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Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer

Biochemical and biophysical research communications, 2018-05, Vol.499 (2), p.156-163

2018

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Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway

Biochemical pharmacology, 2018-04, Vol.150, p.191-201

2018

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Structure Basis of Bigelovin as a Selective RXR Agonist with a Distinct Binding Mode

Journal of molecular biology, 2011-03, Vol.407 (1), p.13-20

2011

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Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells

Acta pharmacologica Sinica, 2015-04, Vol.36 (4), p.507-516

2015

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Apoptosis inducement of bigelovin from Inula helianthus-aquatica on human Leukemia U937 cells

Phytotherapy research, 2009-06, Vol.23 (6), p.885-891

2009

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Nuclear factor kappaB-mediated down-regulation of adhesion molecules: Possible mechanism for inhibitory activity of bigelovin against inflammatory monocytes adhesion to endothelial cells

Journal of ethnopharmacology, 2009-06, Vol.123 (2), p.250-256

2009

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Simultaneous determination of three sesquiterpene lactones in Inula hupehensis by RP-HPLC

Zhongguo zhongyao zazhi, 2011-09, Vol.36 (18), p.2520

2011

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Oxidation of britanin

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2000-07, Vol.36 (7), p.870-871

2000

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Pseudoguaianolides isolated from Inula britannica var. chinenis as inhibitory constituents against inducible nitric oxide synthase

Archives of pharmacal research, 2002-04, Vol.25 (2), p.151-153

2002

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Anti-emetic principles of Inula linariaefolia flowers and Forsythia suspensa fruits

Phytomedicine (Stuttgart), 1996-05, Vol.3 (1), p.51-58

1996

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Cytotoxicity and NMR spectral assignments of ergolide and bigelovin

Planta medica, 1996-04, Vol.62 (2), p.166-168

1996

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Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer

Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway

Structure Basis of Bigelovin as a Selective RXR Agonist with a Distinct Binding Mode

Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells

Apoptosis inducement of bigelovin from Inula helianthus-aquatica on human Leukemia U937 cells

Nuclear factor kappaB-mediated down-regulation of adhesion molecules: Possible mechanism for inhibitory activity of bigelovin against inflammatory monocytes adhesion to endothelial cells

Simultaneous determination of three sesquiterpene lactones in Inula hupehensis by RP-HPLC

Oxidation of britanin

Pseudoguaianolides isolated from Inula britannica var. chinenis as inhibitory constituents against inducible nitric oxide synthase

Anti-emetic principles of Inula linariaefolia flowers and Forsythia suspensa fruits

Cytotoxicity and NMR spectral assignments of ergolide and bigelovin

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