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Principles of CNS drug development: from test tube to patient

Kelly, John

2009

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Neurosarcoidosis: Clinical, biological, and MRI presentation of central nervous system disease in a national multicenter cohort

Brain and behavior, 2024-09, Vol.14 (9), p.e3443-n/a

2024

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B cells in autoimmune and neurodegenerative central nervous system diseases

Nature reviews. Neuroscience, 2019-12, Vol.20 (12), p.728-745

2019

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From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

Nature reviews. Drug discovery, 2016-04, Vol.15 (4), p.275-292

Banks, William A.

2016

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Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review

European journal of pharmacology, 2019-09, Vol.858, p.172500, Article 172500

2019

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Polyphenols and their applications: An approach in food chemistry and innovation potential

Food chemistry, 2021-02, Vol.338, p.127535-127535, Article 127535

2021

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Kynurenines in the CNS: recent advances and new questions

Nature reviews. Drug discovery, 2013-01, Vol.12 (1), p.64-82

2013

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Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

Progress in neurobiology, 2019-12, Vol.183, p.101694-101694, Article 101694

2019

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Intranasal delivery of biologics to the central nervous system

Advanced drug delivery reviews, 2012-05, Vol.64 (7), p.614-628

2012

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The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

Chemical reviews, 2013-05, Vol.113 (5), p.3516-3604

2013

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Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests

Molecules (Basel, Switzerland), 2019-08, Vol.24 (16), p.2997

2019

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The Role of Magnesium in Neurological Disorders

Nutrients, 2018-06, Vol.10 (6), p.730

2018

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Nanoparticle crossing of blood-brain barrier: a road to new therapeutic approaches to central nervous system diseases

Nanomedicine (London, England), 2018-07, Vol.13 (13), p.1513-1516

2018

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Nicotinic ACh receptors as therapeutic targets in CNS disorders

Trends in pharmacological sciences (Regular ed.), 2015-02, Vol.36 (2), p.96-108

2015

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Mammalian lipoxygenases and their biological relevance

Biochimica et biophysica acta, 2015-04, Vol.1851 (4), p.308-330

2015

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Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders

Expert opinion on therapeutic targets, 2019-10, Vol.23 (10), p.865-882

2019

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The aquaporin-4 water channel as a potential drug target in neurological disorders

Expert opinion on therapeutic targets, 2017-12, Vol.21 (12), p.1161-1170

2017

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Human pluripotent stem cell–derived models and drug screening in CNS precision medicine

Annals of the New York Academy of Sciences, 2020-07, Vol.1471 (1), p.18-56

2020

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Implications of sex-related differences in central nervous system disorders for drug research and development

Nature reviews. Drug discovery, 2021-12, Vol.20 (12), p.881-882

2021

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Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders

Nature reviews. Drug discovery, 2014-09, Vol.13 (9), p.692-708

2014

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Neuropharmacological potentials of β-carboline alkaloids for neuropsychiatric disorders

European journal of pharmacology, 2021-02, Vol.893, p.173837, Article 173837

2021

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Zebrafish models in neuropsychopharmacology and CNS drug discovery

British journal of pharmacology, 2017-07, Vol.174 (13), p.1925-1944

2017

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Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

Pharmacological research, 2016-10, Vol.112, p.4-29

2016

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Neuroimmune Axes of the Blood-Brain Barriers and Blood-Brain Interfaces: Bases for Physiological Regulation, Disease States, and Pharmacological Interventions

Pharmacological reviews, 2018-04, Vol.70 (2), p.278-314

2018

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Extrasynaptic GABA A Receptors: Their Function in the CNS and Implications for Disease

Neuron (Cambridge, Mass.), 2012-01, Vol.73 (1), p.23-34

2012

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Principles of CNS drug development: from test tube to patient

Neurosarcoidosis: Clinical, biological, and MRI presentation of central nervous system disease in a national multicenter cohort

B cells in autoimmune and neurodegenerative central nervous system diseases

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review

Polyphenols and their applications: An approach in food chemistry and innovation potential

Kynurenines in the CNS: recent advances and new questions

Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

Intranasal delivery of biologics to the central nervous system

The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests

The Role of Magnesium in Neurological Disorders

Nanoparticle crossing of blood-brain barrier: a road to new therapeutic approaches to central nervous system diseases

Nicotinic ACh receptors as therapeutic targets in CNS disorders

Mammalian lipoxygenases and their biological relevance

Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders

The aquaporin-4 water channel as a potential drug target in neurological disorders

Human pluripotent stem cell–derived models and drug screening in CNS precision medicine

Implications of sex-related differences in central nervous system disorders for drug research and development

Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders

Neuropharmacological potentials of β-carboline alkaloids for neuropsychiatric disorders

Zebrafish models in neuropsychopharmacology and CNS drug discovery

Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

Neuroimmune Axes of the Blood-Brain Barriers and Blood-Brain Interfaces: Bases for Physiological Regulation, Disease States, and Pharmacological Interventions

Extrasynaptic GABA A Receptors: Their Function in the CNS and Implications for Disease

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