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Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

Nature (London), 2014-11, Vol.515 (7525), p.130-133

2014

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The regulation and importance of monocyte chemoattractant protein-1

Current opinion in hematology, 2018-01, Vol.25 (1), p.44-51

2018

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ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation

Cellular and molecular life sciences : CMLS, 2022-03, Vol.79 (3), p.155-155, Article 155

2022

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CCL2 recruits inflammatory monocytes to facilitate breast―tumour metastasis

Nature (London), 2011-07, Vol.475 (7355), p.222-225

2011

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p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

The Journal of experimental medicine, 2013-09, Vol.210 (10), p.2057-2069

2013

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TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

Brain (London, England : 1878), 2016-05, Vol.139 (Pt 5), p.1361-1377

2016

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MCP-1: Chemoattractant with a role beyond immunity: A review

Clinica chimica acta, 2010-11, Vol.411 (21), p.1570-1579

2010

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CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

Cell reports (Cambridge), 2015-07, Vol.12 (2), p.244-257

2015

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Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice

Circulation (New York, N.Y.), 2008-04, Vol.117 (13), p.1649-1657

2008

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Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease

Clinical science (1979), 2017-06, Vol.131 (12), p.1215

2017

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Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

Cytokine (Philadelphia, Pa.), 2012-10, Vol.60 (1), p.1-12

Panee, Jun

2012

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CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

Gut, 2014-12, Vol.63 (12), p.1960-1971

2014

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Evidence for chemokine synergy during neutrophil migration in ARDS

Thorax, 2017-01, Vol.72 (1), p.66

2017

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Pharmacological inhibition of the chemokine C‐C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly‐6C+ macrophage infiltration in mice

Hepatology (Baltimore, Md.), 2014-03, Vol.59 (3), p.1060-1072

2014

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C-C motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria

Nephrology, dialysis, transplantation, 2017-02, Vol.32 (2), p.307-315

2017

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Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

Gut, 2012-03, Vol.61 (3), p.416-426

2012

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Monocyte chemoattractant protein-1 and the kidney

Current opinion in nephrology and hypertension, 2016-01, Vol.25 (1), p.42-49

2016

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Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma

Investigational new drugs, 2020-06, Vol.38 (3), p.800-811

2020

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MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy

American journal of physiology. Renal physiology, 2008-04, Vol.294 (4), p.F697-F701

Tesch, G H

2008

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The role of CCL2/CCR2 axis in cancer and inflammation: The next frontier in nanomedicine

Advanced drug delivery reviews, 2024-06, Vol.209, p.115318, Article 115318

2024

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CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury

The Journal of neuroscience, 2011-04, Vol.31 (15), p.5865-5875

2011

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The STAT3 inhibitor Stattic acts independently of STAT3 to decrease histone acetylation and modulate gene expression

The Journal of biological chemistry, 2021-01, Vol.296, p.100220, Article 100220

2021

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CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers

Cancer letters, 2007-07, Vol.252 (1), p.86-92

2007

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Frontline Science: Aspirin‐triggered resolvin D1 controls herpes simplex virus‐induced corneal immunopathology

Journal of leukocyte biology, 2017-11, Vol.102 (5), p.1159-1171

2017

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Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model

Molecular cancer therapeutics, 2017-02, Vol.16 (2), p.312-322

2017

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Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

The regulation and importance of monocyte chemoattractant protein-1

ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation

CCL2 recruits inflammatory monocytes to facilitate breast―tumour metastasis

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress

MCP-1: Chemoattractant with a role beyond immunity: A review

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice

Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

Evidence for chemokine synergy during neutrophil migration in ARDS

Pharmacological inhibition of the chemokine C‐C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly‐6C+ macrophage infiltration in mice

C-C motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

Monocyte chemoattractant protein-1 and the kidney

Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma

MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy

The role of CCL2/CCR2 axis in cancer and inflammation: The next frontier in nanomedicine

CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury

The STAT3 inhibitor Stattic acts independently of STAT3 to decrease histone acetylation and modulate gene expression

CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers

Frontline Science: Aspirin‐triggered resolvin D1 controls herpes simplex virus‐induced corneal immunopathology

Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model

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