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Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development

Physiological reviews, 2018-04, Vol.98 (2), p.919-1053

2018

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Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large‐scale and targeted quantitative proteomics

Proteomics (Weinheim), 2017-04, Vol.17 (7), p.np-n/a

2017

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Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2018-09, Vol.320 (9), p.880

2018

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Evaluation of Toxicant and Carcinogen Metabolites in the Urine of E-Cigarette Users Versus Cigarette Smokers

Nicotine & tobacco research, 2015-06, Vol.17 (6), p.704-709

2015

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Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die

Cell death and differentiation, 2017-02, Vol.24 (2), p.317-329

2017

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Oxidized lipids block antigen cross-presentation by dendritic cells in cancer

The Journal of immunology (1950), 2014-03, Vol.192 (6), p.2920-2931

2014

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Effects of Switching to Electronic Cigarettes with and without Concurrent Smoking on Exposure to Nicotine, Carbon Monoxide, and Acrolein

Cancer prevention research (Philadelphia, Pa.), 2015-09, Vol.8 (9), p.873-878

2015

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Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Neurobiology of disease, 2015-12, Vol.84, p.109-119

2015

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TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

The Journal of experimental medicine, 2020-02, Vol.217 (2)

2020

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‘Real‐world’ compensatory behaviour with low nicotine concentration e‐liquid: subjective effects and nicotine, acrolein and formaldehyde exposure

Addiction (Abingdon, England), 2018-10, Vol.113 (10), p.1874-1882

2018

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Urinary Biomarkers of Prenatal Atrazine Exposure and Adverse Birth Outcomes in the PELAGIE Birth Cohort

Environmental health perspectives, 2011-07, Vol.119 (7), p.1034-1041

2011

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Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms

The Journal of neuroscience, 2014-01, Vol.34 (5), p.1672-1688

2014

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S-nitrosothiols as nitrite alternatives: Effects on residual nitrite, lipid oxidation, volatile profile, and cured color of restructured cooked ham

Meat science, 2024-03, Vol.209, p.109397-109397, Article 109397

2024

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The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability

The Journal of biological chemistry, 2018-01, Vol.293 (2), p.717-730

2018

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MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation

PloS one, 2015-02, Vol.10 (2), p.e0115855-e0115855

2015

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Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window"

Scientific reports, 2015-03, Vol.5 (1), p.9344, Article 9344

2015

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Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche

Cell reports (Cambridge), 2015-10, Vol.13 (2), p.302-314

2015

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Neuroprotective effects of N-acetylcysteine amide against oxidative injury in an aging model of organotypic hippocampal slice cultures

Neuroreport, 2022-03, Vol.33 (4), p.173

2022

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Protein kinase A inhibitor proteins (PKIs) divert GPCR‐Gαs‐cAMP signaling toward EPAC and ERK activation and are involved in tumor growth

The FASEB journal, 2020-10, Vol.34 (10), p.13900-13917

2020

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Specific CpG sites methylation is associated with hematotoxicity in low-dose benzene-exposed workers

Environment international, 2024-04, Vol.186, p.108645-108645, Article 108645

2024

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Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia

Pain (Amsterdam), 2018-11, Vol.159 (11), p.2383-2393

2018

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L-NAC and L-NAC methyl ester prevent and overcome physical dependence to fentanyl in male rats

Scientific reports, 2024-04, Vol.14 (1), p.9091-16, Article 9091

2024

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Long-term decomposition of aqueous S-nitrosoglutathione and S-nitroso-N-acetylcysteine: Influence of concentration, temperature, pH and light

Nitric oxide, 2019-03, Vol.84, p.30-37

2019

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Urinary biomonitoring of subjects with different smoking habits. Part II: an untargeted metabolomic approach and the comparison with the targeted measurement of mercapturic acids

Toxicology letters, 2020-09, Vol.329, p.56-66

2020

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S‑Nitroso‑N‑acetyl‑l‑cysteine Ethyl Ester (SNACET) Catheter Lock Solution to Reduce Catheter-Associated Infections

ACS applied materials & interfaces, 2021-06, Vol.13 (22), p.25813-25824

2021

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Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development

Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large‐scale and targeted quantitative proteomics

Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial

Evaluation of Toxicant and Carcinogen Metabolites in the Urine of E-Cigarette Users Versus Cigarette Smokers

Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die

Oxidized lipids block antigen cross-presentation by dendritic cells in cancer

Effects of Switching to Electronic Cigarettes with and without Concurrent Smoking on Exposure to Nicotine, Carbon Monoxide, and Acrolein

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

‘Real‐world’ compensatory behaviour with low nicotine concentration e‐liquid: subjective effects and nicotine, acrolein and formaldehyde exposure

Urinary Biomarkers of Prenatal Atrazine Exposure and Adverse Birth Outcomes in the PELAGIE Birth Cohort

Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms

S-nitrosothiols as nitrite alternatives: Effects on residual nitrite, lipid oxidation, volatile profile, and cured color of restructured cooked ham

The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability

MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation

Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window"

Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche

Neuroprotective effects of N-acetylcysteine amide against oxidative injury in an aging model of organotypic hippocampal slice cultures

Protein kinase A inhibitor proteins (PKIs) divert GPCR‐Gαs‐cAMP signaling toward EPAC and ERK activation and are involved in tumor growth

Specific CpG sites methylation is associated with hematotoxicity in low-dose benzene-exposed workers

Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia

L-NAC and L-NAC methyl ester prevent and overcome physical dependence to fentanyl in male rats

Long-term decomposition of aqueous S-nitrosoglutathione and S-nitroso-N-acetylcysteine: Influence of concentration, temperature, pH and light

Urinary biomonitoring of subjects with different smoking habits. Part II: an untargeted metabolomic approach and the comparison with the targeted measurement of mercapturic acids

S‑Nitroso‑N‑acetyl‑l‑cysteine Ethyl Ester (SNACET) Catheter Lock Solution to Reduce Catheter-Associated Infections

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