression on cell‐cycle–related genes in triple‐negative breast cancer cells

European journal of cancer care, 2017-11, Vol.26 (6), p.e12496-n/a

2017

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Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

Cell death & disease, 2018-10, Vol.9 (11), p.1100-12, Article 1100

2018

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PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

PloS one, 2013-10, Vol.8 (10), p.e77639

2013

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Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation

eLife, 2020-04, Vol.9

2020

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Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells

BMC cancer, 2014-01, Vol.14 (1), p.32-32, Article 32

2014

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Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice

The Journal of clinical investigation, 2016-11, Vol.126 (11), p.4076-4087

2016

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CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point

PLoS genetics, 2013-05, Vol.9 (5), p.e1003546-e1003546

2013

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regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

The Journal of cell biology, 2008-03, Vol.180 (5), p.915-929

2008

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Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence

Nature communications, 2024-10, Vol.15 (1), p.9181-16, Article 9181

2024

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TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase

Amniotic membrane‐derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest

Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2

Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways

Psoriatic epidermis is associated with upregulation of CDK2 and inhibition of CDK4 activity

Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

Targeting CDK4 and CDK6: From Discovery to Therapy

CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition

PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulation

MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21

ClC-3 Chloride Channel Proteins Regulate the Cell Cycle by Up-regulating cyclin D1-CDK4/6 through Suppressing p21/p27 Expression in Nasopharyngeal Carcinoma Cells

Epigenetic regulation of the INK4b-ARF-INK4a locus: In sickness and in health

Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors

Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients

Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells

The effect of miR‐340 over‐expression on cell‐cycle–related genes in triple‐negative breast cancer cells

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation

Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice

CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point

regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence

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