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Engineered immune cells as highly sensitive cancer diagnostics

Nature biotechnology, 2019-05, Vol.37 (5), p.531-539

2019

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Autophagy maintains tumour growth through circulating arginine

Nature (London), 2018-11, Vol.563 (7732), p.569-573

2018

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Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity

The Journal of clinical investigation, 2021-03, Vol.131 (6), p.1-14

2021

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Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

International journal of cancer, 2019-10, Vol.145 (8), p.2201-2208

2019

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Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency

Journal of inherited metabolic disease, 2021-07, Vol.44 (4), p.847-856

2021

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Arginase-1-dependent promotion of TH17 differentiation and disease progression by MDSCs in systemic lupus erythematosus

Science translational medicine, 2016-03, Vol.8 (331), p.331ra40

2016

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Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients

Critical care (London, England), 2014-08, Vol.18 (4), p.R163-R163

2014

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Arginase I, Polyamine, and Prostaglandin E₂ Pathways Suppress the Inflammatory Response and Contribute to Diffuse Cutaneous Leishmaniasis

The Journal of infectious diseases, 2015-02, Vol.211 (3), p.426-435

2015

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Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.15049-15054

2013

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Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples

Journal of immunological methods, 2012-07, Vol.381 (1-2), p.14-22

2012

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Immune off‐target effects of Brentuximab Vedotin in relapsed/refractory Hodgkin Lymphoma

British journal of haematology, 2019-05, Vol.185 (3), p.468-479

2019

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Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency

Human molecular genetics, 2015-11, Vol.24 (22), p.6417-6427

2015

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Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis

Arthritis research & therapy, 2018-06, Vol.20 (1), p.123-123, Article 123

2018

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Arginase 1 is upregulated at admission in patients with ST‐elevation myocardial infarction

Journal of internal medicine, 2021-11, Vol.290 (5), p.1061-1070

2021

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Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease

JAMA : the journal of the American Medical Association, 2005-07, Vol.294 (1), p.81

2005

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Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

mBio, 2021-10, Vol.12 (5), p.e0242421-e0242421

2021

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Arginase inhibition alleviates hypertension in the metabolic syndrome

British journal of pharmacology, 2013-06, Vol.169 (3), p.693-703

2013

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A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report

Medicine (Baltimore), 2020-08, Vol.99 (32), p.e21634

2020

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Myeloid Diagnostic and Prognostic Markers of Immune Suppression in the Blood of Glioma Patients

Frontiers in immunology, 2022-01, Vol.12, p.809826-809826

2022

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Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4699-4713

2015

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Association between arginase-containing platelet-derived microparticles and altered plasma arginine metabolism in polycystic ovary syndrome

Metabolism, clinical and experimental, 2019-01, Vol.90, p.16-19

2019

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Arginase I Release from Activated Neutrophils Induces Peripheral Immunosuppression in a Murine Model of Stroke

Journal of cerebral blood flow and metabolism, 2015-10, Vol.35 (10), p.1657-1663

2015

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Influence of arginase polymorphisms and arginase levels/activity on the response to erectile dysfunction therapy with sildenafil

The pharmacogenomics journal, 2018-04, Vol.18 (2), p.238-244

2018

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Effectiveness of arginase inhibitors against experimentally induced stroke

Naunyn-Schmiedeberg's archives of pharmacology, 2018-06, Vol.391 (6), p.603-612

2018

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LncRNA AK036396 Inhibits Maturation and Accelerates Immunosuppression of Polymorphonuclear Myeloid-Derived Suppressor Cells by Enhancing the Stability of Ficolin B

Cancer immunology research, 2020-04, Vol.8 (4), p.565-577

2020

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Engineered immune cells as highly sensitive cancer diagnostics

Autophagy maintains tumour growth through circulating arginine

Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity

Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency

Arginase-1-dependent promotion of TH17 differentiation and disease progression by MDSCs in systemic lupus erythematosus

Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients

Arginase I, Polyamine, and Prostaglandin E₂ Pathways Suppress the Inflammatory Response and Contribute to Diffuse Cutaneous Leishmaniasis

Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity

Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples

Immune off‐target effects of Brentuximab Vedotin in relapsed/refractory Hodgkin Lymphoma

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency

Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis

Arginase 1 is upregulated at admission in patients with ST‐elevation myocardial infarction

Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease

Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

Arginase inhibition alleviates hypertension in the metabolic syndrome

A novel compound heterozygous mutation in the arginase-1 gene identified in a Chinese patient with argininemia: A case report

Myeloid Diagnostic and Prognostic Markers of Immune Suppression in the Blood of Glioma Patients

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis

Association between arginase-containing platelet-derived microparticles and altered plasma arginine metabolism in polycystic ovary syndrome

Arginase I Release from Activated Neutrophils Induces Peripheral Immunosuppression in a Murine Model of Stroke

Influence of arginase polymorphisms and arginase levels/activity on the response to erectile dysfunction therapy with sildenafil

Effectiveness of arginase inhibitors against experimentally induced stroke

LncRNA AK036396 Inhibits Maturation and Accelerates Immunosuppression of Polymorphonuclear Myeloid-Derived Suppressor Cells by Enhancing the Stability of Ficolin B

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