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Myricetin Acts as an Inhibitor of Type II NADH Dehydrogenase from Staphylococcus aureus

Molecules (Basel, Switzerland), 2024-05, Vol.29 (10), p.2354

2024

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Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins

Nature communications, 2024-04, Vol.15 (1), p.3537-3537, Article 3537

2024

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KcsA-Kv1.x chimeras with complete ligand-binding sites provide improved predictivity for screening selective Kv1.x blockers

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107155-107155, Article 107155

2024

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The evolutionary divergence of receptor guanylyl cyclase C has implications for preclinical models for receptor-directed therapeutics

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105505-105505, Article 105505

2024

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In Silico and In Vitro Investigation of Phytochemicals Against Shrimp AHPND Syndrome Causing PirA/B Toxins of Vibrio parahaemolyticus

Applied biochemistry and biotechnology, 2023-12, Vol.195 (12), p.7176-7196

2023

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C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation

Nature (London), 2023-10, Vol.622 (7983), p.611-618

2023

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In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A

ACS chemical biology, 2022-01, Vol.17 (1), p.118-128

2022

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Halogen‐Dance‐Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2‐Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases

ChemMedChem, 2022-01, Vol.17 (1), p.e202100568-n/a

2022

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Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues

Nature communications, 2021-11, Vol.12 (1), p.6285-6285, Article 6285

2021

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Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases

European journal of medicinal chemistry, 2021-10, Vol.222, p.113581-113581, Article 113581

2021

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Multimodal Molecular Imaging and Identification of Bacterial Toxins Causing Mushroom Soft Rot and Cavity Disease

Chembiochem : a European journal of chemical biology, 2021-10, Vol.22 (19), p.2901-2907

2021

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Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments

Toxins, 2021-09, Vol.13 (10), p.677

2021

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Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers

Cell chemical biology, 2021-09, Vol.28 (9), p.1310-1320.e5

2021

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The Innate Immune Glycoprotein Lactoferrin Represses the Helicobacter pylori cag Type IV Secretion System

Chembiochem : a European journal of chemical biology, 2021-09, Vol.22 (18), p.2783-2790

2021

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Polycyclic polyprenylated acylphloroglucinol congeners from Garcinia yunnanensis Hu with inhibitory effect on α-hemolysin production in Staphylococcus aureus

Bioorganic chemistry, 2021-09, Vol.114, p.105074-105074, Article 105074

2021

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Toxin Induction or Inhibition of Transcription or Translation Posttreatment Increases Persistence to Fluoroquinolones

mBio, 2021-08, Vol.12 (4), p.e0198321

2021

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Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions

Toxins, 2021-07, Vol.13 (8), p.520

2021

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Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin

Toxins, 2021-07, Vol.13 (7), p.480

2021

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Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach

American journal of medical genetics. Part A, 2021-07, Vol.185 (7), p.2046-2055

2021

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Catalase inhibition by nitric oxide potentiates hydrogen peroxide to trigger catastrophic chromosome fragmentation in Escherichia coli

Genetics (Austin), 2021-06, Vol.218 (2)

2021

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Soluble Cytoplasmic Expression and Purification of Immunotoxin HER2(scFv)-PE24B as a Maltose Binding Protein Fusion

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6483

2021

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Pseudomonas Exotoxin A‑Based Immunotherapy Targeting CCK2R-Expressing Colorectal Malignancies: An In Vitro and In Vivo Evaluation

Molecular pharmaceutics, 2021-06, Vol.18 (6), p.2285-2297

2021

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Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages

Journal of medical microbiology, 2021-04, Vol.70 (4)

2021

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The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2926

2021

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Epigallocatechin gallate alters leukotoxin secretion and Aggregatibacter actinomycetemcomitans virulence

Journal of pharmacy and pharmacology, 2021-03, Vol.73 (4), p.505-514

2021

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Myricetin Acts as an Inhibitor of Type II NADH Dehydrogenase from Staphylococcus aureus

Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins

KcsA-Kv1.x chimeras with complete ligand-binding sites provide improved predictivity for screening selective Kv1.x blockers

The evolutionary divergence of receptor guanylyl cyclase C has implications for preclinical models for receptor-directed therapeutics

In Silico and In Vitro Investigation of Phytochemicals Against Shrimp AHPND Syndrome Causing PirA/B Toxins of Vibrio parahaemolyticus

C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation

In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A

Halogen‐Dance‐Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2‐Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases

Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues

Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases

Multimodal Molecular Imaging and Identification of Bacterial Toxins Causing Mushroom Soft Rot and Cavity Disease

Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments

Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers

The Innate Immune Glycoprotein Lactoferrin Represses the Helicobacter pylori cag Type IV Secretion System

Polycyclic polyprenylated acylphloroglucinol congeners from Garcinia yunnanensis Hu with inhibitory effect on α-hemolysin production in Staphylococcus aureus

Toxin Induction or Inhibition of Transcription or Translation Posttreatment Increases Persistence to Fluoroquinolones

Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions

Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin

Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach

Catalase inhibition by nitric oxide potentiates hydrogen peroxide to trigger catastrophic chromosome fragmentation in Escherichia coli

Soluble Cytoplasmic Expression and Purification of Immunotoxin HER2(scFv)-PE24B as a Maltose Binding Protein Fusion

Pseudomonas Exotoxin A‑Based Immunotherapy Targeting CCK2R-Expressing Colorectal Malignancies: An In Vitro and In Vivo Evaluation

Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages

The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile

Epigallocatechin gallate alters leukotoxin secretion and Aggregatibacter actinomycetemcomitans virulence

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