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Novel 1,2,3-triazole compounds: Synthesis, In vitro xanthine oxidase inhibitory activity, and molecular docking studies

Journal of molecular structure, 2020-07, Vol.1211, p.128060, Article 128060

Tan, Ayse

2020

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Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature communications, 2018-08, Vol.9 (1), p.3243-12, Article 3243

2018

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Biocatalytic synthesis of chiral five-membered carbasugars intermediates utilizing CV2025 ω-transaminase from Chromobacterium violaceum

Journal of bioscience and bioengineering, 2023-05, Vol.135 (5), p.369-374

2023

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Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics

Chemical Society reviews, 2013-05, Vol.42 (10), p.4270-4283

2013

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Design and synthesis of N–acetylglucosamine derived 5a-carbasugar analogues as glycosidase inhibitors

Tetrahedron, 2018-04, Vol.74 (15), p.1957-1964

2018

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Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases

Chemistry : a European journal, 2021-07, Vol.27 (37), p.9519-9523

2021

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Selective synthesis of 3-deoxy-5-hydroxy-1-amino-carbasugars as potential α-glucosidase inhibitors

Organic & biomolecular chemistry, 2019-05, Vol.17 (21), p.5381-5391

2019

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A concise synthesis of carbasugars isolated from Streptomyces lincolnensis

Tetrahedron, 2020-12, Vol.76 (51), p.131346, Article 131346

2020

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Recent developments in design and synthesis of bicyclic azasugars, carbasugars and related molecules as glycosidase inhibitors

Chemical Society reviews, 2013-01, Vol.42 (12), p.512-5118

2013

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α- and β-Glucosidase inhibitors: chemical structure and biological activity

Tetrahedron, 2006-10, Vol.62 (44), p.10277-10302

2006

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Regio- and stereospecific synthesis of rac-carbasugar-based cyclohexane pentols; Investigations of their α- and β-glucosidase inhibitions

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.4276-4287

2018

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Synthesis of a Novel UDP-carbasugar as UDP-galactopyranose Mutase Inhibitor

Organic letters, 2014-05, Vol.16 (9), p.2462-2465

2014

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Efficient stereoselective synthesis of 5a-carba-α-L-mannopyranose starting from naturally abundant (−)-shikimic acid

Synthetic communications, 2021-11, Vol.51 (22), p.3427-3434

2021

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Application of a tandem seleno-michael/aldol reaction in the total syntheses of (+)-Pericosine B, (+)-Pericosine C, (+)-COTC and 7-chloro-analogue of (+)-Gabosine C

Tetrahedron, 2020-08, Vol.76 (34), p.131397, Article 131397

2020

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A Synthetic Approach to Several C7-Carbasugars via a Key Intramolecular Morita–Baylis–Hillman Reaction

Journal of organic chemistry, 2022-11, Vol.87 (21), p.14636-14645

2022

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Glycoside Hydrolase Catalysis: Do Substrates and Mechanism-Based Covalent Inhibitors React via Matching Transition States?

ACS catalysis, 2022-12, Vol.12 (23), p.14667-14678

2022

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Synthesis of Carba-NAD and the Structures of Its Ternary Complexes with SIRT3 and SIRT5

Journal of organic chemistry, 2012-09, Vol.77 (17), p.7319-7329

2012

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Synthesis and biological evaluation of phosphoramidate prodrugs of two analogues of 2-deoxy-d-ribose-1-phosphate directed to the discovery of two carbasugars as new potential anti-HIV leads

Bioorganic & medicinal chemistry, 2015-02, Vol.23 (4), p.829-838

2015

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Fluoro‐Carba‐Sugars are Glycomimetic Activators of the glmS Ribozyme

Chemistry : a European journal, 2017-09, Vol.23 (51), p.12604-12612

2017

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Synthesis of 5a,5a′-dicarba-d-glucobioses from conformationally restricted carbaglucosyl triflates using SN2-type inversion with carbaglucosyl nucleophiles

Bioorganic & medicinal chemistry, 2019-06, Vol.27 (12), p.2345-2367

2019

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Allylic strain as a stereocontrol element in the hydrogenation of 3-hydroxymethyl-cyclohex-3-en-1,2,5-triol derivatives. Synthesis of the carbasugar pseudo-2-deoxy-α-d-glucopyranose

Tetrahedron, 2018-09, Vol.74 (38), p.5183-5191

2018

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Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters

Tetrahedron, 2020-01, Vol.76 (3), p.130837, Article 130837

2020

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Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition

Chemistry : a European journal, 2024-06, Vol.30 (31), p.e202400723-n/a

2024

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Carbasugar probes to explore the enzyme binding pocket at the anomeric position: application to the design of Golgi mannosidase II inhibitors

Current medicinal chemistry, 2013-10, Vol.20 (30), p.3797-3801

2013

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Versatile synthetic route to carbocyclic N-Acetylneuraminic acid and its derivatives

Tetrahedron, 2018-09, Vol.74 (38), p.5213-5221

2018

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Novel 1,2,3-triazole compounds: Synthesis, In vitro xanthine oxidase inhibitory activity, and molecular docking studies

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Biocatalytic synthesis of chiral five-membered carbasugars intermediates utilizing CV2025 ω-transaminase from Chromobacterium violaceum

Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics

Design and synthesis of N–acetylglucosamine derived 5a-carbasugar analogues as glycosidase inhibitors

Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases

Selective synthesis of 3-deoxy-5-hydroxy-1-amino-carbasugars as potential α-glucosidase inhibitors

A concise synthesis of carbasugars isolated from Streptomyces lincolnensis

Recent developments in design and synthesis of bicyclic azasugars, carbasugars and related molecules as glycosidase inhibitors

α- and β-Glucosidase inhibitors: chemical structure and biological activity

Regio- and stereospecific synthesis of rac-carbasugar-based cyclohexane pentols; Investigations of their α- and β-glucosidase inhibitions

Synthesis of a Novel UDP-carbasugar as UDP-galactopyranose Mutase Inhibitor

Efficient stereoselective synthesis of 5a-carba-α-L-mannopyranose starting from naturally abundant (−)-shikimic acid

Application of a tandem seleno-michael/aldol reaction in the total syntheses of (+)-Pericosine B, (+)-Pericosine C, (+)-COTC and 7-chloro-analogue of (+)-Gabosine C

A Synthetic Approach to Several C7-Carbasugars via a Key Intramolecular Morita–Baylis–Hillman Reaction

Glycoside Hydrolase Catalysis: Do Substrates and Mechanism-Based Covalent Inhibitors React via Matching Transition States?

Synthesis of Carba-NAD and the Structures of Its Ternary Complexes with SIRT3 and SIRT5

Synthesis and biological evaluation of phosphoramidate prodrugs of two analogues of 2-deoxy-d-ribose-1-phosphate directed to the discovery of two carbasugars as new potential anti-HIV leads

Fluoro‐Carba‐Sugars are Glycomimetic Activators of the glmS Ribozyme

Synthesis of 5a,5a′-dicarba-d-glucobioses from conformationally restricted carbaglucosyl triflates using SN2-type inversion with carbaglucosyl nucleophiles

Allylic strain as a stereocontrol element in the hydrogenation of 3-hydroxymethyl-cyclohex-3-en-1,2,5-triol derivatives. Synthesis of the carbasugar pseudo-2-deoxy-α-d-glucopyranose

Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters

Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition

Carbasugar probes to explore the enzyme binding pocket at the anomeric position: application to the design of Golgi mannosidase II inhibitors

Versatile synthetic route to carbocyclic N-Acetylneuraminic acid and its derivatives

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