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β-Lactamases and β-Lactamase Inhibitors in the 21st Century

Journal of molecular biology, 2019-08, Vol.431 (18), p.3472-3500

2019

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New Carbapenemase Inhibitors: Clearing the Way for the β-Lactams

International journal of molecular sciences, 2020-12, Vol.21 (23), p.9308

2020

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Recent updates of carbapenem antibiotics

European journal of medicinal chemistry, 2017-05, Vol.131, p.185-195

2017

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Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours

Journal of Clinical Microbiology, 2011-09, Vol.49 (9), p.3321-3324

2011

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ThnL, a B12-dependent radical S -adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (34), p.e2206494119-e2206494119

2022

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Mechanism of the C5 Stereoinversion Reaction in the Biosynthesis of Carbapenem Antibiotics

Science (American Association for the Advancement of Science), 2014-03, Vol.343 (6175), p.1140-1144

2014

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Tautomer-Specific Deacylation and Ω‑Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC‑2 β‑Lactamase

Journal of the American Chemical Society, 2023-04, Vol.145 (13), p.7166-7180

2023

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Novel metallo-β-lactamases inhibitors restore the susceptibility of carbapenems to New Delhi metallo-lactamase-1 (NDM-1)-harbouring bacteria

British journal of pharmacology, 2024-01, Vol.181 (1), p.54-69

2024

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Comparative review of the carbapenems

Drugs (New York, N.Y.), 2007-01, Vol.67 (7), p.1027-1052

2007

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Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (48), p.30699-30709

2020

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Amplification Curve Analysis: Data-Driven Multiplexing Using Real-Time Digital PCR

Analytical chemistry (Washington), 2020-10, Vol.92 (19), p.13134-13143

2020

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Rapid detection of carbapenemase-producing Enterobacteriaceae

Emerging infectious diseases, 2012-09, Vol.18 (9), p.1503-1507

2012

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A novel tricyclic β-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships

Bioorganic & medicinal chemistry, 2021-09, Vol.46, p.116343-116343, Article 116343

2021

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Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (33), p.10354-10358

2015

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Metabolic engineering of a carbapenem antibiotic synthesis pathway in Escherichia coli

Nature chemical biology, 2018-08, Vol.14 (8), p.794

2018

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Ten Years with New Delhi Metallo-β-lactamase‑1 (NDM-1): From Structural Insights to Inhibitor Design

ACS infectious diseases, 2019-01, Vol.5 (1), p.9-34

2019

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Formulation of carbapenems loaded gold nanoparticles to combat multi-antibiotic bacterial resistance: In vitro antibacterial study

International journal of pharmaceutics, 2017-06, Vol.525 (1), p.71-84

2017

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In-silico screening and experimental validation reveal L-Adrenaline as anti-biofilm molecule against biofilm-associated protein (Bap) producing Acinetobacter baumannii

International journal of biological macromolecules, 2018-02, Vol.107 (Pt A), p.1242-1252

2018

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Synthesis of Carbapenems Containing Peptidoglycan Mimetics and Inhibition of the Cross‐Linking Activity of a Transpeptidase of l,d Specificity

Chemistry : a European journal, 2021-02, Vol.27 (10), p.3542-3551

2021

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Detection of Carbapenemase‐Producing Organisms with a Carbapenem‐Based Fluorogenic Probe

Angewandte Chemie (International ed.), 2017-04, Vol.56 (16), p.4468-4472

International ed. in English, 2017

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A hexasaccharide from capsular polysaccharide of carbapenem-resistant Klebsiella pneumoniae KN2 is a ligand of Toll-like receptor 4

Carbohydrate polymers, 2022-02, Vol.278, p.118944-118944, Article 118944

2022

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Chemiluminescent Carbapenem‐Based Molecular Probe for Detection of Carbapenemase Activity in Live Bacteria

Chemistry : a European journal, 2020-03, Vol.26 (16), p.3647-3652

2020

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Pterostilbene restores carbapenem susceptibility in New Delhi metallo‐β‐lactamase‐producing isolates by inhibiting the activity of New Delhi metallo‐β‐lactamases

British journal of pharmacology, 2019-12, Vol.176 (23), p.4548-4557

2019

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Evaluation of the automated BD Phoenix CPO Detect panel in combination with the β-CARBA assay for detection and classification of carbapenemase-producing Enterobacterales

Journal of microbiological methods, 2019-01, Vol.156, p.29-33

2019

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Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

Critical care (London, England), 2015-12, Vol.19 (1), p.437-437, Article 437

2015

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β-Lactamases and β-Lactamase Inhibitors in the 21st Century

New Carbapenemase Inhibitors: Clearing the Way for the β-Lactams

Recent updates of carbapenem antibiotics

Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours

ThnL, a B12-dependent radical S -adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis

Mechanism of the C5 Stereoinversion Reaction in the Biosynthesis of Carbapenem Antibiotics

Tautomer-Specific Deacylation and Ω‑Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC‑2 β‑Lactamase

Novel metallo-β-lactamases inhibitors restore the susceptibility of carbapenems to New Delhi metallo-lactamase-1 (NDM-1)-harbouring bacteria

Comparative review of the carbapenems

Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli

Amplification Curve Analysis: Data-Driven Multiplexing Using Real-Time Digital PCR

Rapid detection of carbapenemase-producing Enterobacteriaceae

A novel tricyclic β-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships

Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis

Metabolic engineering of a carbapenem antibiotic synthesis pathway in Escherichia coli

Ten Years with New Delhi Metallo-β-lactamase‑1 (NDM-1): From Structural Insights to Inhibitor Design

Formulation of carbapenems loaded gold nanoparticles to combat multi-antibiotic bacterial resistance: In vitro antibacterial study

In-silico screening and experimental validation reveal L-Adrenaline as anti-biofilm molecule against biofilm-associated protein (Bap) producing Acinetobacter baumannii

Synthesis of Carbapenems Containing Peptidoglycan Mimetics and Inhibition of the Cross‐Linking Activity of a Transpeptidase of l,d Specificity

Detection of Carbapenemase‐Producing Organisms with a Carbapenem‐Based Fluorogenic Probe

A hexasaccharide from capsular polysaccharide of carbapenem-resistant Klebsiella pneumoniae KN2 is a ligand of Toll-like receptor 4

Chemiluminescent Carbapenem‐Based Molecular Probe for Detection of Carbapenemase Activity in Live Bacteria

Pterostilbene restores carbapenem susceptibility in New Delhi metallo‐β‐lactamase‐producing isolates by inhibiting the activity of New Delhi metallo‐β‐lactamases

Evaluation of the automated BD Phoenix CPO Detect panel in combination with the β-CARBA assay for detection and classification of carbapenemase-producing Enterobacterales

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

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