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Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering

Molecular bioSystems, 2015-01, Vol.11 (1), p.38-59

2015

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Molecular basis for interactions between an acyl carrier protein and a ketosynthase

Nature chemical biology, 2019-07, Vol.15 (7), p.669-671

2019

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The structural biology of type II fatty acid biosynthesis

Annual review of biochemistry, 2005-01, Vol.74 (1), p.791-831

2005

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Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803

FEBS letters, 2015-10, Vol.589 (20), p.3052-3057

2015

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The Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Synthase III Activity Is Inhibited by Phosphorylation on a Single Threonine Residue

The Journal of biological chemistry, 2009-03, Vol.284 (10), p.6414-6424

2009

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Iron–sulfur cluster biogenesis and trafficking in mitochondria

The Journal of biological chemistry, 2017-08, Vol.292 (31), p.12754-12763

2017

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Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

Nature communications, 2017-11, Vol.8 (1), p.1287-15, Article 1287

2017

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Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli

The Journal of biological chemistry, 2006-12, Vol.281 (51), p.39285-39293

2006

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Diversity in enoyl-acyl carrier protein reductases

Cellular and molecular life sciences : CMLS, 2009-05, Vol.66 (9), p.1507-1517

2009

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Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP Synthase by Isoniazid

Science (American Association for the Advancement of Science), 1998-06, Vol.280 (5369), p.1607-1610

1998

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The Protonation State of Catalytic Residues in the Resting State of KasA Revisited: Detailed Mechanism for the Activation of KasA by Its Own Substrate

Biochemistry (Easton), 2014-02, Vol.53 (5), p.919-931

2014

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Structural basis for selectivity in a highly reducing type II polyketide synthase

Nature chemical biology, 2020-07, Vol.16 (7), p.776-782

2020

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ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly

Molecular cell, 2018-08, Vol.71 (4), p.567-580.e4

2018

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The Initiating Steps of a Type II Fatty Acid Synthase in Plasmodium falciparum are Catalyzed by pfacp, pfmcat, and pfKASIII

Biochemistry (Easton), 2003-02, Vol.42 (4), p.1160-1169

2003

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Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases

The FEBS journal, 2006-02, Vol.273 (4), p.695-710

2006

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Mammalian iron–sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins

Current opinion in chemical biology, 2020-04, Vol.55, p.34-44

2020

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Structure and mechanism of assembly line polyketide synthases

Current opinion in structural biology, 2016-12, Vol.41, p.10-18

2016

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Structural rearrangements of a polyketide synthase module during its catalytic cycle

Nature (London), 2014-06, Vol.510 (7506), p.560-564

2014

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Current understanding of fatty acid biosynthesis and the acyl carrier protein

Biochemical journal, 2010-08, Vol.430 (1), p.1-19

2010

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Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1802-1807

2016

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Biosynthesis of 4-Acyl-5-aminoimidazole Alkaloids Featuring a New Friedel-Crafts Acyltransferase

Journal of the American Chemical Society, 2023-12, Vol.145 (48), p.26308-26317

2023

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Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity

The Journal of biological chemistry, 2005-09, Vol.280 (37), p.32539

2005

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Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

Nature (London), 2014-01, Vol.505 (7483), p.427-431

2014

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High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS)

Organic letters, 2014-02, Vol.16 (3), p.940-943

2014

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Structural study of acyl carrier protein of Enterococcus faecalis and its interaction with enzymes in de novo fatty acid synthesis

Biochemical and biophysical research communications, 2022-12, Vol.637, p.232-239

2022

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Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering

Molecular basis for interactions between an acyl carrier protein and a ketosynthase

The structural biology of type II fatty acid biosynthesis

Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803

The Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Synthase III Activity Is Inhibited by Phosphorylation on a Single Threonine Residue

Iron–sulfur cluster biogenesis and trafficking in mitochondria

Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli

Diversity in enoyl-acyl carrier protein reductases

Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP Synthase by Isoniazid

The Protonation State of Catalytic Residues in the Resting State of KasA Revisited: Detailed Mechanism for the Activation of KasA by Its Own Substrate

Structural basis for selectivity in a highly reducing type II polyketide synthase

ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly

The Initiating Steps of a Type II Fatty Acid Synthase in Plasmodium falciparum are Catalyzed by pfacp, pfmcat, and pfKASIII

Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases

Mammalian iron–sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins

Structure and mechanism of assembly line polyketide synthases

Structural rearrangements of a polyketide synthase module during its catalytic cycle

Current understanding of fatty acid biosynthesis and the acyl carrier protein

Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Biosynthesis of 4-Acyl-5-aminoimidazole Alkaloids Featuring a New Friedel-Crafts Acyltransferase

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS)

Structural study of acyl carrier protein of Enterococcus faecalis and its interaction with enzymes in de novo fatty acid synthesis

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