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Regulation of adipose tissue inflammation by interleukin 6

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (6), p.2751-2760

2020

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Platelet-Derived Exosomal MicroRNA-25-3p Inhibits Coronary Vascular Endothelial Cell Inflammation Through Adam10 via the NF-κB Signaling Pathway in ApoE -/- Mice

Frontiers in immunology, 2019-10, Vol.10, p.2205-2205

2019

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ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.666-676

2017

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Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (29), p.14714-14723

2019

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New insights into the tetraspanin Tspan5 using novel monoclonal antibodies

The Journal of biological chemistry, 2017-06, Vol.292 (23), p.9551-9566

2017

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Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE

Clinical immunology (Orlando, Fla.), 2016-08, Vol.169, p.58-68

2016

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Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination

Nature communications, 2024-10, Vol.15 (1), p.8702, Article 8702

2024

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Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma

Frontiers in immunology, 2020-03, Vol.11, p.398-398

2020

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B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis

The Journal of immunology (1950), 2019-02, Vol.202 (3), p.664-674

2019

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Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome

Biochemical and biophysical research communications, 2017-09, Vol.491 (2), p.296-302

2017

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Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling

Cytokine (Philadelphia, Pa.), 2017-04, Vol.92, p.118-123

2017

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Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Science immunology, 2020-07, Vol.5 (49)

2020

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ADAM10 inhibits the interaction between IL-17 and HMGB1 in Buerger's disease

European review for medical and pharmacological sciences, 2021-06, Vol.25 (11), p.4051

2021

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Serological immune response against ADAM10 pro-domain is associated with favourable prognosis in stage III colorectal cancer patients

Oncotarget, 2016-11, Vol.7 (48), p.80059-80076

2016

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Tspan33 is Expressed in Transitional and Memory B Cells, but is not Responsible for High ADAM10 Expression

Scandinavian journal of immunology, 2017-07, Vol.86 (1), p.23-30

2017

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Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis

Journal of Alzheimer's disease, 2016-01, Vol.51 (1), p.179-195

2016

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Shed it, and help-LAG3 cleavage drives conventional CD4 + T cells to overcome resistance to PD-1 immunotherapy

Science immunology, 2020-07, Vol.5 (49)

2020

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ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses

The Journal of immunology (1950), 2017-10, Vol.199 (7), p.2305-2315

2017

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Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

Cell reports (Cambridge), 2016-02, Vol.14 (7), p.1761-1773

2016

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Shedding of endogenous MHC class I‐related chain molecules A and B from different human tumor entities: Heterogeneous involvement of the “a disintegrin and metalloproteases” 10 and 17

International journal of cancer, 2013-10, Vol.133 (7), p.1557-1566

2013

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Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α–converting enzyme

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2725-2734

2018

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α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

Cell host & microbe, 2018-08, Vol.24 (2), p.271-284.e3

2018

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Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis

RNA biology, 2019-11, Vol.16 (11), p.1592-1603

2019

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ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance

Oncoimmunology, 2020-01, Vol.9 (1), p.1744980-1744980

2020

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An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

The Journal of experimental medicine, 2016-08, Vol.213 (9), p.1741-1757

2016

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Regulation of adipose tissue inflammation by interleukin 6

Platelet-Derived Exosomal MicroRNA-25-3p Inhibits Coronary Vascular Endothelial Cell Inflammation Through Adam10 via the NF-κB Signaling Pathway in ApoE -/- Mice

ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration

Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen

New insights into the tetraspanin Tspan5 using novel monoclonal antibodies

Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE

Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination

Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma

B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis

Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome

Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

ADAM10 inhibits the interaction between IL-17 and HMGB1 in Buerger's disease

Serological immune response against ADAM10 pro-domain is associated with favourable prognosis in stage III colorectal cancer patients

Tspan33 is Expressed in Transitional and Memory B Cells, but is not Responsible for High ADAM10 Expression

Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis

Shed it, and help-LAG3 cleavage drives conventional CD4 + T cells to overcome resistance to PD-1 immunotherapy

ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

Shedding of endogenous MHC class I‐related chain molecules A and B from different human tumor entities: Heterogeneous involvement of the “a disintegrin and metalloproteases” 10 and 17

Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α–converting enzyme

α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis

ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

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