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Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development

PloS one, 2013-01, Vol.8 (1), p.e54314-e54314

2013

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An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

Frontiers in immunology, 2021-12, Vol.12, p.781280-781280

2021

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Outer membrane vesicles as platform vaccine technology

Biotechnology journal, 2015-09, Vol.10 (11), p.1689-1706

2015

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Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy

PLoS pathogens, 2009-04, Vol.5 (4), p.e1000396-e1000396

2009

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Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis

Infection and Immunity, 2008-08, Vol.76 (8), p.3801-3807

2008

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Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity

Clinical and Vaccine Immunology, 2010-04, Vol.17 (4), p.487-495

2010

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Opa⁺ and Opa⁻ Isolates of Neisseria meningitidis and Neisseria gonorrhoeae Induce Sustained Proliferative Responses in Human CD4⁺ T Cells

Infection and Immunity, 2009-11, Vol.77 (11), p.5170-5180

2009

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Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease

Infection and Immunity, 2010-07, Vol.78 (7), p.3177-3186

2010

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Identification of a Novel Lipopolysaccharide Core Biosynthesis Gene Cluster in Bordetella pertussis, and Influence of Core Structure and Lipid A Glucosamine Substitution on Endotoxic Activity

Infection and Immunity, 2009-07, Vol.77 (7), p.2602-2611

2009

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Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

Vaccine, 2016-02, Vol.34 (8), p.1025-1033

2016

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Next-generation outer membrane vesicle vaccines against Neisseria meningitidis based on nontoxic LPS mutants

Human vaccines, 2011-08, Vol.7 (8), p.886-890

2011

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Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity

Vaccines (Basel), 2020-10, Vol.8 (4), p.594

2020

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Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

Pharmaceutics, 2021-04, Vol.13 (4), p.501

2021

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Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Vaccine, 2013-02, Vol.31 (9), p.1298-1304

2013

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Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells

Infection and immunity, 2015-01, Vol.83 (1), p.227-238

2015

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Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis

PloS one, 2010-12, Vol.5 (12), p.e15692-e15692

2010

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Agonists of Toll-Like Receptors 3, 4, 7, and 9 Are Candidates for Use as Adjuvants in an Outer Membrane Vaccine against Neisseria meningitidis Serogroup B

Infection and Immunity, 2007-12, Vol.75 (12), p.5939-5946

2007

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Prevalence and clinical course in invasive infections with meningococcal endotoxin variants

PloS one, 2012-11, Vol.7 (11), p.e49295-e49295

2012

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Meningococcal serogroup Y lpxL1 variants from South Africa are associated with clonal complex 23 among young adults

The Journal of infection, 2014-05, Vol.68 (5), p.455-461

2014

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Expression of the Lipopolysaccharide-Modifying Enzymes PagP and PagL Modulates the Endotoxic Activity of Bordetella pertussis

Infection and Immunity, 2006-10, Vol.74 (10), p.5574-5585

2006

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Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production

Innate immunity (London, England), 2011-12, Vol.17 (6), p.517-525

2011

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Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant

The EMBO journal, 2001-12, Vol.20 (24), p.6937-6945

2001

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Meningitis bacterium is viable without endotoxin

Nature (London), 1998-04, Vol.392 (6675), p.449-449

1998

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Crystal Structure and Catalytic Mechanism of the LPS 3-O-Deacylase PagL from Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (18), p.7071-7076

2006

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Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

Expert review of vaccines, 2015-06, Vol.14 (6), p.861-876

2015

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Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

Outer membrane vesicles as platform vaccine technology

Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy

Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis

Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity

Opa⁺ and Opa⁻ Isolates of Neisseria meningitidis and Neisseria gonorrhoeae Induce Sustained Proliferative Responses in Human CD4⁺ T Cells

Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease

Identification of a Novel Lipopolysaccharide Core Biosynthesis Gene Cluster in Bordetella pertussis, and Influence of Core Structure and Lipid A Glucosamine Substitution on Endotoxic Activity

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

Next-generation outer membrane vesicle vaccines against Neisseria meningitidis based on nontoxic LPS mutants

Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells

Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis

Agonists of Toll-Like Receptors 3, 4, 7, and 9 Are Candidates for Use as Adjuvants in an Outer Membrane Vaccine against Neisseria meningitidis Serogroup B

Prevalence and clinical course in invasive infections with meningococcal endotoxin variants

Meningococcal serogroup Y lpxL1 variants from South Africa are associated with clonal complex 23 among young adults

Expression of the Lipopolysaccharide-Modifying Enzymes PagP and PagL Modulates the Endotoxic Activity of Bordetella pertussis

Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production

Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant

Meningitis bacterium is viable without endotoxin

Crystal Structure and Catalytic Mechanism of the LPS 3-O-Deacylase PagL from Pseudomonas aeruginosa

Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

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