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Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts

European journal of haematology, 2018-12, Vol.101 (6), p.711-720

2018

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GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia

Blood, 2015-01, Vol.125 (1), p.56-70

2015

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Telomerase gene therapy rescues telomere length, bone marrow aplasia, and survival in mice with aplastic anemia

Blood, 2016-04, Vol.127 (14), p.1770-1779

2016

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Iron toxicity – Its effect on the bone marrow

Blood reviews, 2018-11, Vol.32 (6), p.473-479

2018

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The complex pathophysiology of acquired aplastic anaemia

Clinical and experimental immunology, 2015-06, Vol.180 (3), p.361-370

2015

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Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia

The Journal of clinical investigation, 2022-02, Vol.132 (4), p.1-13

2022

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Hematopoietic stem progenitor cells lacking HLA differ from those lacking GPI-anchored proteins in the hierarchical stage and sensitivity to immune attack in patients with acquired aplastic anemia

Leukemia, 2021-11, Vol.35 (11), p.3257-3267

2021

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Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition

Biochimica et biophysica acta. Molecular basis of disease, 2024-03, Vol.1870 (3), p.167025-167025, Article 167025

2024

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miR-146b-5p regulates bone marrow mesenchymal stem cell differentiation by SIAH2/PPARγ in aplastic anemia children and benzene-induced aplastic anemia mouse model

Cell cycle (Georgetown, Tex.), 2020-10, Vol.19 (19), p.2460-2471

2020

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Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression

Haematologica (Roma), 2018-09, Vol.103 (9), p.1451

2018

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Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia

Haematologica (Roma), 2015-12, Vol.100 (12), p.1546

2015

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Rapamycin is highly effective in murine models of immune-mediated bone marrow failure

Haematologica (Roma), 2017-10, Vol.102 (10), p.1691

2017

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IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation

Blood, 2014-12, Vol.124 (25), p.3699-3708

2014

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Germline GATA2 Mutation and Bone Marrow Failure

Hematology/oncology clinics of North America, 2018-08, Vol.32 (4), p.713

2018

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Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans

PloS one, 2014-11, Vol.9 (11), p.e113747-e113747

2014

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Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

Blood, 2015-01, Vol.125 (4), p.706-709

2015

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Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models

Science translational medicine, 2023-01, Vol.15 (678), p.eabo0205

2023

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Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia

Haematologica (Roma), 2022-12, Vol.107 (12), p.2834

2022

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Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia

Leukemia, 2022-03, Vol.36 (3), p.834-846

2022

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Donor telomere length and causes of death after unrelated hematopoietic cell transplantation in patients with marrow failure

Blood, 2018-05, Vol.131 (21), p.2393-2398

2018

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Evaluation and Management of Hematopoietic Failure in Dyskeratosis Congenita

Hematology/oncology clinics of North America, 2018-08, Vol.32 (4), p.669

Agarwal, Suneet

2018

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Characterization of bone marrow mesenchymal stromal cells in aplastic anaemia

British journal of haematology, 2015-06, Vol.169 (6), p.804-813

2015

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Aplastic anemia, cellular and molecular aspects

Cell biology international, 2021-12, Vol.45 (12), p.2395-2402

2021

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Eltrombopag mobilizes iron in patients with aplastic anemia

Blood, 2018-05, Vol.131 (21), p.2399-2402

2018

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Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia

European journal of cell biology, 2018-01, Vol.97 (1), p.32-43

2018

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Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts

GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia

Telomerase gene therapy rescues telomere length, bone marrow aplasia, and survival in mice with aplastic anemia

Iron toxicity – Its effect on the bone marrow

The complex pathophysiology of acquired aplastic anaemia

Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia

Hematopoietic stem progenitor cells lacking HLA differ from those lacking GPI-anchored proteins in the hierarchical stage and sensitivity to immune attack in patients with acquired aplastic anemia

Elevated senescence in the bone marrow mesenchymal stem cells of acquired aplastic anemia patients: A possible implication of DNA damage responses and telomere attrition

miR-146b-5p regulates bone marrow mesenchymal stem cell differentiation by SIAH2/PPARγ in aplastic anemia children and benzene-induced aplastic anemia mouse model

Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression

Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia

Rapamycin is highly effective in murine models of immune-mediated bone marrow failure

IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation

Germline GATA2 Mutation and Bone Marrow Failure

Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans

Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia

Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia

Donor telomere length and causes of death after unrelated hematopoietic cell transplantation in patients with marrow failure

Evaluation and Management of Hematopoietic Failure in Dyskeratosis Congenita

Characterization of bone marrow mesenchymal stromal cells in aplastic anaemia

Aplastic anemia, cellular and molecular aspects

Eltrombopag mobilizes iron in patients with aplastic anemia

Epigenetic and microenvironmental alterations in bone marrow associated with ROS in experimental aplastic anemia

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