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Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

Arteriosclerosis, thrombosis, and vascular biology, 2018-07, Vol.38 (7), p.1537

2018

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MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1

Matrix biology, 2016-12, Vol.56, p.57-73

2016

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Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

Circulation (New York, N.Y.), 2018-01, Vol.137 (2), p.166-183

2018

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The Anti-ADAMTS-5 Nanobody ® M6495 Protects Cartilage Degradation Ex Vivo

International journal of molecular sciences, 2020-08, Vol.21 (17), p.5992

2020

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Effect of inhibiting MMP13 and ADAMTS5 by intra-articular injection of small interfering RNA in a surgically induced osteoarthritis model of mice

Cell and tissue research, 2017-05, Vol.368 (2), p.379-387

2017

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Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis

Journal of controlled release, 2019-01, Vol.294, p.247-258

2019

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LncRNA MALAT1/MiR-145 Adjusts IL-1β-Induced Chondrocytes Viability and Cartilage Matrix Degradation by Regulating ADAMTS5 in Human Osteoarthritis

Yonsei Medical Journal, 2019, 60(11), , pp.1081-1092

2019

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ADAMTSL5 is an epigenetically activated gene underlying tumorigenesis and drug resistance in hepatocellular carcinoma

Journal of hepatology, 2021-04, Vol.74 (4), p.893-906

2021

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A Highly Selective Hydantoin Inhibitor of Aggrecanase‑1 and Aggrecanase‑2 with a Low Projected Human Dose

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5933-5939

2017

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TMF inhibits extracellular matrix degradation by regulating the C/EBPβ/ADAMTS5 signaling pathway in osteoarthritis

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116501-116501, Article 116501

2024

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MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes

Cellular physiology and biochemistry, 2017, Vol.44 (1), p.38-52

2017

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microRNA -140-5p inhibits colorectal cancer invasion and metastasis by targeting ADAMTS5 and IGFBP5

Stem cell research & therapy, 2016-12, Vol.7 (1), p.180-180

2016

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Mume Fructus reduces interleukin-1 beta-induced cartilage degradation via MAPK downregulation in rat articular chondrocytes

PloS one, 2024-05, Vol.19 (5), p.e0302906-e0302906

2024

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LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway

Bioengineered, 2021-01, Vol.12 (1), p.3148-3158

2021

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Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes

Bioscience reports, 2020-11, Vol.40 (11)

2020

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Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis

Autoimmunity (Chur, Switzerland), 2022-04, Vol.55 (3), p.179-191

2022

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Oleocanthal Inhibits Catabolic and Inflammatory Mediators in LPS-Activated Human Primary Osteoarthritis (OA) Chondrocytes Through MAPKs/NF-κB Pathways

Cellular physiology and biochemistry, 2018-01, Vol.49 (6), p.2414-2426

2018

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Piezo1 mediates the degradation of cartilage extracellular matrix in malocclusion‐induced TMJOA

Oral diseases, 2024-05, Vol.30 (4), p.2425-2438

2024

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The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis

Journal of molecular medicine (Berlin, Germany), 2016-07, Vol.94 (7), p.771-785

2016

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ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity

PLoS biology, 2016-11, Vol.14 (11), p.e1002580-e1002580

2016

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Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

Molecular metabolism (Germany), 2017-07, Vol.6 (7), p.715-724

2017

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ADAMTS‐5: A difficult teenager turning 20

International journal of experimental pathology, 2020-02, Vol.101 (1-2), p.4-20

Santamaria, Salvatore

2020

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The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression

Clinical science (1979), 2017-05, Vol.131 (10), p.965

2017

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Efficiency of dual siRNA-mediated gene therapy for intervertebral disc degeneration (IVDD)

The spine journal, 2019-05, Vol.19 (5), p.896-904

2019

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Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes

Biochemical and biophysical research communications, 2017-09, Vol.491 (2), p.368-373

2017

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Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

The Anti-ADAMTS-5 Nanobody ® M6495 Protects Cartilage Degradation Ex Vivo

Effect of inhibiting MMP13 and ADAMTS5 by intra-articular injection of small interfering RNA in a surgically induced osteoarthritis model of mice

Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis

LncRNA MALAT1/MiR-145 Adjusts IL-1β-Induced Chondrocytes Viability and Cartilage Matrix Degradation by Regulating ADAMTS5 in Human Osteoarthritis

ADAMTSL5 is an epigenetically activated gene underlying tumorigenesis and drug resistance in hepatocellular carcinoma

A Highly Selective Hydantoin Inhibitor of Aggrecanase‑1 and Aggrecanase‑2 with a Low Projected Human Dose

TMF inhibits extracellular matrix degradation by regulating the C/EBPβ/ADAMTS5 signaling pathway in osteoarthritis

MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes

microRNA -140-5p inhibits colorectal cancer invasion and metastasis by targeting ADAMTS5 and IGFBP5

Mume Fructus reduces interleukin-1 beta-induced cartilage degradation via MAPK downregulation in rat articular chondrocytes

LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway

Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes

Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis

Oleocanthal Inhibits Catabolic and Inflammatory Mediators in LPS-Activated Human Primary Osteoarthritis (OA) Chondrocytes Through MAPKs/NF-κB Pathways

Piezo1 mediates the degradation of cartilage extracellular matrix in malocclusion‐induced TMJOA

The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis

ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity

Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

ADAMTS‐5: A difficult teenager turning 20

The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression

Efficiency of dual siRNA-mediated gene therapy for intervertebral disc degeneration (IVDD)

Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes

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