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N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection

PloS one, 2017-01, Vol.12 (1), p.e0170419

2017

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Developments in bile salt based therapies: A critical overview

Biochemical pharmacology, 2019-03, Vol.161, p.1-13

2019

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Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP

Scientific reports, 2017-11, Vol.7 (1), p.15307-13, Article 15307

2017

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Identification of FDA-approved drugs targeting the Farnesoid X Receptor

Scientific reports, 2019-02, Vol.9 (1), p.2193-2193, Article 2193

2019

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Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease—A Comprehensive Review

Clinical reviews in allergy & immunology, 2015-06, Vol.48 (2-3), p.182-191

2015

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IgG4-Associated Cholangitis: A Comprehensive Review

Clinical reviews in allergy & immunology, 2015-06, Vol.48 (2-3), p.198-206

2015

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Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

Scientific reports, 2017-05, Vol.7 (1), p.1646-9, Article 1646

2017

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Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome

Endocrinology (Philadelphia), 2017-10, Vol.158 (10), p.3307-3318

2017

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A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I

International journal of molecular sciences, 2020-03, Vol.21 (6), p.2136

2020

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Reduced expression of ATP7B affected by Wilson disease–causing mutations is rescued by pharmacological folding chaperones 4‐phenylbutyrate and curcumin

Hepatology (Baltimore, Md.), 2009-12, Vol.50 (6), p.1783-1795

2009

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Homo- and hetero-dimeric architecture of the human liver Na⁺-dependent taurocholate co-transporting protein

Biochemical journal, 2012-02, Vol.441 (3), p.1007-1016

2012

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Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

Hepatology (Baltimore, Md.), 2021-06, Vol.73 (6), p.2577-2585

2021

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Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Hepatology (Baltimore, Md.), 2017-11, Vol.66 (5), p.1631-1643

2017

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Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Hepatology (Baltimore, Md.), 2015-07, Vol.62 (1), p.207-219

2015

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Role of the IgG4-related cholangitis autoantigen annexin A11 in cholangiocyte protection

Journal of hepatology, 2022-02, Vol.76 (2), p.319-331

2022

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Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia

Journal of hepatology, 2021-02, Vol.74 (2), p.428-441

2021

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On the Mechanisms of Biliary Flux

Hepatology (Baltimore, Md.), 2021-12, Vol.74 (6), p.3497-3512

2021

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Folding defects in P‐type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4‐phenylbutyrate

Hepatology (Baltimore, Md.), 2010-01, Vol.51 (1), p.286-296

2010

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Na+‐taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice

Hepatology (Baltimore, Md.), 2018-09, Vol.68 (3), p.1057-1069

2018

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Regulation of TRPV5 and TRPV6 by associated proteins

American journal of physiology. Renal physiology, 2006-06, Vol.290 (6), p.F1295-F1302

2006

Volltextzugriff (PDF)

Mutational analysis of ATP8B1 in patients with chronic pancreatitis

PloS one, 2013-11, Vol.8 (11), p.e80553-e80553

2013

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Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids

Frontiers in immunology, 2024-01, Vol.14, p.1251134-1251134

2024

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Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

Hepatology (Baltimore, Md.), 2020-01, Vol.71 (1), p.247-258

2020

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An Exon-Specific Small Nuclear U1 RNA (ExSpeU1) Improves Hepatic OTC Expression in a Splicing-Defective spf / ash Mouse Model of Ornithine Transcarbamylase Deficiency

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8735

2020

Volltextzugriff (PDF)

The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction

Journal of human genetics, 2018-05, Vol.63 (5), p.683-686

2018

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N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection

Developments in bile salt based therapies: A critical overview

Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP

Identification of FDA-approved drugs targeting the Farnesoid X Receptor

Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease—A Comprehensive Review

IgG4-Associated Cholangitis: A Comprehensive Review

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome

A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I

Reduced expression of ATP7B affected by Wilson disease–causing mutations is rescued by pharmacological folding chaperones 4‐phenylbutyrate and curcumin

Homo- and hetero-dimeric architecture of the human liver Na⁺-dependent taurocholate co-transporting protein

Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Role of the IgG4-related cholangitis autoantigen annexin A11 in cholangiocyte protection

Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia

On the Mechanisms of Biliary Flux

Folding defects in P‐type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4‐phenylbutyrate

Na+‐taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice

Regulation of TRPV5 and TRPV6 by associated proteins

Mutational analysis of ATP8B1 in patients with chronic pancreatitis

Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids

Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

An Exon-Specific Small Nuclear U1 RNA (ExSpeU1) Improves Hepatic OTC Expression in a Splicing-Defective spf / ash Mouse Model of Ornithine Transcarbamylase Deficiency

The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction

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