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Structural pharmacology and therapeutic potential of 5-methoxytryptamines

Nature (London), 2024-06, Vol.630 (8015), p.237-246

2024

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Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro

Molecular and cellular endocrinology, 2015-03, Vol.404, p.1-8

2015

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N‑Benzyl-5-methoxytryptamines as Potent Serotonin 5‑HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues

ACS chemical neuroscience, 2015-07, Vol.6 (7), p.1165-1175

2015

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The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury

International journal of molecular sciences, 2016-06, Vol.17 (6), p.935-935

2016

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Trends in DMT and other tryptamine use among young adults in the United States

The American journal on addictions, 2018-10, Vol.27 (7), p.578-585

2018

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5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines

PloS one, 2019-01, Vol.14 (1), p.e0209804-e0209804

2019

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Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells

International journal of molecular sciences, 2018-11, Vol.19 (12), p.3786

2018

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The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system

Biochemical and biophysical research communications, 2012-07, Vol.423 (4), p.873-877

2012

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MT1 Melatonin Receptors Mediate Somatic, Behavioral, and Reproductive Neuroendocrine Responses to Photoperiod and Melatonin in Siberian Hamsters (Phodopus sungorus)

Endocrinology (Philadelphia), 2010-02, Vol.151 (2), p.714-721

Prendergast, Brian J

2010

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Hallucinogen-like actions of 5-methoxy- N, N-diisopropyltryptamine in mice and rats

Pharmacology, biochemistry and behavior, 2006, Vol.83 (1), p.122-129

2006

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Role of peripheral 5-HT 5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats

Scientific reports, 2020-11, Vol.10 (1), p.19358

2020

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Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs

Journal of pineal research, 2002-08, Vol.33 (1), p.20-30

2002

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Functional activity of serotoninergic and melatoninergic systems expressed in the skin

Journal of cellular physiology, 2003-07, Vol.196 (1), p.144-153

2003

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Effects of early serotonin programming on behavior and central monoamine concentrations in an avian model

Behavioural brain research, 2013-09, Vol.253, p.290-296

2013

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Alterations in Body Temperature, Corticosterone, and Behavior Following the Administration of 5-Methoxy-Diisopropyltryptamine ('Foxy') to Adult Rats: a New Drug of Abuse

Neuropsychopharmacology (New York, N.Y.), 2007-06, Vol.32 (6), p.1404-1420

2007

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Activation of the Ah Receptor by Tryptophan and Tryptophan Metabolites

Biochemistry (Easton), 1998-08, Vol.37 (33), p.11508-11515

1998

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Synthesis and preliminary screening of novel tryptamines as 5-HT4 receptor ligands

Current medicinal chemistry, 2010-09, Vol.17 (25), p.2775-2787

2010

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Early Serotonergic Projections to Cajal-Retzius Cells: Relevance for Cortical Development

The Journal of neuroscience, 2004-02, Vol.24 (7), p.1652-1659

2004

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5-Methoxy- N, N-diisopropyltryptamine (Foxy), a selective and high affinity inhibitor of serotonin transporter

Toxicology letters, 2007-04, Vol.170 (1), p.75-82

2007

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The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors

Neuroscience, 2000-01, Vol.101 (2), p.459-469

2000

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Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors

Journal of pharmacy and pharmacology, 2012-08, Vol.64 (8), p.1099-1106

2012

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5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats

Neuropharmacology, 2005-09, Vol.49 (3), p.367

2005

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Autoradiographic distribution of 5‐HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species

British journal of pharmacology, 2004-01, Vol.141 (1), p.92-104

2004

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The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in ω-3 polyunsaturated fatty acids

Life sciences (1973), 2007-07, Vol.81 (4), p.299-305

2007

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Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells

Neuropharmacology, 2005-07, Vol.49 (1), p.40-47

2005

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Structural pharmacology and therapeutic potential of 5-methoxytryptamines

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro

N‑Benzyl-5-methoxytryptamines as Potent Serotonin 5‑HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues

The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury

Trends in DMT and other tryptamine use among young adults in the United States

5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines

Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells

The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system

MT1 Melatonin Receptors Mediate Somatic, Behavioral, and Reproductive Neuroendocrine Responses to Photoperiod and Melatonin in Siberian Hamsters (Phodopus sungorus)

Hallucinogen-like actions of 5-methoxy- N, N-diisopropyltryptamine in mice and rats

Role of peripheral 5-HT 5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats

Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

Effects of early serotonin programming on behavior and central monoamine concentrations in an avian model

Alterations in Body Temperature, Corticosterone, and Behavior Following the Administration of 5-Methoxy-Diisopropyltryptamine ('Foxy') to Adult Rats: a New Drug of Abuse

Activation of the Ah Receptor by Tryptophan and Tryptophan Metabolites

Synthesis and preliminary screening of novel tryptamines as 5-HT4 receptor ligands

Early Serotonergic Projections to Cajal-Retzius Cells: Relevance for Cortical Development

5-Methoxy- N, N-diisopropyltryptamine (Foxy), a selective and high affinity inhibitor of serotonin transporter

The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors

Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors

5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats

Autoradiographic distribution of 5‐HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species

The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in ω-3 polyunsaturated fatty acids

Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells

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