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Perfluoroarene–Based Peptide Macrocycles to Enhance Penetration Across the Blood–Brain Barrier

Journal of the American Chemical Society, 2017-11, Vol.139 (44), p.15628-15631

2017

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SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation

Cancer research (Chicago, Ill.), 2021-11, Vol.81 (21), p.5451-5463

2021

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Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance

Leukemia, 2021-10, Vol.35 (10), p.2862-2874

2021

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Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim

The Journal of biological chemistry, 2018-04, Vol.293 (15), p.5464-5477

2018

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The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

ACS chemical biology, 2017-05, Vol.12 (5), p.1297-1307

2017

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The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis

EMBO reports, 2016-05, Vol.17 (5), p.724-738

2016

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The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils

Cellular and molecular life sciences : CMLS, 2021-03, Vol.78 (5), p.2145-2155

2021

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Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization

Apoptosis (London), 2020-04, Vol.25 (3-4), p.247-260

2020

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Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer

Cell death and differentiation, 2016-09, Vol.23 (9), p.1483-1492

2016

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Cell cycle dependence of apoptosis photo-triggered using peptide-photosensitizer conjugate

Scientific reports, 2020-11, Vol.10 (1), p.19087, Article 19087

2020

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Mouse ER+/PIK3CA H1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents

Oncogene, 2019-01, Vol.38 (1), p.47-59

2019

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Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins

Oncogene, 2017-08, Vol.36 (35), p.4953-4962

2017

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Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53

Cell cycle (Georgetown, Tex.), 2016-02, Vol.15 (3), p.394-402

2016

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The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.25207-25216

2016

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MiR-24 alleviates cardiomyocyte apoptosis after myocardial infarction via targeting BIM

European review for medical and pharmacological sciences, 2017-07, Vol.21 (13), p.3088

2017

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DMFC (3,5-dimethyl-7H-furo[3,2-g]chromen-7-one) regulates Bim to trigger Bax and Bak activation to suppress drug-resistant human hepatoma

Apoptosis (London), 2017-03, Vol.22 (3), p.381-392

2017

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The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

Nature (London), 2016-09, Vol.537 (7619), p.239-243

2016

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BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors

Cell death & disease, 2016-04, Vol.7 (4), p.e2177-e2177

2016

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Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy

Medical science monitor, 2017-07, Vol.23, p.3603-3616

2017

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IL‐2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

Immunity, Inflammation and Disease, 2019-09, Vol.7 (3), p.112-124

2019

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Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia

Leukemia, 2017-10, Vol.31 (10), p.2075-2084

2017

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Anticancer activity of Ashwagandha against human head and neck cancer cell lines

Journal of oral pathology & medicine, 2016-03, Vol.45 (3), p.193-201

2016

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Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation

Clinical cancer research, 2017-11, Vol.23 (21), p.6567-6579

2017

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Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design

Molecular cell, 2017-11, Vol.68 (4), p.659-672.e9

2017

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LncRNA HAND2‐AS1 exerts anti‐oncogenic effects on ovarian cancer via restoration of BCL2L11 as a sponge of microRNA‐340‐5p

Journal of cellular physiology, 2019-12, Vol.234 (12), p.23421-23436

2019

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Perfluoroarene–Based Peptide Macrocycles to Enhance Penetration Across the Blood–Brain Barrier

SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation

Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance

Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis

The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization

Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer

Cell cycle dependence of apoptosis photo-triggered using peptide-photosensitizer conjugate

Mouse ER+/PIK3CA H1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents

Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins

Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53

The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes

MiR-24 alleviates cardiomyocyte apoptosis after myocardial infarction via targeting BIM

DMFC (3,5-dimethyl-7H-furo[3,2-g]chromen-7-one) regulates Bim to trigger Bax and Bak activation to suppress drug-resistant human hepatoma

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors

Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy

IL‐2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia

Anticancer activity of Ashwagandha against human head and neck cancer cell lines

Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation

Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design

LncRNA HAND2‐AS1 exerts anti‐oncogenic effects on ovarian cancer via restoration of BCL2L11 as a sponge of microRNA‐340‐5p

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