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Structure of native lens connexin 46/50 intercellular channels by cryo-EM

Nature (London), 2018-12, Vol.564 (7736), p.372-377

2018

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Hypoxia‑induced internalization of connexin 26 and connexin 43 in pulmonary epithelial cells is involved in the occurrence of non‑small cell lung cancer via the P53/MDM2 signaling pathway

International journal of oncology, 2019-10, Vol.55 (4), p.845-859

2019

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Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

American Journal of Physiology: Cell Physiology, 2007-09, Vol.293 (3), p.C1112-C1119

2007

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Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC

The Journal of cell biology, 2007-12, Vol.179 (6), p.1301-1309

2007

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Very-Low-Density Lipoprotein of Metabolic Syndrome Modulates Gap Junctions and Slows Cardiac Conduction

Scientific reports, 2017-09, Vol.7 (1), p.12050-12, Article 12050

2017

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Engineered Cx26 variants established functional heterotypic Cx26/Cx43 and Cx26/Cx40 gap junction channels

Biochemical journal, 2016-05, Vol.473 (10), p.1391-1403

2016

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Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels

Journal of molecular and cellular cardiology, 2017-10, Vol.111, p.17-26

2017

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Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging

The Journal of biological chemistry, 2020-12, Vol.295 (49), p.16499-16509

2020

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Connexin Family Members Target to Lipid Raft Domains and Interact with Caveolin-1

Biochemistry (Easton), 2002-05, Vol.41 (18), p.5754-5764

2002

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Computational simulations of asymmetric fluxes of large molecules through gap junction channel pores

Journal of theoretical biology, 2017-01, Vol.412, p.61-73

2017

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The distribution and functional properties of Pelizaeus-Merzbacher-like disease-linked Cx47 mutations on Cx47/Cx47 homotypic and Cx47/Cx43 heterotypic gap junctions

Biochemical journal, 2013-06, Vol.452 (2), p.249-258

2013

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Direct integration of cell-free-synthesized connexin-43 into liposomes and hemichannel formation

The FEBS journal, 2010-08, Vol.277 (16), p.3343-3352

2010

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Structures of human pannexin 1 reveal ion pathways and mechanism of gating

Nature (London), 2020-08, Vol.584 (7822), p.646-651

2020

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Life cycle of connexins in health and disease

Biochemical journal, 2006-03, Vol.394 (Pt 3), p.527-543

Laird, Dale W

2006

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The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition

eLife, 2020-02, Vol.9

2020

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Engineered Cx40 variants increased docking and function of heterotypic Cx40/Cx43 gap junction channels

Journal of molecular and cellular cardiology, 2016-01, Vol.90, p.11-20

2016

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Cryo-EM structures of the ATP release channel pannexin 1

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.373-381

2020

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Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17074-17084

2015

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Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability

Scientific reports, 2021-12, Vol.11 (1), p.24334-24334, Article 24334

2021

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SnapShot: Connexins and Disease

Cell, 2017-09, Vol.170 (6), p.1260-1260.e1

2017

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Gating Properties of Heterotypic Gap Junction Channels Formed of Connexins 40, 43, and 45

Biophysical journal, 2007-03, Vol.92 (6), p.1952-1965

2007

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Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides

The Journal of general physiology, 2008-04, Vol.131 (4), p.293-305

2008

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Voltage-dependent conformational changes in connexin channels

Biochimica et biophysica acta, 2012-08, Vol.1818 (8), p.1807-1822

2012

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Conformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel

The Journal of general physiology, 2009-06, Vol.133 (6), p.555-570

2009

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Some Oculodentodigital Dysplasia-Associated Cx43 Mutations Cause Increased Hemichannel Activity in Addition to Deficient Gap Junction Channels

The Journal of membrane biology, 2007-10, Vol.219 (1-3), p.9-17

2007

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Structure of native lens connexin 46/50 intercellular channels by cryo-EM

Hypoxia‑induced internalization of connexin 26 and connexin 43 in pulmonary epithelial cells is involved in the occurrence of non‑small cell lung cancer via the P53/MDM2 signaling pathway

Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC

Very-Low-Density Lipoprotein of Metabolic Syndrome Modulates Gap Junctions and Slows Cardiac Conduction

Engineered Cx26 variants established functional heterotypic Cx26/Cx43 and Cx26/Cx40 gap junction channels

Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels

Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by atomic force microscopy imaging

Connexin Family Members Target to Lipid Raft Domains and Interact with Caveolin-1

Computational simulations of asymmetric fluxes of large molecules through gap junction channel pores

The distribution and functional properties of Pelizaeus-Merzbacher-like disease-linked Cx47 mutations on Cx47/Cx47 homotypic and Cx47/Cx43 heterotypic gap junctions

Direct integration of cell-free-synthesized connexin-43 into liposomes and hemichannel formation

Structures of human pannexin 1 reveal ion pathways and mechanism of gating

Life cycle of connexins in health and disease

The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition

Engineered Cx40 variants increased docking and function of heterotypic Cx40/Cx43 gap junction channels

Cryo-EM structures of the ATP release channel pannexin 1

Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32

Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability

SnapShot: Connexins and Disease

Gating Properties of Heterotypic Gap Junction Channels Formed of Connexins 40, 43, and 45

Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides

Voltage-dependent conformational changes in connexin channels

Conformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel

Some Oculodentodigital Dysplasia-Associated Cx43 Mutations Cause Increased Hemichannel Activity in Addition to Deficient Gap Junction Channels

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