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Resveratrol attenuates angiotensin II-induced cellular hypertrophy through the inhibition of CYP1B1 and the cardiotoxic mid-chain HETE metabolites

Molecular and cellular biochemistry, 2020-08, Vol.471 (1-2), p.165-176

2020

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CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation

PloS one, 2016-03, Vol.11 (3), p.e0151598

2016

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Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3683-3687

2017

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A new class of CYP1B1 inhibitors derived from bentranil

Bioorganic & medicinal chemistry letters, 2023-01, Vol.80, p.129112-129112, Article 129112

2023

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Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors

European journal of medicinal chemistry, 2021-01, Vol.209, p.112895-112895, Article 112895

2021

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Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors

European journal of medicinal chemistry, 2020-02, Vol.187, p.111938, Article 111938

2020

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Inhibitors of cytochrome P450 (CYP) 1B1

European journal of medicinal chemistry, 2017-07, Vol.135, p.296-306

2017

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Human CYP1B1 enzyme-mediated, AhR enhanced activation of aflatoxin B1 for its genotoxicity in human cells

Toxicology letters, 2023-01, Vol.373, p.132-140

2023

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Variable Phenotype of Congenital Corneal Opacities in Biallelic CYP1B1 Pathogenic Variants

Cornea, 2024-02, Vol.43 (2), p.195

2024

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Nature communications, 2018-11, Vol.9 (1), p.4774-10, Article 4774

2018

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WY-14643 Regulates CYP1B1 Expression through Peroxisome Proliferator-Activated Receptor α-Mediated Signaling in Human Breast Cancer Cells

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5928

2019

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Potential role of CYP1B1 in the development and treatment of metabolic diseases

Pharmacology & therapeutics (Oxford), 2017-10, Vol.178, p.18-30

2017

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MicroRNA-187-5p suppresses cancer cell progression in non-small cell lung cancer (NSCLC) through down-regulation of CYP1B1

Biochemical and biophysical research communications, 2016-09, Vol.478 (2), p.649-655

2016

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Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis

Free radical biology & medicine, 2017-11, Vol.112, p.452-463

2017

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Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance

European journal of medicinal chemistry, 2024-06, Vol.272, p.116488-116488, Article 116488

2024

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Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons

Environmental research, 2016-11, Vol.151, p.106-114

2016

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Potential role of aryl hydrocarbon receptor signaling in childhood obesity

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-08, Vol.1865 (8), p.158714-158714, Article 158714

2020

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Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

Oncotarget, 2017-06, Vol.8 (24), p.39087-39100

2017

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Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability

The Journal of biological chemistry, 2020-04, Vol.295 (17), p.5640-5653

2020

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Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach

PeerJ (San Francisco, CA), 2022-11, Vol.10, p.e14132, Article e14132

2022

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CGH array for the identification of a compound heterozygous mutation in the CYP1B1 gene in a patient with bilateral anterior segment dysgenesis

Clinical chemistry and laboratory medicine, 2019-04, Vol.57 (4), p.e63

2019

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Quinazoline derivatives as selective CYP1B1 inhibitors

European journal of medicinal chemistry, 2017-04, Vol.130, p.320-327

2017

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Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects

Toxicological sciences, 2021-02, Vol.180 (1), p.148-159

2021

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Ultrastructural abnormalities of the trabecular meshwork extracellular matrix in Cyp1b1-deficient mice

Veterinary pathology, 2015-03, Vol.52 (2), p.397

2015

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Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway

Investigative ophthalmology & visual science, 2017-02, Vol.58 (2), p.1084-1097

2017

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Resveratrol attenuates angiotensin II-induced cellular hypertrophy through the inhibition of CYP1B1 and the cardiotoxic mid-chain HETE metabolites

CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation

Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance

A new class of CYP1B1 inhibitors derived from bentranil

Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors

Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors

Inhibitors of cytochrome P450 (CYP) 1B1

Human CYP1B1 enzyme-mediated, AhR enhanced activation of aflatoxin B1 for its genotoxicity in human cells

Variable Phenotype of Congenital Corneal Opacities in Biallelic CYP1B1 Pathogenic Variants

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

WY-14643 Regulates CYP1B1 Expression through Peroxisome Proliferator-Activated Receptor α-Mediated Signaling in Human Breast Cancer Cells

Potential role of CYP1B1 in the development and treatment of metabolic diseases

MicroRNA-187-5p suppresses cancer cell progression in non-small cell lung cancer (NSCLC) through down-regulation of CYP1B1

Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis

Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance

Triclosan activates aryl hydrocarbon receptor (AhR)-dependent apoptosis and affects Cyp1a1 and Cyp1b1 expression in mouse neocortical neurons

Potential role of aryl hydrocarbon receptor signaling in childhood obesity

Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability

Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach

CGH array for the identification of a compound heterozygous mutation in the CYP1B1 gene in a patient with bilateral anterior segment dysgenesis

Quinazoline derivatives as selective CYP1B1 inhibitors

Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects

Ultrastructural abnormalities of the trabecular meshwork extracellular matrix in Cyp1b1-deficient mice

Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway

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