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Intracellular tau fragment droplets serve as seeds for tau fibrils

Structure (London), 2024-10, Vol.32 (10), p.1793-1807.e6

2024

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The degradation of α--synuclein is limited by dynein to drive the AALP pathway through HDAC6 upon paraquat exposure

Ecotoxicology and environmental safety, 2024-09, Vol.283, p.116841, Article 116841

2024

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The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregation

Human genetics, 2024-08, Vol.143 (8), p.965-978

2024

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Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells

Scientific reports, 2024-06, Vol.14 (1), p.14552-14, Article 14552

2024

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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

The Journal of cell biology, 2024-06, Vol.223 (6)

2024

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ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC

Cancer letters, 2024-06, Vol.591, p.216895, Article 216895

2024

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LC3A-mediated autophagy elicits PERK-eIF2α-ATF4 axis activation and mitochondrial dysfunction: Exposing vulnerability in aggresome-positive cancer cells

The Journal of biological chemistry, 2024-06, Vol.300 (6), p.107398, Article 107398

2024

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Widespread nuclear lamina injuries defeat proteostatic purposes of α-synuclein amyloid inclusions

Journal of cell science, 2024-04, Vol.137 (7)

2024

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Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment

Scientific reports, 2024-02, Vol.14 (1), p.3768-3768, Article 3768

2024

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Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer

Nature communications, 2024-02, Vol.15 (1), p.1321-1321, Article 1321

2024

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CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly

PLoS genetics, 2024-02, Vol.20 (2), p.e1011138

2024

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The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis

The FEBS journal, 2023-12, Vol.290 (23), p.5581-5604

2023

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Conversion of methylmercury into inorganic mercury via organomercurial lyase (MerB) activates autophagy and aggresome formation

Scientific reports, 2023-11, Vol.13 (1), p.19958-19958, Article 19958

2023

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Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction

Cellular & molecular biology letters, 2023-10, Vol.28 (1), p.85-85, Article 85

2023

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Diallyl Trisulfide Causes Male Infertility with Oligoasthenoteratospermia in Sitotroga cerealella through the Ubiquitin–Proteasome Pathway

Cells (Basel, Switzerland), 2023-10, Vol.12 (20), p.2507

2023

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The development of new biomarkers of spermatozoa quality in cattle

Frontiers in veterinary science, 2023-10, Vol.10, p.1258295-1258295

2023

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YTHDF2 facilitates aggresome formation via UPF1 in an m6A-independent manner

Nature communications, 2023-10, Vol.14 (1), p.6248-6248, Article 6248

2023

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Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2

EMBO molecular medicine, 2023-09, Vol.15 (9), p.e17451-e17451

2023

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Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers

Nature communications, 2023-07, Vol.14 (1), p.4450-17, Article 4450

2023

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The chaperone-assisted selective autophagy complex dynamics and dysfunctions

Autophagy, 2023-06, Vol.19 (6), p.1619-1641

2023

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Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104710-104710, Article 104710

2023

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β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells

International journal of molecular sciences, 2023-06, Vol.24 (12), p.9867

2023

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Formation of aggresomes with hydrogel-like characteristics by proteasome inhibition

Biochimica et biophysica acta. Gene regulatory mechanisms, 2023-06, Vol.1866 (2), p.194932-194932, Article 194932

2023

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Characterization of Skeletal Muscle Biopsy and Derived Myoblasts in a Patient Carrying Arg14del Mutation in Phospholamban Gene

Cells (Basel, Switzerland), 2023-05, Vol.12 (10), p.1405

2023

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Physapruin A Exerts Endoplasmic Reticulum Stress to Trigger Breast Cancer Cell Apoptosis via Oxidative Stress

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8853

2023

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Intracellular tau fragment droplets serve as seeds for tau fibrils

The degradation of α--synuclein is limited by dynein to drive the AALP pathway through HDAC6 upon paraquat exposure

The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregation

Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC

LC3A-mediated autophagy elicits PERK-eIF2α-ATF4 axis activation and mitochondrial dysfunction: Exposing vulnerability in aggresome-positive cancer cells

Widespread nuclear lamina injuries defeat proteostatic purposes of α-synuclein amyloid inclusions

Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment

Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer

CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly

The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis

Conversion of methylmercury into inorganic mercury via organomercurial lyase (MerB) activates autophagy and aggresome formation

Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction

Diallyl Trisulfide Causes Male Infertility with Oligoasthenoteratospermia in Sitotroga cerealella through the Ubiquitin–Proteasome Pathway

The development of new biomarkers of spermatozoa quality in cattle

YTHDF2 facilitates aggresome formation via UPF1 in an m6A-independent manner

Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2

Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers

The chaperone-assisted selective autophagy complex dynamics and dysfunctions

Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells

Formation of aggresomes with hydrogel-like characteristics by proteasome inhibition

Characterization of Skeletal Muscle Biopsy and Derived Myoblasts in a Patient Carrying Arg14del Mutation in Phospholamban Gene

Physapruin A Exerts Endoplasmic Reticulum Stress to Trigger Breast Cancer Cell Apoptosis via Oxidative Stress

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