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Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase ( MAO) inhibitors

Clinical and translational science, 2023-10, Vol.16 (10), p.2058-2069

2023

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Special issue: Innovations in Early Clinical Drug Evaluation

Current Reviews in Clinical and Experimental Pharmacology, 2022, Vol.17 (1), p.3-3

2022

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Disproportional inflation of clinical trial costs: why we should care, and what we should do about it

Nature reviews. Drug discovery, 2024-02, Vol.23 (2), p.85-86

2024

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Pharmacology‐Guided Rule‐Based Adaptive Dose Escalation in First‐in‐Human Studies

Clinical pharmacology and therapeutics, 2021-05, Vol.109 (5), p.1326-1333

2021

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Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers

British journal of clinical pharmacology, 2007-05, Vol.63 (5), p.562-574

2007

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Science-based Ethnic Bridging in Drug Development; Review of Recent Precedence and Suggested Steps Forward

Current clinical pharmacology, 2019-01, Vol.14 (3), p.197-207

2019

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Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

Antimicrobial agents and chemotherapy, 2023-04, Vol.67 (4), p.e0162322-e0162322

2023

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Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

Science translational medicine, 2017-04, Vol.9 (387)

2017

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Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants

Antimicrobial agents and chemotherapy, 2024-05, Vol.68 (5), p.e0145523

2024

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Renal glucose excretion as a function of blood glucose concentration in subjects with type 2 diabetes—results of a hyperglycaemic glucose clamp study

Nephrology, dialysis, transplantation, 2006-08, Vol.21 (8), p.2166-2171

2006

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Predictability of Elimination and Excretion of Small Molecules in Animals and Humans, and its Impact on Dosimetry for human ADME Studies with Radiolabeled Drugs

Current Reviews in Clinical and Experimental Pharmacology, 2022, Vol.17 (1), p.26-38

2022

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First-in-Human Study of the Safety, Tolerability, Pharmacokinetics and - Preliminary Dynamics of Neuroprotectant 2-Iminobiotin in Healthy Subjects

Current clinical pharmacology, 2020-01, Vol.15 (2), p.152-163

2020

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First-in-human Phase 1 safety, PK, and PD study of the CDK4/6 inhibitor G1T28

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.2527-2527

2015

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Evaluation of targeted bone marrow arrest by G1T28, a CDK4/6 inhibitor in clinical development to reduce chemotherapy-induced myelosuppression

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.2529-2529

2015

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Meet Our Editorial Board Member

Current clinical pharmacology, 2018-12, Vol.13 (3), p.141-141

Van Hoogdalem, Ewoud-Jan

2018

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Phase 1 Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of APX001 and to Investigate the Effect of Food on APX001 Bioavailability

Open forum infectious diseases, 2017-10, Vol.4 (suppl_1), p.S534-S534

2017

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First-in-Human Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Open forum infectious diseases, 2017-10, Vol.4 (suppl_1), p.S526-S526

2017

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Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase ( MAO) inhibitors

Special issue: Innovations in Early Clinical Drug Evaluation

Disproportional inflation of clinical trial costs: why we should care, and what we should do about it

Pharmacology‐Guided Rule‐Based Adaptive Dose Escalation in First‐in‐Human Studies

Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers

Science-based Ethnic Bridging in Drug Development; Review of Recent Precedence and Suggested Steps Forward

Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants

Renal glucose excretion as a function of blood glucose concentration in subjects with type 2 diabetes—results of a hyperglycaemic glucose clamp study

Predictability of Elimination and Excretion of Small Molecules in Animals and Humans, and its Impact on Dosimetry for human ADME Studies with Radiolabeled Drugs

First-in-Human Study of the Safety, Tolerability, Pharmacokinetics and - Preliminary Dynamics of Neuroprotectant 2-Iminobiotin in Healthy Subjects

First-in-human Phase 1 safety, PK, and PD study of the CDK4/6 inhibitor G1T28

Evaluation of targeted bone marrow arrest by G1T28, a CDK4/6 inhibitor in clinical development to reduce chemotherapy-induced myelosuppression

Meet Our Editorial Board Member

Phase 1 Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of APX001 and to Investigate the Effect of Food on APX001 Bioavailability

First-in-Human Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

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