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Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization

Biochemical pharmacology, 2024-02, Vol.220, p.116013-116013, Article 116013

2024

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Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Nature communications, 2019-03, Vol.10 (1), p.1261-1261, Article 1261

2019

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Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin

Proceedings of the National Academy of Sciences - PNAS, 2023-10, Vol.120 (43), p.e2303794120-e2303794120

2023

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The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation

Biochemical pharmacology, 2024-04, Vol.222, p.116119-116119, Article 116119

2024

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Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

Science signaling, 2023-04, Vol.16 (779), p.eabl4283

2023

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Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105293, Article 105293

2023

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Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers

EMBO reports, 2020-11, Vol.21 (11), p.e50437-n/a

2020

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Carfentanil is a β‐arrestin‐biased agonist at the μ opioid receptor

British journal of pharmacology, 2023-09, Vol.180 (18), p.2341-2360

2023

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Conformational Dynamics and Functional Implications of Phosphorylated β-Arrestins

Structure (London), 2020-03, Vol.28 (3), p.314-323.e3

2020

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Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

Cell, 2022-11, Vol.185 (24), p.4560-4573.e19

2022

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Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by β-arrestins

PloS one, 2019-07, Vol.14 (7), p.e0219011-e0219011

2019

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Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

Nature (London), 2013-05, Vol.497 (7447), p.137-141

2013

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miR-374a-5p promotes tumor progression by targeting ARRB1 in triple negative breast cancer

Cancer letters, 2019-07, Vol.454, p.224-233

2019

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Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

Nature communications, 2021-04, Vol.12 (1), p.2396-16, Article 2396

2021

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Lack of beta-arrestin signaling in the absence of active G proteins

Nature communications, 2018-01, Vol.9 (1), p.341-16, Article 341

2018

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Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Nature (London), 2020-03, Vol.579 (7798), p.303-308

2020

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Insights Into the Role of Angiotensin-II AT 1 Receptor-Dependent β-Arrestin Signaling in Cardiovascular Disease

Hypertension (Dallas, Tex. 1979), 2024-01, Vol.81 (1), p.6-16

2024

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GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation

Nature communications, 2022-01, Vol.13 (1), p.540-540, Article 540

2022

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Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide

Structure (London), 2020-09, Vol.28 (9), p.1014-1023.e4

2020

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GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision

Cell, 2022-05, Vol.185 (10), p.1661-1675.e16

2022

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Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling

European journal of pharmacology, 2024-04, Vol.968, p.176419-176419, Article 176419

2024

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β-arrestin signaling and regulation of transcription

Journal of cell science, 2007-01, Vol.120 (2), p.213-218

2007

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Disrupted circadian expression of β‐arrestin 2 affects reward‐related µ‐opioid receptor function in alcohol dependence

Journal of neurochemistry, 2022-02, Vol.160 (4), p.454-468

2022

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β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling

Oncogene, 2013-10, Vol.32 (42), p.5066-5077

2013

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β-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signalling

Cardiovascular research, 2017-11, Vol.113 (13), p.1615-1626

2017

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Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin

The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation

Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor

Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers

Carfentanil is a β‐arrestin‐biased agonist at the μ opioid receptor

Conformational Dynamics and Functional Implications of Phosphorylated β-Arrestins

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

Regulation of cardiac fibroblast-mediated maladaptive ventricular remodeling by β-arrestins

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

miR-374a-5p promotes tumor progression by targeting ARRB1 in triple negative breast cancer

Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

Lack of beta-arrestin signaling in the absence of active G proteins

Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Insights Into the Role of Angiotensin-II AT 1 Receptor-Dependent β-Arrestin Signaling in Cardiovascular Disease

GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation

Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide

GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision

Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling

β-arrestin signaling and regulation of transcription

Disrupted circadian expression of β‐arrestin 2 affects reward‐related µ‐opioid receptor function in alcohol dependence

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling

β-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signalling

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