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Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (6), p.E1166-E1173

2018

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Acetate Dependence of Tumors

Cell, 2014-12, Vol.159 (7), p.1591-1602

2014

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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Nature (London), 2020-03, Vol.579 (7800), p.586-591

2020

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Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory

Nature (London), 2017-06, Vol.546 (7658), p.381-386

2017

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Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Cell, 2014-12, Vol.159 (7), p.1603-1614

2014

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Structure, Function, and Mechanism of the Nickel Metalloenzymes, CO Dehydrogenase, and Acetyl-CoA Synthase

Chemical reviews, 2014-04, Vol.114 (8), p.4149-4174

2014

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Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

Molecular cell, 2015-04, Vol.58 (2), p.203-215

2015

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Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

Cell reports (Cambridge), 2017-01, Vol.18 (3), p.647-658

2017

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Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

Cell metabolism, 2021-01, Vol.33 (1), p.78-93.e7

2021

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Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy

Molecular cell, 2017-06, Vol.66 (5), p.684-697.e9

2017

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Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (5), p.1252-1264

2021

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ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.E9499-E9506

2018

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Mixed Valence {Ni2+Ni1+} Clusters as Models of Acetyl Coenzyme A Synthase Intermediates

Journal of the American Chemical Society, 2024-07, Vol.146 (30), p.21034-21043

2024

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Capturing a methanogenic carbon monoxide dehydrogenase/acetyl-CoA synthase complex via cryogenic electron microscopy

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (41), p.e2410995121

2024

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ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5930), p.1076-1080

2009

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Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia

Nature communications, 2016-06, Vol.7 (1), p.11960-11960, Article 11960

2016

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Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer

Gastroenterology (New York, N.Y. 1943), 2022-11, Vol.163 (5), p.1281-1293.e1

2022

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Reversible Lysine Acetylation Controls the Activity of the Mitochondrial Enzyme Acetyl-CoA Synthetase 2

Proceedings of the National Academy of Sciences - PNAS, 2006-07, Vol.103 (27), p.10224-10229

2006

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ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses

The Journal of experimental medicine, 2024-09, Vol.221 (9)

2024

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Molecular mechanics studies of factors affecting overall rate in cascade reactions: Multi‐enzyme colocalization and environment

Protein science, 2024-10, Vol.33 (10), p.e5175-n/a

2024

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Acetyl-CoA synthetase activity is enzymatically regulated by lysine acetylation using acetyl-CoA or acetyl-phosphate as donor molecule

Nature communications, 2024-07, Vol.15 (1), p.6002-22, Article 6002

2024

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Coupling CO 2 Reduction and Acetyl-CoA Formation: The Role of a CO Capturing Tunnel in Enzymatic Catalysis

Angewandte Chemie International Edition, 2024-07, Vol.63 (31), p.e202405120

2024

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ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

Cell reports (Cambridge), 2016-10, Vol.17 (4), p.1037-1052

2016

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Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes

Acetate Dependence of Tumors

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

Structure, Function, and Mechanism of the Nickel Metalloenzymes, CO Dehydrogenase, and Acetyl-CoA Synthase

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism

Mixed Valence {Ni2+Ni1+} Clusters as Models of Acetyl Coenzyme A Synthase Intermediates

Capturing a methanogenic carbon monoxide dehydrogenase/acetyl-CoA synthase complex via cryogenic electron microscopy

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia

Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer

Reversible Lysine Acetylation Controls the Activity of the Mitochondrial Enzyme Acetyl-CoA Synthetase 2

ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses

Molecular mechanics studies of factors affecting overall rate in cascade reactions: Multi‐enzyme colocalization and environment

Acetyl-CoA synthetase activity is enzymatically regulated by lysine acetylation using acetyl-CoA or acetyl-phosphate as donor molecule

Coupling CO 2 Reduction and Acetyl-CoA Formation: The Role of a CO Capturing Tunnel in Enzymatic Catalysis

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

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