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Polarized macrophage functions are affected differentially after CSF-1R inhibition with PLX5622

European journal of pharmacology, 2024-10, Vol.984, p.177059, Article 177059

2024

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Remodeling tumor immune microenvironment via targeted blockade of PI3K-γ and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy

Journal of controlled release, 2020-05, Vol.321, p.23-35

2020

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Recent advances in colony stimulating factor-1 receptor/c-FMS as an emerging target for various therapeutic implications

Biomedicine & pharmacotherapy, 2018-07, Vol.103, p.662-679

2018

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Colony stimulating factor-1 receptor drives glomerular parietal epithelial cell activation in focal segmental glomerulosclerosis

Kidney international, 2024-07, Vol.106 (1), p.67-84

2024

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Time to heal: inhibiting fibrosis prevents glioblastoma recurrence

Trends in Cancer, 2024-10

2024

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Interleukin‐34, a comprehensive review

Journal of leukocyte biology, 2018-11, Vol.104 (5), p.931-951

2018

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Microglia Are Critical in Host Defense against Prion Disease

Journal of virology, 2018-08, Vol.92 (15)

2018

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Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

Frontiers in immunology, 2014-10, Vol.5, p.489-489

2014

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Colony stimulating factors in the nervous system

Seminars in immunology, 2021-04, Vol.54, p.101511-101511, Article 101511

2021

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Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance

Immunologic research, 2023-04, Vol.71 (2), p.130-152

2023

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IL‐34 and CSF‐1, deciphering similarities and differences at steady state and in diseases

Journal of leukocyte biology, 2021-10, Vol.110 (4), p.771-796

2021

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IL-34, the rationale for its expression in physiological and pathological conditions

Seminars in immunology, 2021-04, Vol.54, p.101517-101517, Article 101517

2021

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Macrophages: The Road Less Traveled, Changing Anticancer Therapy

Trends in molecular medicine, 2018-05, Vol.24 (5), p.472-489

Guerriero, Jennifer L.

2018

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Discovery of N-(5-amido-2-methylphenyl)-5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability

European journal of medicinal chemistry, 2024-03, Vol.268, p.116253-116253, Article 116253

2024

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Discovery of a CSF-1R inhibitor and PET tracer for imaging of microglia and macrophages in the brain

Nuclear medicine and biology, 2022-11, Vol.114-115, p.99-107

2022

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Modeling CSF‐1 receptor deficiency diseases – how close are we?

The FEBS journal, 2022-09, Vol.289 (17), p.5049-5073

2022

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Differentiated mesenchymal stem cells-derived exosomes immobilized in decellularized sciatic nerve hydrogels for peripheral nerve repair

Journal of controlled release, 2024-04, Vol.368, p.24-41

2024

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Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages

Annals of oncology, 2019-08, Vol.30 (8), p.1381-1392

2019

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PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production

Frontiers in immunology, 2022-03, Vol.13, p.851556-851556

2022

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Inhibition of Colony-Stimulating Factor-1 Receptor Enhances the Efficacy of Radiotherapy and Reduces Immune Suppression in Glioblastoma

In vivo (Athens), 2021-01, Vol.35 (1), p.119-129

2021

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Azithromycin alters Colony Stimulating Factor-1R (CSF-1R) expression and functional output of murine bone marrow-derived macrophages: A novel report

International immunopharmacology, 2023-10, Vol.123, p.110688-110688, Article 110688

2023

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Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase

European journal of medicinal chemistry, 2024-08, Vol.274, p.116557, Article 116557

2024

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Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy

Acta neuropathologica communications, 2020-05, Vol.8 (1), p.72-72, Article 72

2020

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Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model

Frontiers in oncology, 2023-10, Vol.13, p.1263873-1263873

2023

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The latest perspectives of small molecules FMS kinase inhibitors

European journal of medicinal chemistry, 2023-12, Vol.261, p.115796, Article 115796

2023

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Polarized macrophage functions are affected differentially after CSF-1R inhibition with PLX5622

Remodeling tumor immune microenvironment via targeted blockade of PI3K-γ and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy

Recent advances in colony stimulating factor-1 receptor/c-FMS as an emerging target for various therapeutic implications

Colony stimulating factor-1 receptor drives glomerular parietal epithelial cell activation in focal segmental glomerulosclerosis

Time to heal: inhibiting fibrosis prevents glioblastoma recurrence

Interleukin‐34, a comprehensive review

Microglia Are Critical in Host Defense against Prion Disease

Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

Colony stimulating factors in the nervous system

Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance

IL‐34 and CSF‐1, deciphering similarities and differences at steady state and in diseases

IL-34, the rationale for its expression in physiological and pathological conditions

Macrophages: The Road Less Traveled, Changing Anticancer Therapy

Discovery of N-(5-amido-2-methylphenyl)-5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability

Discovery of a CSF-1R inhibitor and PET tracer for imaging of microglia and macrophages in the brain

Modeling CSF‐1 receptor deficiency diseases – how close are we?

Differentiated mesenchymal stem cells-derived exosomes immobilized in decellularized sciatic nerve hydrogels for peripheral nerve repair

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages

PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production

Inhibition of Colony-Stimulating Factor-1 Receptor Enhances the Efficacy of Radiotherapy and Reduces Immune Suppression in Glioblastoma

Azithromycin alters Colony Stimulating Factor-1R (CSF-1R) expression and functional output of murine bone marrow-derived macrophages: A novel report

Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase

Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy

Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model

The latest perspectives of small molecules FMS kinase inhibitors

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