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Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.10030-10044

2020

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Therapeutic evolution of benzimidazole derivatives in the last quinquennial period

European journal of medicinal chemistry, 2017-01, Vol.126, p.705-753

2017

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Benzimidazoles in Drug Discovery: A Patent Review

ChemMedChem, 2021-06, Vol.16 (12), p.1861-1877

2021

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The therapeutic journey of benzimidazoles: A review

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (21), p.6208-6236

2012

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Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation

European journal of medicinal chemistry, 2018-01, Vol.143, p.66-84

2018

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Isocitrate Dehydrogenase Mutation and (R)-2-Hydroxyglutarate: From Basic Discovery to Therapeutics Development

Annual review of biochemistry, 2017-06, Vol.86 (1), p.305-331

2017

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Solvent/Oxidant-Switchable Synthesis of Multisubstituted Quinazolines and Benzimidazoles via Metal-Free Selective Oxidative Annulation of Arylamidines

Organic letters, 2014-06, Vol.16 (11), p.2822-2825

2014

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Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Nature chemical biology, 2015-03, Vol.11 (3), p.189-191

2015

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Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents

European journal of medicinal chemistry, 2016-11, Vol.124, p.608-621

2016

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Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole

European journal of medicinal chemistry, 2014-04, Vol.77, p.1-7

2014

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Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5518-5528

2012

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Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents

European journal of medicinal chemistry, 2016-10, Vol.122, p.205-215

2016

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A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles from N-Aryl-2-aminopyridines

Journal of the American Chemical Society, 2010-09, Vol.132 (38), p.13217-13219

2010

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Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3259

2019

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Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria

European journal of medicinal chemistry, 2020-01, Vol.186, p.111850-111850, Article 111850

2020

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Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent

Bioorganic chemistry, 2020-03, Vol.96, p.103576, Article 103576

Rashid, Mohammad

2020

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Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

European journal of medicinal chemistry, 2017-05, Vol.131, p.255-262

2017

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Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7310-7327

2015

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3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies

European journal of medicinal chemistry, 2020-12, Vol.207, p.112745, Article 112745

2020

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Convenient Synthesis of Benzothiazoles and Benzimidazoles through Brønsted Acid Catalyzed Cyclization of 2‑Amino Thiophenols/Anilines with β‑Diketones

Organic letters, 2014-02, Vol.16 (3), p.764-767

2014

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From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N‑Heterocyclic-Carbene Complexes as Anticancer Agents

Inorganic chemistry, 2018-11, Vol.57 (22), p.14427-14434

2018

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Design, Synthesis, and Biological Evaluation of Amidobenzimidazole Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.260-282

2020

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Gold nanoparticles supported on titanium dioxide: an efficient catalyst for highly selective synthesis of benzoxazoles and benzimidazoles

Chemical communications (Cambridge, England), 2014-01, Vol.50 (46), p.6145-6148

2014

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In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives

European journal of medicinal chemistry, 2010-05, Vol.45 (5), p.2048-2054

2010

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Synthesis and anticancer activity of some novel 2-substituted benzimidazole derivatives

European journal of medicinal chemistry, 2010-07, Vol.45 (7), p.2949-2956

Refaat, Hanan M.

2010

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Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor

Therapeutic evolution of benzimidazole derivatives in the last quinquennial period

Benzimidazoles in Drug Discovery: A Patent Review

The therapeutic journey of benzimidazoles: A review

Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation

Isocitrate Dehydrogenase Mutation and (R)-2-Hydroxyglutarate: From Basic Discovery to Therapeutics Development

Solvent/Oxidant-Switchable Synthesis of Multisubstituted Quinazolines and Benzimidazoles via Metal-Free Selective Oxidative Annulation of Arylamidines

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents

Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole

Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents

Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents

A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles from N-Aryl-2-aminopyridines

Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents

Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria

Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent

Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies

Convenient Synthesis of Benzothiazoles and Benzimidazoles through Brønsted Acid Catalyzed Cyclization of 2‑Amino Thiophenols/Anilines with β‑Diketones

From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N‑Heterocyclic-Carbene Complexes as Anticancer Agents

Design, Synthesis, and Biological Evaluation of Amidobenzimidazole Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists

Gold nanoparticles supported on titanium dioxide: an efficient catalyst for highly selective synthesis of benzoxazoles and benzimidazoles

In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives

Synthesis and anticancer activity of some novel 2-substituted benzimidazole derivatives

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