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Cholesterol Metabolites Alleviate Injured Liver Function and Decrease Mortality in an LPS-Induced Mouse Model

Metabolism, clinical and experimental, 2017-06, Vol.71, p.83-93

2017

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25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Free radical biology & medicine, 2024-11, Vol.224, p.232-245

2024

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Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol

Journal of lipid research, 2023-04, Vol.64 (4), p.100350, Article 100350

2023

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Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation

Cell, 2017-11, Vol.171 (5), p.1057-1071.e11

2017

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27-Hydroxycholesterol inhibits rhinovirus replication in vitro and on human nasal and bronchial histocultures without selecting viral resistant variants

Antiviral research, 2022-08, Vol.204, p.105368-105368, Article 105368

2022

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CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells

Cell chemical biology, 2024-07, Vol.31 (7), p.1277-1289.e7

2024

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A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection

The Journal of infectious diseases, 2022-06, Vol.225 (12), p.2219-2228

2022

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Research progress on the mechanism of cholesterol-25-hydroxylase in intestinal immunity

Frontiers in immunology, 2023-08, Vol.14, p.1241262-1241262

2023

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25-Hydroxycholesterol induces oxidative stress, leading to apoptosis and ferroptosis in extravillous trophoblasts

Chemico-biological interactions, 2024-11, Vol.403, p.111214, Article 111214

2024

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Antiviral role of cholesterol 25-hydroxylase in inhibiting porcine circovirus 3 replication

Veterinary microbiology, 2024-11, Vol.298, p.110284, Article 110284

2024

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25 (S)-Hydroxycholesterol acts as a possible dual enzymatic inhibitor of SARS-CoV-2 Mpro and RdRp-: an insight from molecular docking and dynamics simulation approaches

Journal of biomolecular structure & dynamics, 2023-07, Vol.41 (10), p.4744-4755

2023

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Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol

Journal of lipid research, 2023-04, Vol.64 (4), p.100350-100350

2023

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25-Hydroxycholesterol in health and diseases

Journal of lipid research, 2024-01, Vol.65 (1), p.100486, Article 100486

2024

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The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Immunity (Cambridge, Mass.), 2021-10, Vol.54 (10), p.2273-2287.e6

2021

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Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol

Frontiers in microbiology, 2023-06, Vol.14, p.1178005-1178005

2023

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Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates isolated from cataractous human lens via different mechanisms

Biochemical and biophysical research communications, 2018-12, Vol.506 (4), p.868-873

2018

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Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury

Neural regeneration research, 2023-06, Vol.18 (6), p.1339-1346

2023

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Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm

Nano today, 2021-06, Vol.38, p.101149-101149, Article 101149

2021

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Immune-related oxysterol modulates neuromuscular transmission via non-genomic liver X receptor-dependent mechanism

Free radical biology & medicine, 2021-10, Vol.174, p.121-134

2021

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Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins

European journal of pharmacology, 2022-07, Vol.926, p.175033-175033, Article 175033

2022

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A randomized clinical trial in vitamin D–deficient adults comparing replenishment with oral vitamin D3 with narrow-band UV type B light: effects on cholesterol and the transcriptional profiles of skin and blood1,2

The American journal of clinical nutrition, 2017-05, Vol.105 (5), p.1230-1238

2017

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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

Immunity (Cambridge, Mass.), 2024-05, Vol.57 (5), p.1087-1104.e7

2024

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25-hydroxycholesterol triggers antioxidant signaling in mouse atria

Prostaglandins & other lipid mediators, 2024-06, Vol.172, p.106834-106834, Article 106834

2024

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Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol

Biochimica et biophysica acta. Biomembranes, 2019-01, Vol.1861 (1), p.228-235

2019

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Cholesterol Metabolites Alleviate Injured Liver Function and Decrease Mortality in an LPS-Induced Mouse Model

25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol

Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation

27-Hydroxycholesterol inhibits rhinovirus replication in vitro and on human nasal and bronchial histocultures without selecting viral resistant variants

CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells

An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles

A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection

Research progress on the mechanism of cholesterol-25-hydroxylase in intestinal immunity

25-Hydroxycholesterol induces oxidative stress, leading to apoptosis and ferroptosis in extravillous trophoblasts

Antiviral role of cholesterol 25-hydroxylase in inhibiting porcine circovirus 3 replication

25 (S)-Hydroxycholesterol acts as a possible dual enzymatic inhibitor of SARS-CoV-2 Mpro and RdRp-: an insight from molecular docking and dynamics simulation approaches

Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol

25-Hydroxycholesterol in health and diseases

The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol

Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates isolated from cataractous human lens via different mechanisms

Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury

Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm

Immune-related oxysterol modulates neuromuscular transmission via non-genomic liver X receptor-dependent mechanism

Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins

A randomized clinical trial in vitamin D–deficient adults comparing replenishment with oral vitamin D3 with narrow-band UV type B light: effects on cholesterol and the transcriptional profiles of skin and blood1,2

25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

25-hydroxycholesterol triggers antioxidant signaling in mouse atria

Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol

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