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Detergent-free purification of ABC (ATP-binding-cassette) transporters

Biochemical journal, 2014-07, Vol.461 (2), p.269-278

2014

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Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators

Molecules (Basel, Switzerland), 2020-07, Vol.25 (15), p.3364

2020

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ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1

Cell, 2018-01, Vol.172 (1-2), p.81-89.e10

2018

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Structural and functional aspects of P-glycoprotein and its inhibitors

Life sciences (1973), 2018-12, Vol.214, p.118-123

2018

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Three decades of P-gp inhibitors: skimming through several generations and scaffolds

Current medicinal chemistry, 2012-05, Vol.19 (13), p.1946-2025

2012

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Comparison of mechanistic transport cycle models of ABC exporters

Biochimica et biophysica acta. Biomembranes, 2018-04, Vol.1860 (4), p.818-832

2018

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pH/Redox Dual-Responsive Polyplex with Effective Endosomal Escape for Codelivery of siRNA and Doxorubicin against Drug-Resistant Cancer Cells

ACS applied materials & interfaces, 2019-05, Vol.11 (18), p.16296-16310

2019

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Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

Phytomedicine (Stuttgart), 2019-09, Vol.62, p.152945-152945, Article 152945

2019

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Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

Nature (London), 2012-10, Vol.490 (7421), p.566-569

2012

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Auxin-transporting ABC transporters are defined by a conserved D/E-P motif regulated by a prolylisomerase

The Journal of biological chemistry, 2020-09, Vol.295 (37), p.13094-13105

2020

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A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein

Molecular pharmacology, 2019-11, Vol.96 (5), p.629-640

2019

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Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer

Molecular bioSystems, 2016-07, Vol.12 (8), p.2458-247

2016

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Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1304-1316

2017

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A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation

Proceedings of the National Academy of Sciences - PNAS, 2023-03, Vol.120 (11), p.e2220012120-e2220012120

2023

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Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9704-9709

2013

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Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models

Cancer letters, 2013-01, Vol.328 (2), p.307-317

2013

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Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

Trends in biochemical sciences (Amsterdam. Regular ed.), 2010-01, Vol.35 (1), p.36-42

2010

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Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer

Scientific reports, 2017-08, Vol.7 (1), p.7972-18, Article 7972

2017

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Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition

Xenobiotica, 2008-08, Vol.38 (7-8), p.802-832

Zhou, S.-F.

2008

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Reduced P-glycoprotein recognition of a radioiodine-labeled phosphonium cation by stilbenylation for mitochondrial membrane potential based-imaging

Bioorganic & medicinal chemistry, 2023-04, Vol.84, p.117260-117260, Article 117260

2023

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In vivo FRET analyses reveal a role of ATP hydrolysis–associated conformational changes in human P-glycoprotein

The Journal of biological chemistry, 2020-04, Vol.295 (15), p.5002-5011

2020

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Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies

International journal of molecular sciences, 2020-06, Vol.21 (11), p.4058

2020

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Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein

The FASEB journal, 2007-12, Vol.21 (14), p.3937-3948

2007

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A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1740-1751

2011

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Synthesis and biological evaluation of thiophenylbenzofuran derivatives as potential P-glycoprotein inhibitors

European journal of medicinal chemistry, 2020-09, Vol.201, p.112422-112422, Article 112422

2020

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Detergent-free purification of ABC (ATP-binding-cassette) transporters

Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators

ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1

Structural and functional aspects of P-glycoprotein and its inhibitors

Three decades of P-gp inhibitors: skimming through several generations and scaffolds

Comparison of mechanistic transport cycle models of ABC exporters

pH/Redox Dual-Responsive Polyplex with Effective Endosomal Escape for Codelivery of siRNA and Doxorubicin against Drug-Resistant Cancer Cells

Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

Auxin-transporting ABC transporters are defined by a conserved D/E-P motif regulated by a prolylisomerase

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein

Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer

Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior

A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation

Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer

Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition

Reduced P-glycoprotein recognition of a radioiodine-labeled phosphonium cation by stilbenylation for mitochondrial membrane potential based-imaging

In vivo FRET analyses reveal a role of ATP hydrolysis–associated conformational changes in human P-glycoprotein

Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies

Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein

A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

Synthesis and biological evaluation of thiophenylbenzofuran derivatives as potential P-glycoprotein inhibitors

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