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Functional Diversity and Engineering of the Adenylation Domains in Nonribosomal Peptide Synthetases

Marine drugs, 2024-07, Vol.22 (8), p.349

2024

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Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models. e62136

PloS one, 2013-04, Vol.8 (4)

2013

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Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Journal of industrial microbiology & biotechnology, 2019-03, Vol.46 (3-4), p.515-536

2019

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De novo design and engineering of non-ribosomal peptide synthetases

Nature chemistry, 2018-03, Vol.10 (3), p.275-281

2018

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Adenylation Domains in Nonribosomal Peptide Engineering

Chembiochem : a European journal of chemical biology, 2019-06, Vol.20 (11), p.1347-1356

2019

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Replacing Commercial 6‐Phosphofructokinase in an Online Pyrophosphate Detection Assay

Chembiochem : a European journal of chemical biology, 2022-09, Vol.23 (18), p.e202200325-n/a

2022

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Regulation of microRNA biogenesis

Nature reviews. Molecular cell biology, 2014-08, Vol.15 (8), p.509-524

2014

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Engineered Biosynthesis through the Adenylation Domains from Nonribosomal Peptide Synthetases

Current topics in medicinal chemistry, 2023-01, Vol.23 (20), p.1973-1984

2023

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Advances in the adenylation domain: discovery of diverse non-ribosomal peptides

Applied microbiology and biotechnology, 2023-07, Vol.107 (13), p.4187-4197

2023

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Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

Nature cell biology, 2022-06, Vol.24 (6), p.968-980

2022

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Characterization and Structural Determination of CmnG‐A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis

Chembiochem : a European journal of chemical biology, 2022-12, Vol.23 (24), p.e202200563-n/a

2022

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Role of Two Exceptional trans Adenylation Domains and MbtH‐like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382

Chembiochem : a European journal of chemical biology, 2020-09, Vol.21 (18), p.2659-2666

2020

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Selective poly adenylation predicts the efficacy of immunotherapy in patients with lung adenocarcinoma by multiple omics research

Anti-cancer drugs, 2022-10

2022

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A eukaryotic-like ubiquitination system in bacterial antiviral defence

Nature (London), 2024-07, Vol.631 (8022), p.843-849

2024

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Hydroxy Acid Activation in Fungal Non‐Ribosomal Peptide Synthesis Assessed by Site‐Directed Mutagenesis

Chembiochem : a European journal of chemical biology, 2023-07, Vol.24 (13), p.e202300233-n/a

2023

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One-pot synthesis of 2,5-diketopiperazine with high titer and versatility using adenylation enzyme

Applied microbiology and biotechnology, 2022-06, Vol.106 (12), p.4469-4479

2022

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An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket

Angewandte Chemie International Edition, 2019-05, Vol.58 (21), p.6906-6910

International ed. in English, 2019

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Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD

Journal of biological inorganic chemistry, 2022, Vol.27 (6), p.541-551

2022

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Streamlining differential exon and 3' UTR usage with diffUTR

BMC bioinformatics, 2021-04, Vol.22 (1), p.189-189, Article 189

2021

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Cover Feature: An Unusual Fatty Acyl:Adenylate Ligase (FAAL)–Acyl Carrier Protein (ACP) Didomain in Ambruticin Biosynthesis (ChemBioChem 10/2018)

Chembiochem : a European journal of chemical biology, 2018-05, Vol.19 (10), p.1000-1000

2018

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PARN and TOE1 Constitute a 3′ End Maturation Module for Nuclear Non-coding RNAs

Cell reports (Cambridge), 2018-04, Vol.23 (3), p.888-898

2018

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Structural basis for UFM1 transfer from UBA5 to UFC1

Nature communications, 2021-09, Vol.12 (1), p.5708-5708, Article 5708

2021

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Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina

Applied and environmental microbiology, 2021-01, Vol.87 (3), p.1

2021

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Efficient rational modification of non-ribosomal peptides by adenylation domain substitution

Nature communications, 2020-09, Vol.11 (1), p.4554-4554, Article 4554

2020

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Discovery and resistance mechanism of a selective CDK12 degrader

Nature chemical biology, 2021-06, Vol.17 (6), p.675-683

2021

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Functional Diversity and Engineering of the Adenylation Domains in Nonribosomal Peptide Synthetases

Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models. e62136

Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

De novo design and engineering of non-ribosomal peptide synthetases

Adenylation Domains in Nonribosomal Peptide Engineering

Replacing Commercial 6‐Phosphofructokinase in an Online Pyrophosphate Detection Assay

Regulation of microRNA biogenesis

Engineered Biosynthesis through the Adenylation Domains from Nonribosomal Peptide Synthetases

Advances in the adenylation domain: discovery of diverse non-ribosomal peptides

Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

Characterization and Structural Determination of CmnG‐A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis

Role of Two Exceptional trans Adenylation Domains and MbtH‐like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382

Selective poly adenylation predicts the efficacy of immunotherapy in patients with lung adenocarcinoma by multiple omics research

A eukaryotic-like ubiquitination system in bacterial antiviral defence

Hydroxy Acid Activation in Fungal Non‐Ribosomal Peptide Synthesis Assessed by Site‐Directed Mutagenesis

One-pot synthesis of 2,5-diketopiperazine with high titer and versatility using adenylation enzyme

An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket

Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD

Streamlining differential exon and 3' UTR usage with diffUTR

Cover Feature: An Unusual Fatty Acyl:Adenylate Ligase (FAAL)–Acyl Carrier Protein (ACP) Didomain in Ambruticin Biosynthesis (ChemBioChem 10/2018)

PARN and TOE1 Constitute a 3′ End Maturation Module for Nuclear Non-coding RNAs

Structural basis for UFM1 transfer from UBA5 to UFC1

Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina

Efficient rational modification of non-ribosomal peptides by adenylation domain substitution

Discovery and resistance mechanism of a selective CDK12 degrader

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