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Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics

Drug development research, 2020-08, Vol.81 (5), p.537-540

Gurwitz, David

2020

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Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

The Journal of pathology, 2020-07, Vol.251 (3), p.228-248

2020

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Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2

Journal of medical virology, 2020-06, Vol.92 (6), p.595-601

2020

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Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19

Journal of medical virology, 2020-07, Vol.92 (7), p.726-730

2020

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Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages

Cytometry. Part A, 2023-02, Vol.103 (2), p.136-145

2023

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Cell entry mechanisms of SARS-CoV-2

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (21), p.11727-11734

2020

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Characterization of an engineered ACE2 protein for its improved biological features and its transduction into MSCs: A novel approach to combat COVID-19 infection

International journal of biological macromolecules, 2024-10, Vol.277 (Pt 3), p.134066, Article 134066

2024

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Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution

Acta crystallographica. Section D, Biological crystallography., 2022-09, Vol.78 (9), p.1156-1170

2022

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Body Localization of ACE-2: On the Trail of the Keyhole of SARS-CoV-2

Frontiers in medicine, 2020-12, Vol.7, p.594495-594495

2020

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A comprehensive examination of ACE2 receptor and prediction of spike glycoprotein and ACE2 interaction based on in silico analysis of ACE2 receptor

Journal of biomolecular structure & dynamics, 2024-06, Vol.42 (9), p.4412-4428

2024

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SARS-CoV-2 infection and its effects on the endocrine system

Baillière's best practice & research. Clinical endocrinology & metabolism, 2023-07, Vol.37 (4), p.101761, Article 101761

2023

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Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

Cell discovery, 2020-02, Vol.6 (1), p.11-11, Article 11

2020

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Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (19), p.1

2021

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In vitro antibody-mediated SARS-CoV-2 infection suppression through human ACE2 receptor blockade

Immunology letters, 2024-08, Vol.268, p.106887, Article 106887

2024

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Vitamin D and COVID‐19: Role of ACE2, age, gender, and ethnicity

Journal of medical virology, 2021-09, Vol.93 (9), p.5285-5294

2021

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Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence

Journal of clinical medicine, 2020-05, Vol.9 (5), p.1417

2020

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COVID‐19 and renin‐angiotensin system inhibition: role of angiotensin converting enzyme 2 (ACE2) ‐ Is there any scientific evidence for controversy?

Journal of internal medicine, 2020-10, Vol.288 (4), p.410-421

2020

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Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea

Eye (London), 2020-07, Vol.34 (7), p.1212-1219

2020

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

European journal of human genetics : EJHG, 2020-11, Vol.28 (11), p.1602-1614

2020

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In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

Molecular systems biology, 2020-07, Vol.16 (7), p.e9628-n/a

2020

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Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation

Aging cell, 2020-07, Vol.19 (7), p.n/a

2020

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Comprehensive characterization of N- and O- glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2

Glycobiology (Oxford), 2020-10, Vol.31 (4), p.410-424

2020

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REGULATORY MECHANISMS OF ANGIOTENSIN-CONVERTING ENZYME 2 AND THEIR SIGNIFICANCE IN THE DEVELOPMENT OF SEVERE COVID-19

Problems of infectious and parasitic diseases, 2024-01, Vol.51 (2), p.5-10

2024

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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

BMC medicine, 2020-07, Vol.18 (1), p.216-8, Article 216

2020

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COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3474

2020

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Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2

Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19

Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages

Cell entry mechanisms of SARS-CoV-2

Characterization of an engineered ACE2 protein for its improved biological features and its transduction into MSCs: A novel approach to combat COVID-19 infection

Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution

Body Localization of ACE-2: On the Trail of the Keyhole of SARS-CoV-2

A comprehensive examination of ACE2 receptor and prediction of spike glycoprotein and ACE2 interaction based on in silico analysis of ACE2 receptor

SARS-CoV-2 infection and its effects on the endocrine system

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike

In vitro antibody-mediated SARS-CoV-2 infection suppression through human ACE2 receptor blockade

Vitamin D and COVID‐19: Role of ACE2, age, gender, and ethnicity

Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence

COVID‐19 and renin‐angiotensin system inhibition: role of angiotensin converting enzyme 2 (ACE2) ‐ Is there any scientific evidence for controversy?

Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea

ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation

Comprehensive characterization of N- and O- glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2

REGULATORY MECHANISMS OF ANGIOTENSIN-CONVERTING ENZYME 2 AND THEIR SIGNIFICANCE IN THE DEVELOPMENT OF SEVERE COVID-19

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?

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