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4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Chemical Biology to Agrochemicals
Journal of agricultural and food chemistry, 2017-10, Vol.65 (39), p.8523-8537
2017
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Discovery of N‑Aroyl Diketone/Triketone Derivatives as Novel 4‑Hydroxyphenylpyruvate Dioxygenase Inhibiting-Based Herbicides
Journal of agricultural and food chemistry, 2019-10, Vol.67 (43), p.11839-11847
2019
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Improved Herbicide Resistance of 4‑Hydroxyphenylpyruvate Dioxygenase from Sphingobium sp. TPM-19 through Directed Evolution
Journal of agricultural and food chemistry, 2020-11, Vol.68 (44), p.12365-12374
2020
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Discovery of Novel Pyrazole–Quinazoline-2,4-dione Hybrids as 4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors
Journal of agricultural and food chemistry, 2020-05, Vol.68 (18), p.5059-5067
2020
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Insights into 4-hydroxyphenylpyruvate dioxygenase-inhibitor interactions from comparative structural biology
Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-06, Vol.48 (6), p.568-584
2023
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Design, Synthesis, and Biological Activity of Novel Triketone-Containing Phenoxy Nicotinyl Inhibitors of HPPD
Journal of agricultural and food chemistry, 2024-05, Vol.72 (20), p.11321-11330
2024
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Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations
The FEBS journal, 2019-03, Vol.286 (5), p.975-990
2019
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Synthesis and Herbicidal Evaluation of Triketone-Containing Quinazoline-2,4-diones
Journal of agricultural and food chemistry, 2014-12, Vol.62 (49), p.11786-11796
2014
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Pyomelanin production via heterologous expression of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and construction of HPPD inhibitor screening model
Journal of bioscience and bioengineering, 2023-02, Vol.135 (2), p.93-101
2023
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Inhibition of 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE expression by brassinosteroid reduces carotenoid accumulation in Arabidopsis
Journal of experimental botany, 2022-03, Vol.73 (5), p.1415-1428
2022
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Crystal structure of HPPD inhibitor sensitive protein from Oryza sativa
Biochemical and biophysical research communications, 2024-04, Vol.704, p.149672-149672, Article 149672
2024
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Synthesis and Herbicidal Activity of Triketone–Quinoline Hybrids as Novel 4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors
Journal of agricultural and food chemistry, 2015-06, Vol.63 (23), p.5587-5596
2015
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An Efficient One-Pot Synthesis of 2‑(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4‑Hydroxyphenylpyruvate Dioxygenase Inhibitors
Journal of agricultural and food chemistry, 2016-11, Vol.64 (47), p.8986-8993
2016
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Cloning of a novel topramezone-resistant 4-hydroxyphenylpyruvate dioxygenase gene and improvement of its resistance through pressure acclimation
Enzyme and microbial technology, 2020-10, Vol.140, p.109642, Article 109642
2020
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4-Hydroxyphenylpyruvate dioxygenase from sea cucumber Apostichopus japonicus negatively regulates reactive oxygen species production
Fish & shellfish immunology, 2020-06, Vol.101, p.261-268
2020
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4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: Exemplars of the α-keto acid dependent oxygenases
Archives of biochemistry and biophysics, 2014-02, Vol.544, p.58-68
2014
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Broad 4-Hydroxyphenylpyruvate Dioxygenase Inhibitor Herbicide Tolerance in Soybean with an Optimized Enzyme and Expression Cassette
Plant physiology (Bethesda), 2014-11, Vol.166 (3), p.1162-1176
2014
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Herbicidal 4-hydroxyphenylpyruvate dioxygenase inhibitors—A review of the triketone chemistry story from a Syngenta perspective
Bioorganic & medicinal chemistry, 2009-06, Vol.17 (12), p.4134-4152
2009
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Design, synthesis and herbicidal activity of novel quinazoline‐2,4‐diones as 4‐hydroxyphenylpyruvate dioxygenase inhibitors
Pest management science, 2015-08, Vol.71 (8), p.1122-1132
2015
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A rice gene that confers broad-spectrum resistance to β-triketone herbicides
Science (American Association for the Advancement of Science), 2019-07, Vol.365 (6451), p.393-396
2019
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Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone
Annals of the rheumatic diseases, 2014-01, Vol.73 (1), p.284-289
2014
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Effects of HPPD inhibitor herbicides on soybean root exudates: A combination study of multispectral technique and 2D-COS analysis
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2023-03, Vol.289, p.122241, Article 122241
2023
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4‑Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases
Journal of medicinal chemistry, 2017-05, Vol.60 (10), p.4101-4125
2017
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4-Hydroxyphenylpyruvate dioxygenase
Archives of biochemistry and biophysics, 2005, Vol.433 (1), p.117-128
2005
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Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide
Journal of agricultural and food chemistry, 2021-01, Vol.69 (1), p.459-473
2021
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