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Mutational Analysis of the Antagonist-binding Site of the Histamine H1 Receptor

The Journal of biological chemistry, 1999-10, Vol.274 (42), p.29994-30000

1999

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Histaprodifens: Synthesis, Pharmacological in Vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H1-Receptor Agonists

Journal of medicinal chemistry, 2000-03, Vol.43 (6), p.1071-1084

2000

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The Histamine H1-Receptor Antagonist Binding Site. A Stereoselective Pharmacophoric Model Based upon (Semi-)Rigid H1-Antagonists and Including a Known Interaction Site on the Receptor

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3351-3360

1995

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Histaprodifens: Synthesis, Pharmacological in Vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H 1 -Receptor Agonists

Journal of medicinal chemistry, 2000-03, Vol.43 (6), p.1071-1084

2000

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Comparative Evaluation of the Predictive Power of Calculation Procedures for Molecular Lipophilicity

Journal of pharmaceutical sciences, 1995-12, Vol.84 (12), p.1410-1419

1995

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Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors ? An in vitro study

European journal of pharmacology, 1993-03, Vol.232 (2-3), p.199-205

1993

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Is there a difference in the affinity of histamine H 1 receptor antagonists for CNS and peripheral receptors? An in vitro study

European journal of pharmacology, 1993, Vol.232 (2), p.199-205

1993

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Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation

Journal of computer-aided molecular design, 1995-08, Vol.9 (4), p.319-330

1995

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Molecular modelling of asperlicin derived cholecystokinin A receptor antagonists

European journal of pharmacology, 1992-08, Vol.226 (4), p.327-334

1992

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Optically active analogues of ebastine: Synthesis and effect of chirality on their antihistaminic and antimuscarinic activity

Chirality (New York, N.Y.), 1994, Vol.6 (8), p.631-641

1994

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Optical isomers of the H1 antihistamine terfenadine: synthesis and activity

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (8), p.387-390

1991

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ChemInform Abstract: Histaprodifens: Synthesis, Pharmacological in vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H1-Receptor Agonists

ChemInform, 2000-06, Vol.31 (25), p.no-no

2000

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ChemInform Abstract: Histaprodifens: Synthesis, Pharmacological in vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H 1 ‐Receptor Agonists

ChemInform, 2000-06, Vol.31 (25)

2000

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QSAR and Molecular Modelling Studies on Histamine H1-Receptor Antagonists

Quantitative structure-activity relationships, 1992, Vol.11 (3), p.348-363

1992

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QSAR and Molecular Modelling Studies on Histamine H 1 ‐Receptor Antagonists

Quantitative structure-activity relationships, 1992-09, Vol.11 (3), p.348-363

1992

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Predicting Error Bars for QSAR Models

AIP conference proceedings, 2007, Vol.940 (1), p.158-167

2007

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Mutational Analysis of the Antagonist-binding Site of the Histamine H1 Receptor

Histaprodifens: Synthesis, Pharmacological in Vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H1-Receptor Agonists

The Histamine H1-Receptor Antagonist Binding Site. A Stereoselective Pharmacophoric Model Based upon (Semi-)Rigid H1-Antagonists and Including a Known Interaction Site on the Receptor

Histaprodifens: Synthesis, Pharmacological in Vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H 1 -Receptor Agonists

Comparative Evaluation of the Predictive Power of Calculation Procedures for Molecular Lipophilicity

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors ? An in vitro study

Is there a difference in the affinity of histamine H 1 receptor antagonists for CNS and peripheral receptors? An in vitro study

Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation

Molecular modelling of asperlicin derived cholecystokinin A receptor antagonists

Optically active analogues of ebastine: Synthesis and effect of chirality on their antihistaminic and antimuscarinic activity

Optical isomers of the H1 antihistamine terfenadine: synthesis and activity

ChemInform Abstract: Histaprodifens: Synthesis, Pharmacological in vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H1-Receptor Agonists

ChemInform Abstract: Histaprodifens: Synthesis, Pharmacological in vitro Evaluation, and Molecular Modeling of a New Class of Highly Active and Selective Histamine H 1 ‐Receptor Agonists

QSAR and Molecular Modelling Studies on Histamine H1-Receptor Antagonists

QSAR and Molecular Modelling Studies on Histamine H 1 ‐Receptor Antagonists

Predicting Error Bars for QSAR Models

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