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CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

Nature medicine, 2018-06, Vol.24 (6), p.731-738

2018

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Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

Journal of clinical immunology, 2012-10, Vol.32 (5), p.1059-1070

2012

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The pharmacology of second-generation chimeric antigen receptors

Nature reviews. Drug discovery, 2015-07, Vol.14 (7), p.499-509

2015

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CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Nature (London), 2019-04, Vol.568 (7750), p.112-116

2019

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Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Nature (London), 2017-03, Vol.543 (7643), p.113-117

2017

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Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

Cancer cell, 2015-10, Vol.28 (4), p.415-428

2015

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HLA-independent T cell receptors for targeting tumors with low antigen density

Nature medicine, 2022-02, Vol.28 (2), p.345-352

2022

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Development and Validation of a Good Manufacturing Process for IL-4-Driven Expansion of Chimeric Cytokine Receptor-Expressing CAR T-Cells

Cells (Basel, Switzerland), 2021-07, Vol.10 (7), p.1797

2021

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Selective Expansion of Chimeric Antigen Receptor-targeted T-cells with Potent Effector Function using Interleukin-4

The Journal of biological chemistry, 2010-08, Vol.285 (33), p.25538-25544

2010

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Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity?

The Journal of immunology (1950), 2013-11, Vol.191 (9), p.4589-4598

2013

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Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Nature biomedical engineering, 2022-11, Vol.6 (11), p.1284-1297

2022

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Flexible targeting of ErbB dimers that drive tumorigenesis by using genetically engineered T cells

Molecular medicine (Cambridge, Mass.), 2012-04, Vol.18 (4), p.565-576

2012

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Engineered and banked iPSCs for advanced NK- and T-cell immunotherapies

Blood, 2023-02, Vol.141 (8), p.846-855

2023

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Synergistic Chemoimmunotherapy of Epithelial Ovarian Cancer Using ErbB-Retargeted T Cells Combined with Carboplatin

The Journal of immunology (1950), 2013-09, Vol.191 (5), p.2437-2445

2013

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CAR T-cell immunotherapy of MET-expressing malignant mesothelioma

Oncoimmunology, 2017-12, Vol.6 (12), p.e1363137-e1363137

2017

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Unraveling barriers to iPSC-derived CAR-T cell differentiation

Cell stem cell, 2023-03, Vol.30 (3), p.248-249

2023

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The Pluripotent Path to Immunotherapy

Experimental hematology, 2024-11, Vol.139, p.104648, Article 104648

2024

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T cells fail to develop in the human skin-cell explants system; an inconvenient truth

BMC immunology, 2011-02, Vol.12 (1), p.17-17, Article 17

2011

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Adoptive immunotherapy of epithelial ovarian cancer with Vγ9Vδ2 T cells, potentiated by liposomal alendronic acid

The Journal of immunology (1950), 2014-12, Vol.193 (11), p.5557-5566

2014

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Adoptive Immunotherapy of Epithelial Ovarian Cancer with V gamma 9V delta 2 T Cells, Potentiated by Liposomal Alendronic Acid

The Journal of immunology (1950), 2014-12, Vol.193 (11), p.5557-5566

2014

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Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Nature biomedical engineering, 2024-02

2024

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Adoptive Cell Therapy from the Dish: Potentiating Induced Pluripotent Stem Cells

Transfusion medicine and hemotherapy, 2024-08, p.1-15

2024

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Abstract 2309: T-cell development from T cell-derived induced pluripotent stem cell

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2309-2309

2016

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CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

The pharmacology of second-generation chimeric antigen receptors

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection

Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

HLA-independent T cell receptors for targeting tumors with low antigen density

Development and Validation of a Good Manufacturing Process for IL-4-Driven Expansion of Chimeric Cytokine Receptor-Expressing CAR T-Cells

Selective Expansion of Chimeric Antigen Receptor-targeted T-cells with Potent Effector Function using Interleukin-4

Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity?

Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Flexible targeting of ErbB dimers that drive tumorigenesis by using genetically engineered T cells

Engineered and banked iPSCs for advanced NK- and T-cell immunotherapies

Synergistic Chemoimmunotherapy of Epithelial Ovarian Cancer Using ErbB-Retargeted T Cells Combined with Carboplatin

CAR T-cell immunotherapy of MET-expressing malignant mesothelioma

Unraveling barriers to iPSC-derived CAR-T cell differentiation

The Pluripotent Path to Immunotherapy

T cells fail to develop in the human skin-cell explants system; an inconvenient truth

Adoptive immunotherapy of epithelial ovarian cancer with Vγ9Vδ2 T cells, potentiated by liposomal alendronic acid

Adoptive Immunotherapy of Epithelial Ovarian Cancer with V gamma 9V delta 2 T Cells, Potentiated by Liposomal Alendronic Acid

Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Adoptive Cell Therapy from the Dish: Potentiating Induced Pluripotent Stem Cells

Abstract 2309: T-cell development from T cell-derived induced pluripotent stem cell

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