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Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β-mediated colitis

The Journal of clinical investigation, 2020-04, Vol.130 (4), p.1793-1807

2020

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Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients

Journal of clinical immunology, 2021-10, Vol.41 (7), p.1633-1647

2021

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A Monogenic Disease with a Variety of Phenotypes: Deficiency of Adenosine Deaminase 2

Journal of rheumatology, 2020-01, Vol.47 (1), p.117-125

2020

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Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K

The Journal of experimental medicine, 2012-03, Vol.209 (3), p.463-470

2012

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Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency

The Journal of clinical investigation, 2017-05, Vol.127 (5), p.1689-1699

2017

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Bruton's Tyrosine Kinase: From X-Linked Agammaglobulinemia Toward Targeted Therapy for B-Cell Malignancies

Journal of clinical oncology, 2014-06, Vol.32 (17), p.1830-1839

2014

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Dysregulation in B‐cell responses and T follicular helper cell function in ADA2 deficiency patients

European journal of immunology, 2021-01, Vol.51 (1), p.206-219

2021

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Bruton's tyrosine kinase—an integral protein of B cell development that also has an essential role in the innate immune system

Journal of leukocyte biology, 2014-02, Vol.95 (2), p.243-250

2014

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Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects

Journal of allergy and clinical immunology, 2013-02, Vol.131 (2), p.477-485.e1

2013

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Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies

Current opinion in allergy and clinical immunology, 2013-12, Vol.13 (6), p.630-638

2013

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Impact of amino acid substitution in the kinase domain of Bruton tyrosine kinase and its association with X-linked agammaglobulinemia

International journal of biological macromolecules, 2020-12, Vol.164, p.2399-2408

2020

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BTK Signaling in B Cell Differentiation and Autoimmunity

B Cell Receptor Signaling, 2016, Vol.393, p.67-105

2016

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Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity

Blood, 2015-03, Vol.125 (10), p.1643-1652

2015

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Inhibitors of BTK and ITK: State of the New Drugs for Cancer, Autoimmunity and Inflammatory Diseases

Scandinavian journal of immunology, 2013-08, Vol.78 (2), p.130-139

2013

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Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.4067-4081

2014

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A novel Bruton tyrosine kinase gene variation was found in an adult with X‐linked agammaglobulinemia during blood cross‐matching prior to surgical operation

Transfusion medicine (Oxford, England), 2019-10, Vol.29 (5), p.364-368

2019

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Bruton's tyrosine kinase is required for TLR-dependent heme oxygenase-1 gene activation via Nrf2 in macrophages

The Journal of immunology (1950), 2011-07, Vol.187 (2), p.817-827

2011

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TEC family kinases in health and disease – loss‐of‐function of BTK and ITK and the gain‐of‐function fusions ITK–SYK and BTK–SYK

The FEBS journal, 2011-06, Vol.278 (12), p.2001-2010

2011

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Elevated cytokine production restores bone resorption by human Btk‐deficient osteoclasts

Journal of bone and mineral research, 2011-01, Vol.26 (1), p.182-192

2011

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Effects of enzyme replacement therapy on immune function in ADA deficiency patient

Clinical immunology (Orlando, Fla.), 2015-12, Vol.161 (2), p.391-393

2015

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A new mutation that predicted a drastic alteration of the BTK protein function

Gene, 2013-09, Vol.527 (1), p.426-428

2013

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The Effects of Bruton Tyrosine Kinase Inhibition on Chemotaxis and Superoxide Generation in Human Neutrophils

Journal of clinical immunology, 2014-07, Vol.34 (5), p.555-560

2014

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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. 1993

The Journal of immunology (1950), 2012-04, Vol.188 (7), p.2936-2947

2012

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The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993

The Journal of immunology (1950), 2012-04, Vol.188 (7), p.2948-2955

2012

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Consequences of two naturally occurring missense mutations in the structure and function of Bruton agammaglobulinemia tyrosine kinase

IUBMB life, 2012-04, Vol.64 (4), p.346-353

2012

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Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β-mediated colitis

Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients

A Monogenic Disease with a Variety of Phenotypes: Deficiency of Adenosine Deaminase 2

Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency

Bruton's Tyrosine Kinase: From X-Linked Agammaglobulinemia Toward Targeted Therapy for B-Cell Malignancies

Dysregulation in B‐cell responses and T follicular helper cell function in ADA2 deficiency patients

Bruton's tyrosine kinase—an integral protein of B cell development that also has an essential role in the innate immune system

Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects

Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies

Impact of amino acid substitution in the kinase domain of Bruton tyrosine kinase and its association with X-linked agammaglobulinemia

BTK Signaling in B Cell Differentiation and Autoimmunity

Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity

Inhibitors of BTK and ITK: State of the New Drugs for Cancer, Autoimmunity and Inflammatory Diseases

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

A novel Bruton tyrosine kinase gene variation was found in an adult with X‐linked agammaglobulinemia during blood cross‐matching prior to surgical operation

Bruton's tyrosine kinase is required for TLR-dependent heme oxygenase-1 gene activation via Nrf2 in macrophages

TEC family kinases in health and disease – loss‐of‐function of BTK and ITK and the gain‐of‐function fusions ITK–SYK and BTK–SYK

Elevated cytokine production restores bone resorption by human Btk‐deficient osteoclasts

Effects of enzyme replacement therapy on immune function in ADA deficiency patient

A new mutation that predicted a drastic alteration of the BTK protein function

The Effects of Bruton Tyrosine Kinase Inhibition on Chemotaxis and Superoxide Generation in Human Neutrophils

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. 1993

The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993

Consequences of two naturally occurring missense mutations in the structure and function of Bruton agammaglobulinemia tyrosine kinase

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