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CRY1/2 regulate rhythmic CYP2A5 in mouse liver through repression of E4BP4

Biochemical pharmacology, 2023-11, Vol.217, p.115843-115843, Article 115843

2023

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Cytochrome P450S and Alcoholic Liver Disease

Current pharmaceutical design, 2018-01, Vol.24 (14), p.1502-1517

2018

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Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring

Epigenetics, 2020-12, Vol.15 (12), p.1370-1385

2020

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Circadian rhythms in CYP2A5 expression underlie the time-dependent effect of tegafur on breast cancer

Biochemical and biophysical research communications, 2024-05, Vol.708, p.149813, Article 149813

2024

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Gut Commensal Fungi Protect Against Acetaminophen-Induced Hepatotoxicity by Reducing Cyp2a5 Expression in Mice

Frontiers in microbiology, 2022-07, Vol.13, p.944416-944416

2022

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Activated Hepatic Nuclear Factor-κB in Experimental Colitis Regulates CYP2A5 and Metronidazole Disposition

Molecular pharmaceutics, 2023-02, Vol.20 (2), p.1222-1229

2023

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Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis

Toxicology (Amsterdam), 2017-03, Vol.379, p.12-21

2017

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Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation

International journal of molecular sciences, 2020-12, Vol.22 (1), p.164

2020

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Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: Biochemical, pharmacological and toxicological implications

Journal of proteomics, 2014-08, Vol.108 (100), p.171-187

2014

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Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway

Toxicological sciences, 2012-08, Vol.128 (2), p.427-438

2012

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Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice

Biochemical and biophysical research communications, 2019-04, Vol.512 (1), p.119-124

2019

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High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

Frontiers in pharmacology, 2017-05, Vol.8, p.233-233

2017

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The Impact of Sex on Changes in Plasma Corticosterone and Cotinine Levels Induced by Nicotine in C57BL/6J Mice

Brain sciences, 2020-10, Vol.10 (10), p.1

2020

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Alcoholic Liver Disease: from CYP2E1 to CYP2A5

Current molecular pharmacology, 2017-01, Vol.10 (3), p.172-178

2017

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Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver

Current drug metabolism, 2013-01, Vol.14 (1), p.137-150

2013

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Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

BMC research notes, 2017-03, Vol.10 (1), p.125-125, Article 125

2017

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Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype

PloS one, 2016-11, Vol.11 (11), p.e0167374

2016

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In vivo and in vitro effects of pentavalent antimony on mouse liver cytochrome P450s

Human & experimental toxicology, 2017-01, Vol.36 (1), p.33-41

2017

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Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress

Toxicology and applied pharmacology, 2015-01, Vol.282 (1), p.77-89

2015

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Inducible bilirubin oxidase: A novel function for the mouse cytochrome P450 2A5

Toxicology and applied pharmacology, 2011-11, Vol.257 (1), p.14-22

2011

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Regulation of the cytochrome P450 2A genes

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.285-294

2004

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Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2

Toxicological sciences, 2012-11, Vol.130 (1), p.132-144

2012

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Effects of Fatty Acids on CYP2A5 and Nrf2 Expression in Mouse Primary Hepatocytes

Biochemical genetics, 2016-02, Vol.54 (1), p.29-40

2016

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Effects of 8-methoxypsoralen on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice

Drug metabolism and pharmacokinetics, 2015-08, Vol.30 (4), p.314-320

2015

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Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver

Alcohol (Fayetteville, N.Y.), 2013-08, Vol.47 (5), p.353-357

2013

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CRY1/2 regulate rhythmic CYP2A5 in mouse liver through repression of E4BP4

Cytochrome P450S and Alcoholic Liver Disease

Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring

Circadian rhythms in CYP2A5 expression underlie the time-dependent effect of tegafur on breast cancer

Gut Commensal Fungi Protect Against Acetaminophen-Induced Hepatotoxicity by Reducing Cyp2a5 Expression in Mice

Activated Hepatic Nuclear Factor-κB in Experimental Colitis Regulates CYP2A5 and Metronidazole Disposition

Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis

Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation

Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: Biochemical, pharmacological and toxicological implications

Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway

Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

The Impact of Sex on Changes in Plasma Corticosterone and Cotinine Levels Induced by Nicotine in C57BL/6J Mice

Alcoholic Liver Disease: from CYP2E1 to CYP2A5

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver

Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype

In vivo and in vitro effects of pentavalent antimony on mouse liver cytochrome P450s

Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress

Inducible bilirubin oxidase: A novel function for the mouse cytochrome P450 2A5

Regulation of the cytochrome P450 2A genes

Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2

Effects of Fatty Acids on CYP2A5 and Nrf2 Expression in Mouse Primary Hepatocytes

Effects of 8-methoxypsoralen on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice

Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver

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