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Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines

British Journal of Cancer, 1999-12, Vol.81 (8), p.1285-1293

1999

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RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells

Oncogene, 1999-10, Vol.18 (42), p.5765-5772

1999

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DNA damage is able to induce senescence in tumor cells in vitro and in vivo

Cancer research (Chicago, Ill.), 2002-03, Vol.62 (6), p.1876-1883

2002

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Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance

JNCI : Journal of the National Cancer Institute, 1998-02, Vol.90 (3), p.246-246

1998

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An Efficient System for Active Bovine Pancreatic Ribonuclease Expression in Escherichia coli

Protein expression and purification, 1995-08, Vol.6 (4), p.472-480

1995

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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

PloS one, 2012-01, Vol.7 (1), p.e28568

2012

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The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis

Cell cycle (Georgetown, Tex.), 2007-12, Vol.6 (24), p.3114-3131

2007

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Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase

ChemMedChem, 2021-01, Vol.16 (1), p.113-123

2021

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3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor

Frontiers in microbiology, 2017-06, Vol.8, p.1110-1110

2017

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AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Clinical cancer research, 2012-07, Vol.18 (14), p.3912-3923

2012

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Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (4), p.990-1000

2012

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Cover Feature: Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase (ChemMedChem 1/2021)

ChemMedChem, 2021-01, Vol.16 (1), p.3-3

2021

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Discovery and validation of biomarkers to support clinical development of NXP800: A first-in-class orally active, small-molecule HSF1 pathway inhibitor

European journal of cancer (1990), 2022-10, Vol.174, p.S35-S35

2022

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Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers

Cancer research (Chicago, Ill.), 2011-12, Vol.72 (4), p.990-1000

2011

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Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines

RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells

DNA damage is able to induce senescence in tumor cells in vitro and in vivo

Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance

An Efficient System for Active Bovine Pancreatic Ribonuclease Expression in Escherichia coli

Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis

Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase

3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor

AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Cover Feature: Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar‐Based Molecules that Target Bacterial Glucosyltransferase (ChemMedChem 1/2021)

Discovery and validation of biomarkers to support clinical development of NXP800: A first-in-class orally active, small-molecule HSF1 pathway inhibitor

Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers

Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action distinct from AKT inhibitors

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