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Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

Oncogene, 2014-01, Vol.33 (1), p.97-107

2014

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Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

Oncogene, 2010-03, Vol.29 (9), p.1351-1361

2010

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

Journal of cell science, 2007-03, Vol.120 (6), p.964-972

2007

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Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Oncogene, 2013-08, Vol.32 (31), p.3606-3615

2013

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Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma

Oncogene, 2011-01, Vol.30 (3), p.334-345

2011

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The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC

British journal of cancer, 2015-01, Vol.112 (1), p.122-130

2015

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Bone morphogenetic protein signal transduction in bone

Current medical research and opinion, 2006-01, Vol.22 (S1), p.S7-S11

Dijke, P. ten

2006

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A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Gastro hep advances, 2022, Vol.1 (4), p.678-681

2022

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Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial

Molecular oncology, 2015-06, Vol.9 (6), p.1120-1128

2015

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Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts

Stem cell research, 2019-12, Vol.41, p.101639-101639, Article 101639

2019

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Regulation of Smad signaling by protein kinase C

The FASEB journal, 2001-03, Vol.15 (3), p.553-555

2001

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ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-β/Smad-induced growth arrest of prostate cells

Oncogene, 2006-09, Vol.25 (41), p.5591-5600

2006

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Reversible ubiquitination regulates the Smad/TGF-beta signalling pathway

Biochemical Society transactions, 2006-11, Vol.34 (Pt 5), p.761-763

2006

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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

The Journal of experimental medicine, 2010-01, Vol.207 (1), p.85-100

2010

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Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

The Journal of experimental medicine, 2013, Vol.210 (3), p.563-579

2013

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Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4

The Journal of biological chemistry, 1994-06, Vol.269 (25), p.16985-16988

1994

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SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

Cytokine & growth factor reviews, 2005-06, Vol.16 (3), p.319-327

2005

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

The Journal of experimental medicine, 2004-03, Vol.199 (6), p.805-814

2004

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Distinct and Overlapping Patterns of Localization of Bone Morphogenetic Protein (BMP) Family Members and a BMP Type II Receptor During Fracture Healing in Rats

Bone (New York, N.Y.), 1998-06, Vol.22 (6), p.605-612

1998

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Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta

The Journal of biological chemistry, 1994-08, Vol.269 (31), p.20172-20178

1994

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Expression of TGFβ-family signalling components in ageing cartilage: Age-related loss of TGFβ and BMP receptors

Osteoarthritis and cartilage, 2016-07, Vol.24 (7), p.1235-1245

2016

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Oral administration of GW788388, an inhibitor of TGF-β type I and II receptor kinases, decreases renal fibrosis

Kidney international, 2008-03, Vol.73 (6), p.705-715

2008

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Role of TGF-beta in the tumor stroma

Current cancer drug targets, 2008-09, Vol.8 (6), p.466-472

2008

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TGF-β in aging and disease

Cell and tissue research, 2012-01, Vol.347 (1), p.5-9

2012

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The prognostic role of TGF-β signaling pathway in breast cancer patients

Annals of oncology, 2013-02, Vol.24 (2), p.384-390

2013

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Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC

Bone morphogenetic protein signal transduction in bone

A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial

Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts

Regulation of Smad signaling by protein kinase C

ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-β/Smad-induced growth arrest of prostate cells

Reversible ubiquitination regulates the Smad/TGF-beta signalling pathway

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4

SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

Distinct and Overlapping Patterns of Localization of Bone Morphogenetic Protein (BMP) Family Members and a BMP Type II Receptor During Fracture Healing in Rats

Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta

Expression of TGFβ-family signalling components in ageing cartilage: Age-related loss of TGFβ and BMP receptors

Oral administration of GW788388, an inhibitor of TGF-β type I and II receptor kinases, decreases renal fibrosis

Role of TGF-beta in the tumor stroma

TGF-β in aging and disease

The prognostic role of TGF-β signaling pathway in breast cancer patients

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