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Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients

British Journal of Cancer, 1999-08, Vol.81 (2), p.330-335

1999

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Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

Drug resistance updates, 2015-03, Vol.19, p.1-12

2015

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Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme

Oncogene, 2013-03, Vol.32 (12), p.1539-1548

2013

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A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces

Heliyon, 2023-05, Vol.9 (5), p.e15540-e15540, Article e15540

2023

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Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice

Heliyon, 2024-05, Vol.10 (9), p.e29947-e29947, Article e29947

2024

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Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice

The Journal of pharmacology and experimental therapeutics, 2006-07, Vol.318 (1), p.319-327

2006

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Cognitive impact of cytotoxic agents in mice

Psychopharmacology, 2015-01, Vol.232 (1), p.17-37

2015

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Chemotherapy-related cognitive dysfunction: current animal studies and future directions

Brain imaging and behavior, 2013-12, Vol.7 (4), p.453-459

2013

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Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

British journal of cancer, 1999-01, Vol.79 (1), p.108-113

1999

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Cell, 1994-05, Vol.77 (4), p.491-502

1994

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Neurobiological changes by cytotoxic agents in mice

Behavioural brain research, 2016-02, Vol.299, p.19-26

2016

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Strategies to target drugs to gliomas and CNS metastases of solid tumors

Journal of Neurology, 2016-03, Vol.263 (3), p.428-440

2016

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The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients

British journal of cancer, 2001-11, Vol.85 (10), p.1472-1477

2001

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Altered Pharmacokinetics of Vinblastine in Mdr1a P-glycoprotein-Deficient Mice

JNCI : Journal of the National Cancer Institute, 1996-07, Vol.88 (14), p.994-999

1996

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P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo

British journal of cancer, 2003-11, Vol.89 (9), p.1776-1782

2003

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P10.32.B SCREENING FOR OPTIMAL MULTI-TARGET DRUG COMBINATIONS TARGETING THREE MAJOR PROLIFERATION PATHWAYS IN GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2023-09, Vol.25 (Suppl 2), p.ii70-ii70

2023

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Phase I trial and pharmacological study of a 3-hour paclitaxel infusion in children with refractory solid tumours: a SFOP study

British journal of cancer, 2001-03, Vol.84 (5), p.604-610

2001

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Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI

British journal of cancer, 2008-06, Vol.98 (11), p.1784-1789

2008

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16 Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A7-A8

2018

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Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein

European journal of cancer (1990), 2004-05, Vol.40 (8), p.1269-1274

2004

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Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies

European journal of cancer (1990), 2006-12, Vol.42 (18), p.3294-3303

2006

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From Mouse to Man: Predictions of Human Pharmacokinetics of Orally Administered Docetaxel From Preclinical Studies

Journal of clinical pharmacology, 2012-03, Vol.52 (3), p.370-380

2012

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Role of Glutathione in the Export of Compounds from Cells by the Multidrug-Resistance-Associated Protein

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (17), p.7690-7694

1995

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Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice

Investigational new drugs, 2011-10, Vol.29 (5), p.768-776

2011

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PD-0239 PRE-CLINICAL IMPLEMENTATION OF A SMALL ANIMAL IMAGE-GUIDED IRRADIATOR

Radiotherapy and oncology, 2012-05, Vol.103, p.S95-S95

2012

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Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients

Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme

A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces

Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice

Cognitive impact of cytotoxic agents in mice

Chemotherapy-related cognitive dysfunction: current animal studies and future directions

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Neurobiological changes by cytotoxic agents in mice

Strategies to target drugs to gliomas and CNS metastases of solid tumors

The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients

Altered Pharmacokinetics of Vinblastine in Mdr1a P-glycoprotein-Deficient Mice

P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo

P10.32.B SCREENING FOR OPTIMAL MULTI-TARGET DRUG COMBINATIONS TARGETING THREE MAJOR PROLIFERATION PATHWAYS IN GLIOBLASTOMA

Phase I trial and pharmacological study of a 3-hour paclitaxel infusion in children with refractory solid tumours: a SFOP study

Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI

16 Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance

Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein

Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies

From Mouse to Man: Predictions of Human Pharmacokinetics of Orally Administered Docetaxel From Preclinical Studies

Role of Glutathione in the Export of Compounds from Cells by the Multidrug-Resistance-Associated Protein

Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice

PD-0239 PRE-CLINICAL IMPLEMENTATION OF A SMALL ANIMAL IMAGE-GUIDED IRRADIATOR

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