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Magnoflorine: A review of its pharmacology, pharmacokinetics and toxicity

Pharmacological research, 2020-02, Vol.152, p.104632, Article 104632

2020

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Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS

Journal of pharmaceutical and biomedical analysis, 2020-01, Vol.177, p.112836, Article 112836

2020

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Natural aporphine alkaloids: A comprehensive review of phytochemistry, pharmacokinetics, anticancer activities, and clinical application

Journal of advanced research, 2024-09, Vol.63, p.231-253

2024

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HPLC–MS/MS method for the determination and pharmacokinetic study of six compounds against rheumatoid arthritis in rat plasma after oral administration of the extract of Caulophyllum robustum Maxim

Journal of pharmaceutical and biomedical analysis, 2020-03, Vol.181, p.112923, Article 112923

2020

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Establishment of modified biopharmaceutics classification system absorption model for oral Traditional Chinese Medicine (Sanye Tablet)

Journal of ethnopharmacology, 2019-11, Vol.244, p.112148-112148, Article 112148

2019

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Pharmacokinetics, tissue distribution and excretion of 6-O-demethylmenisporphine, a bioactive oxoisoaporphine alkaloid from Menispermi Rhizoma, as determined by a HPLC-MS/MS method

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-11, Vol.1156, p.122297-122297, Article 122297

2020

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Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers

Scientific reports, 2015-08, Vol.5 (1), p.12961, Article 12961

2015

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In vitro and in vivo identification of metabolites of magnoflorine by LC LTQ-Orbitrap MS and its potential pharmacokinetic interaction in Coptidis Rhizoma decoction in rat

Biomedical chromatography, 2015-08, Vol.29 (8), p.1235-1248

2015

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Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

Pharmaceutical biology, 2021-01, Vol.59 (1), p.882-890

2021

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Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors

European journal of medicinal chemistry, 2011-10, Vol.46 (10), p.4970-4979

2011

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A sensitive liquid chromatography–tandem mass spectrometry method for pharmacokinetics and tissue distribution of nuciferine in rats

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-06, Vol.961, p.20-28

2014

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Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes

Journal of cardiovascular pharmacology, 2015-06, Vol.65 (6), p.522-531

2015

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Preparation, pharmacokinetics and anti‐obesity effects on dogs of nuciferine liposomes

Veterinary medicine and science, 2024-09, Vol.10 (5), p.e70017-n/a

2024

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Study on the PK profiles of magnoflorine and its potential interaction in Cortex phellodendri decoction by LC-MS/MS

Analytical and bioanalytical chemistry, 2014-01, Vol.406 (3), p.841-849

2014

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Studies on the in vivo contribution of human cytochrome P450s to the hepatic metabolism of glaucine, a new drug of abuse

Biochemical pharmacology, 2013-11, Vol.86 (10), p.1497-1506

2013

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Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-10, Vol.936, p.48-56

2013

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Pharmacokinetics of boldine in control and Mrp2-deficient rats

Physiological research, 2016-01, Vol.65 (Suppl 4), p.S489-S497

2016

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In Vitro Intestinal Absorption and Metabolism of Magnoflorine and its Potential Interaction in Coptidis Rhizoma Decoction in Rat

European journal of drug metabolism and pharmacokinetics, 2017-04, Vol.42 (2), p.281-293

2017

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The active ingredients of Jiang-Zhi-Ning: study of the Nelumbo nucifera alkaloids and their main bioactive metabolites

Molecules (Basel, Switzerland), 2012-08, Vol.17 (8), p.9855-9867

2012

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A novel UPLC-MS/MS method for sensitive quantitation of boldine in plasma, a potential anti-inflammatory agent: application to a pharmacokinetic study in rats

Biomedical chromatography, 2015-03, Vol.29 (3), p.459-464

2015

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Rapid determination of isocorydine in rat plasma and tissues using liquid chromatography - tandem mass spectrometry and its applications to pharmacokinetics and tissue distribution

Xenobiotica, 2012-05, Vol.42 (5), p.466-476

2012

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Metabolism of dicentrine: identification of the phase I and phase II metabolites in miniature pig urine

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1714-1722

2010

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Orthogonal array design for optimization of hollow-fiber-based liquid-phase microextraction combined with high-performance liquid chromatography for study of the pharmacokinetics of magnoflorine in rat plasma

Analytical and bioanalytical chemistry, 2012-06, Vol.403 (7), p.1951-1960

2012

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Development and validation of a high-performance liquid chromatography coupled with ultraviolet detection method for the determination of isocorydine in rat plasma and its application in pharmacokinetics

Drug research (Stuttgart), 2013-11, Vol.63 (11), p.558-563

2013

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HPLC method for the pharmacokinetics and tissue distribution of taspine solution and taspine liposome after intravenous administrations to mice

Journal of pharmaceutical and biomedical analysis, 2008-01, Vol.46 (1), p.170-176

2008

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Magnoflorine: A review of its pharmacology, pharmacokinetics and toxicity

Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS

Natural aporphine alkaloids: A comprehensive review of phytochemistry, pharmacokinetics, anticancer activities, and clinical application

HPLC–MS/MS method for the determination and pharmacokinetic study of six compounds against rheumatoid arthritis in rat plasma after oral administration of the extract of Caulophyllum robustum Maxim

Establishment of modified biopharmaceutics classification system absorption model for oral Traditional Chinese Medicine (Sanye Tablet)

Pharmacokinetics, tissue distribution and excretion of 6-O-demethylmenisporphine, a bioactive oxoisoaporphine alkaloid from Menispermi Rhizoma, as determined by a HPLC-MS/MS method

Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers

In vitro and in vivo identification of metabolites of magnoflorine by LC LTQ-Orbitrap MS and its potential pharmacokinetic interaction in Coptidis Rhizoma decoction in rat

Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors

A sensitive liquid chromatography–tandem mass spectrometry method for pharmacokinetics and tissue distribution of nuciferine in rats

Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes

Preparation, pharmacokinetics and anti‐obesity effects on dogs of nuciferine liposomes

Study on the PK profiles of magnoflorine and its potential interaction in Cortex phellodendri decoction by LC-MS/MS

Studies on the in vivo contribution of human cytochrome P450s to the hepatic metabolism of glaucine, a new drug of abuse

Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Pharmacokinetics of boldine in control and Mrp2-deficient rats

In Vitro Intestinal Absorption and Metabolism of Magnoflorine and its Potential Interaction in Coptidis Rhizoma Decoction in Rat

The active ingredients of Jiang-Zhi-Ning: study of the Nelumbo nucifera alkaloids and their main bioactive metabolites

A novel UPLC-MS/MS method for sensitive quantitation of boldine in plasma, a potential anti-inflammatory agent: application to a pharmacokinetic study in rats

Rapid determination of isocorydine in rat plasma and tissues using liquid chromatography - tandem mass spectrometry and its applications to pharmacokinetics and tissue distribution

Metabolism of dicentrine: identification of the phase I and phase II metabolites in miniature pig urine

Orthogonal array design for optimization of hollow-fiber-based liquid-phase microextraction combined with high-performance liquid chromatography for study of the pharmacokinetics of magnoflorine in rat plasma

Development and validation of a high-performance liquid chromatography coupled with ultraviolet detection method for the determination of isocorydine in rat plasma and its application in pharmacokinetics

HPLC method for the pharmacokinetics and tissue distribution of taspine solution and taspine liposome after intravenous administrations to mice

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