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SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy

Circulation (New York, N.Y.), 2017-11, Vol.136 (21), p.2051-2067

2017

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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

Nature (London), 2015-03, Vol.519 (7544), p.472-476

2015

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Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development-Review

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2935

2021

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ADAMTS16 activates latent TGF-β, accentuating fibrosis and dysfunction of the pressure-overloaded heart

Cardiovascular research, 2020-04, Vol.116 (5), p.956-969

2020

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Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (35), p.E8143-E8152

2018

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Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α

Circulation (New York, N.Y.), 2016-06, Vol.133 (24), p.2447-2458

2016

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Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

Cell death & disease, 2020-07, Vol.11 (7), p.574, Article 574

2020

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A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

Circulation (New York, N.Y.), 2020-01, Vol.141 (3), p.217-233

2020

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Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging

Circulation research, 2014-01, Vol.114 (2), p.368-378

2014

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PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9572-9577

2011

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Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice

American journal of physiology. Heart and circulatory physiology, 2016-04, Vol.310 (8), p.H962-H972

2016

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mTOR, cardiomyocytes and inflammation in cardiac hypertrophy

Biochimica et biophysica acta, 2016-07, Vol.1863 (7), p.1894-1903

2016

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Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

Circulation research, 2010-04, Vol.106 (7), p.1253-1264

2010

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Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition

Journal of the American College of Cardiology, 2014-06, Vol.63 (24), p.2734-2741

2014

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miR-21-3p regulates cardiac hypertrophic response by targeting histone deacetylase-8

Cardiovascular research, 2015-03, Vol.105 (3), p.340-352

2015

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HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling

American journal of physiology. Heart and circulatory physiology, 2014-07, Vol.307 (2), p.H252-H258

2014

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Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

Circulation (New York, N.Y.), 2010-08, Vol.122 (7), p.717-728

2010

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SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

European heart journal, 2017-05, Vol.38 (18), p.1389-1398

2017

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The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy

The Journal of clinical investigation, 2017, Vol.127 (1), p.335-348

2017

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CaMKII in myocardial hypertrophy and heart failure

Journal of molecular and cellular cardiology, 2011-10, Vol.51 (4), p.468-473

2011

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Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2

Circulation research, 2015-09, Vol.117 (8), p.707-719

2015

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Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

Circulation research, 2008-03, Vol.102 (6), p.703-710

2008

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Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

Journal of the American Heart Association, 2017-08, Vol.6 (8), p.n/a

2017

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Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway

Journal of molecular and cellular cardiology, 2019-02, Vol.127, p.134-142

2019

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A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes

Journal of molecular and cellular cardiology, 2015-12, Vol.89 (Pt B), p.268-279

2015

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SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development-Review

ADAMTS16 activates latent TGF-β, accentuating fibrosis and dysfunction of the pressure-overloaded heart

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2α

Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction

Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice

mTOR, cardiomyocytes and inflammation in cardiac hypertrophy

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition

miR-21-3p regulates cardiac hypertrophic response by targeting histone deacetylase-8

HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy

CaMKII in myocardial hypertrophy and heart failure

Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway

A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes

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