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Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development

Clinical pharmacokinetics, 2009, Vol.48 (1), p.1-22

2009

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Population pharmacokinetics of human antithrombin concentrate in paediatric patients

British journal of clinical pharmacology, 2017-11, Vol.83 (11), p.2450-2457

2017

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Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Chest, 2012-02, Vol.141 (2 Suppl), p.e44S-e88S

2012

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Heparin-Induced Thrombocytopenia: A Comprehensive Clinical Review

Journal of the American College of Cardiology, 2016-05, Vol.67 (21), p.2519-2532

2016

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Bioequivalence of Two Intravenous Formulations of Antithrombin III: A Two-Way Crossover Study in Healthy Korean Subjects

Clinical therapeutics, 2013-11, Vol.35 (11), p.1752-1761

2013

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Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease

Thrombosis and haemostasis, 2013-04, Vol.109 (4), p.596

2013

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Laboratory and Clinical Monitoring of Direct Acting Oral Anticoagulants: What Clinicians Need to Know

Pharmacotherapy, 2017-02, Vol.37 (2), p.236-248

2017

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Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)

Stroke (1970), 2017-06, Vol.48 (6), p.1608-1616

2017

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Safety, tolerability and clinical pharmacology of dabigatran etexilate in adolescents. An open-label phase IIa study

Thrombosis and haemostasis, 2016-09, Vol.116 (3), p.461

2016

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Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate Oral Liquid Formulation in Infants with Venous Thromboembolism

Thrombosis and haemostasis, 2017-11, Vol.117 (11), p.2168

2017

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Impact of CytoSorb on kinetics of vancomycin and bivalirudin in critically ill patients

Artificial organs, 2021-09, Vol.45 (9), p.1097-1103

2021

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UNBLOCK: an open‐label, dose‐finding, pharmacokinetic and safety study of bivalirudin in children with deep vein thrombosis

Journal of thrombosis and haemostasis, 2015-09, Vol.13 (9), p.1615-1622

2015

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Impact of Non-Vitamin K Antagonist Oral Anticoagulants From a Basic Science Perspective

Arteriosclerosis, thrombosis, and vascular biology, 2017-10, Vol.37 (10), p.1812

2017

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Pharmacokinetics and Pharmacodynamics of Dabigatran 75 mg b.i.d. in Patients With Severe Chronic Kidney Disease

Journal of the American College of Cardiology, 2016-05, Vol.67 (20), p.2442-2444

2016

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Phase IIa study of dabigatran etexilate in children with venous thrombosis: pharmacokinetics, safety, and tolerability

Journal of thrombosis and haemostasis, 2017-11, Vol.15 (11), p.2147-2157

2017

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Measurement of dabigatran drug levels to manage patients taking interacting drugs: a case report

The American journal of medicine, 2016-10, Vol.129 (10), p.e247-e248

2016

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Transfer of Dabigatran and Dabigatran Etexilate Mesylate Across the Dually Perfused Human Placenta

Obstetrics and gynecology (New York. 1953), 2014-06, Vol.123 (6), p.1256-1261

2014

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Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis

Clinical pharmacokinetics, 2020-06, Vol.59 (6), p.809-825

2020

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Life-threatening bleeding in four patients with an unusual excessive response to dabigatran: implications for emergency surgery and resuscitation

Thrombosis and haemostasis, 2012-09, Vol.108 (3), p.583

2012

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Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia

Thrombosis and haemostasis, 2016-06, Vol.115 (6), p.1081

2016

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Dabigatran - Metabolism, Pharmacologic Properties and Drug Interactions

Current drug metabolism, 2017-01, Vol.18 (7), p.622

2017

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A semi‐mechanistic absorption model to evaluate drug–drug interaction with dabigatran: application with clarithromycin

British journal of clinical pharmacology, 2013-07, Vol.76 (1), p.107-113

2013

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Pharmacokinetics of dabigatran etexilate and rivaroxaban in patients with short bowel syndrome requiring parenteral nutrition: The PDER PAN study

Thrombosis research, 2017-12, Vol.160, p.76-82

2017

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Clinical Pharmacology Basis of Deriving Dosing Recommendations for Dabigatran in Patients With Severe Renal Impairment

Journal of clinical pharmacology, 2012-01, Vol.52 (S1), p.119S-125S

2012

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Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers

Circulation (New York, N.Y.), 2016-12, Vol.134 (23), p.1909-1911

2016

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Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development

Population pharmacokinetics of human antithrombin concentrate in paediatric patients

Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Heparin-Induced Thrombocytopenia: A Comprehensive Clinical Review

Bioequivalence of Two Intravenous Formulations of Antithrombin III: A Two-Way Crossover Study in Healthy Korean Subjects

Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease

Laboratory and Clinical Monitoring of Direct Acting Oral Anticoagulants: What Clinicians Need to Know

Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)

Safety, tolerability and clinical pharmacology of dabigatran etexilate in adolescents. An open-label phase IIa study

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate Oral Liquid Formulation in Infants with Venous Thromboembolism

Impact of CytoSorb on kinetics of vancomycin and bivalirudin in critically ill patients

UNBLOCK: an open‐label, dose‐finding, pharmacokinetic and safety study of bivalirudin in children with deep vein thrombosis

Impact of Non-Vitamin K Antagonist Oral Anticoagulants From a Basic Science Perspective

Pharmacokinetics and Pharmacodynamics of Dabigatran 75 mg b.i.d. in Patients With Severe Chronic Kidney Disease

Phase IIa study of dabigatran etexilate in children with venous thrombosis: pharmacokinetics, safety, and tolerability

Measurement of dabigatran drug levels to manage patients taking interacting drugs: a case report

Transfer of Dabigatran and Dabigatran Etexilate Mesylate Across the Dually Perfused Human Placenta

Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis

Life-threatening bleeding in four patients with an unusual excessive response to dabigatran: implications for emergency surgery and resuscitation

Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia

Dabigatran - Metabolism, Pharmacologic Properties and Drug Interactions

A semi‐mechanistic absorption model to evaluate drug–drug interaction with dabigatran: application with clarithromycin

Pharmacokinetics of dabigatran etexilate and rivaroxaban in patients with short bowel syndrome requiring parenteral nutrition: The PDER PAN study

Clinical Pharmacology Basis of Deriving Dosing Recommendations for Dabigatran in Patients With Severe Renal Impairment

Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers

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