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Evaluation of simulated driving in comparison to laboratory-based tests to assess the pharmacodynamics of alprazolam and alcohol

Journal of psychopharmacology (Oxford), 2019-07, Vol.33 (7), p.791-800

2019

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The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

Journal of psychopharmacology (Oxford), 2019-02, Vol.33 (2), p.202-209

2019

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Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool

Journal of Psychopharmacology, 2022-12, Vol.36 (12), p.1299-1314

2022

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NS11821, a partial subtype-selective GABAA agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects

Journal of psychopharmacology (Oxford), 2016-03, Vol.30 (3), p.253-262

2016

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Pseudocontinuous arterial spin labeling reveals dissociable effects of morphine and alcohol on regional cerebral blood flow

Journal of cerebral blood flow and metabolism, 2011-05, Vol.31 (5), p.1321-1333

2011

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Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity

NeuroImage (Orlando, Fla.), 2013-09, Vol.78, p.59-67

2013

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Effects of morphine and alcohol on functional brain connectivity during "resting state":A placebo-controlled crossover study in healthy young men

Human brain mapping, 2012-05, Vol.33 (5), p.1003-1018

2012

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Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity

NeuroImage (Orlando, Fla.), 2015-11, Vol.122, p.440-450

2015

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Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation

Human brain mapping, 2017-01, Vol.38 (1), p.308-325

2017

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The impact of “physiological correction” on functional connectivity analysis of pharmacological resting state fMRI

NeuroImage (Orlando, Fla.), 2013-01, Vol.65, p.499-510

2013

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Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers

British journal of clinical pharmacology, 2011-03, Vol.71 (3), p.331-350

2011

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Biomarkers for the effects of cannabis and THC in healthy volunteers

British journal of clinical pharmacology, 2009-01, Vol.67 (1), p.5-21

2009

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Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects

Journal of psychopharmacology (Oxford), 2017-02, Vol.31 (2), p.222-232

2017

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Pharmacokinetic–pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects

British journal of clinical pharmacology, 2011-06, Vol.71 (6), p.886-898

2011

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Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease

NeuroImage (Orlando, Fla.), 2019-10, Vol.199, p.143-152

2019

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Pharmacokinetics and pharmacodynamics of oral mecamylamine – development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation

Journal of psychopharmacology (Oxford), 2017-02, Vol.31 (2), p.192-203

2017

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Pharmacological interactions between brivaracetam and ethanol in healthy males

Journal of psychopharmacology (Oxford), 2017-07, Vol.31 (7), p.915-926

2017

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NS11821, a partial subtype-selective GABA A agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects

Journal of psychopharmacology (Oxford), 2016-03, Vol.30 (3), p.253-262

2016

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Biperiden Challenge Model in Healthy Elderly as Proof‐of‐Pharmacology Tool: A Randomized, Placebo‐Controlled Trial

Journal of clinical pharmacology, 2021-11, Vol.61 (11), p.1466-1478

2021

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Dual orexin receptor antagonism by almorexant does not potentiate impairing effects of alcohol in humans

European neuropsychopharmacology, 2013-02, Vol.23 (2), p.107-117

2013

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3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome

Expert review of clinical immunology, 2010-11, Vol.6 (6), p.867-874

2010

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Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol‐intoxicated volunteers

British journal of clinical pharmacology, 2013-05, Vol.75 (5), p.1328-1339

2013

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Central nervous system effects of the interaction between risperidone (single dose) and the 5‐HT6 antagonist SB742457 (repeated doses) in healthy men

British journal of clinical pharmacology, 2011-06, Vol.71 (6), p.907-916

2011

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Early stage development of the glycine‐1 re‐uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

British journal of clinical pharmacology, 2013-06, Vol.75 (6), p.1455-1467

2013

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Central nervous system effects of alcohol at a pseudo‐steady‐state concentration using alcohol clamping in healthy volunteers

British journal of clinical pharmacology, 2009-10, Vol.68 (4), p.524-534

2009

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Evaluation of simulated driving in comparison to laboratory-based tests to assess the pharmacodynamics of alprazolam and alcohol

The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool

NS11821, a partial subtype-selective GABAA agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects

Pseudocontinuous arterial spin labeling reveals dissociable effects of morphine and alcohol on regional cerebral blood flow

Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity

Effects of morphine and alcohol on functional brain connectivity during "resting state":A placebo-controlled crossover study in healthy young men

Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity

Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation

The impact of “physiological correction” on functional connectivity analysis of pharmacological resting state fMRI

Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers

Biomarkers for the effects of cannabis and THC in healthy volunteers

Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects

Pharmacokinetic–pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects

Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease

Pharmacokinetics and pharmacodynamics of oral mecamylamine – development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation

Pharmacological interactions between brivaracetam and ethanol in healthy males

NS11821, a partial subtype-selective GABA A agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects

Biperiden Challenge Model in Healthy Elderly as Proof‐of‐Pharmacology Tool: A Randomized, Placebo‐Controlled Trial

Dual orexin receptor antagonism by almorexant does not potentiate impairing effects of alcohol in humans

3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome

Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol‐intoxicated volunteers

Central nervous system effects of the interaction between risperidone (single dose) and the 5‐HT6 antagonist SB742457 (repeated doses) in healthy men

Early stage development of the glycine‐1 re‐uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

Central nervous system effects of alcohol at a pseudo‐steady‐state concentration using alcohol clamping in healthy volunteers

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