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Susceptibility of Leishmania to novel pentavalent organometallics: Investigating impact on DNA and membrane integrity in antimony(III)‐sensitive and ‐resistant strains

Drug development research, 2024-05, Vol.85 (3), p.e22194-n/a

2024

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Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

Microbiology spectrum, 2021-10, Vol.9 (2), p.e0101821-e0101821

2021

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Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery

Genes, 2020-06, Vol.11 (7), p.722

2020

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Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone

Chemical biology & drug design, 2021-01, Vol.97 (1), p.41-50

2021

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Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

Frontiers in cellular and infection microbiology, 2022-08, Vol.12, p.954144-954144

2022

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Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

Parasites & vectors, 2021-08, Vol.14 (1), p.438-438, Article 438

2021

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Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis

PLoS neglected tropical diseases, 2011-05, Vol.5 (5), p.e1167

2011

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Validation of a colorimetric LAMP to detect Loxosceles experimental envenomation

Toxicon (Oxford), 2022-09, Vol.216, p.50-56

2022

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Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania ( Viannia ) Subgenus

Frontiers in cell and developmental biology, 2017-01, Vol.5, p.24-24

2017

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Planarians as models to investigate the bioactivity of gold(I) complexes in vivo

Scientific reports, 2018-11, Vol.8 (1), p.16180-8, Article 16180

2018

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Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide–alkyne cycloaddition

European journal of medicinal chemistry, 2013-05, Vol.63, p.523-530

2013

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Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors

ACS infectious diseases, 2020-05, Vol.6 (5), p.1121-1139

2020

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Critical loss: the effects of VEuPathDB defunding on global health

The Lancet. Microbe, 2024-09, p.100980, Article 100980

2024

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In silico Thermodynamic Evaluation of the Effectiveness of RT-LAMP Primers for SARS-CoV-2 Variants Detection

The Open COVID Journal, 2024-02, Vol.4 (1)

2024

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Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs

Cell biology international, 2022-11, Vol.46 (11), p.1947-1958

2022

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Recent research brings hope for reshaping the co‐evolutionary arms race against parasitic infectious diseases

Drug development research, 2022-04, Vol.83 (2), p.219-221

2022

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Sex under pressure: stress facilitates Leishmania in vitro hybridization

Trends in parasitology, 2022-04, Vol.38 (4), p.274-276

2022

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Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

Biomedicine & pharmacotherapy, 2021-01, Vol.133, p.111049, Article 111049

2021

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Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

Microorganisms (Basel), 2023-04, Vol.11 (4), p.1043

2023

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The mutation G133D on Leishmania guyanensis AQP1 is highly destabilizing as revealed by molecular modeling and hypo-osmotic shock assay

Biochimica et biophysica acta. Biomembranes, 2021-10, Vol.1863 (10), p.183682-183682, Article 183682

2021

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Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions

Biomedicine & pharmacotherapy, 2018-12, Vol.108, p.1170-1180

2018

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Improved antileishmanial activity of Dppz through complexation with antimony(III) and bismuth(III): investigation of the role of the metal

Molecules (Basel, Switzerland), 2012-10, Vol.17 (11), p.12622-12635

2012

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Silver and Nitrate Oppositely Modulate Antimony Susceptibility through Aquaglyceroporin 1 in Leishmania (Viannia) Species

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4482-4489

2016

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Morphological and physiological changes in Leishmania promastigotes induced by yangambin, a lignan obtained from Ocotea duckei

Experimental parasitology, 2011, Vol.127 (1), p.215-221

2011

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Susceptibility of Leishmania to novel pentavalent organometallics: Investigating impact on DNA and membrane integrity in antimony(III)‐sensitive and ‐resistant strains

Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery

Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone

Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

Optimization and Clinical Validation of Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification, a Fast, Highly Sensitive and Specific COVID-19 Molecular Diagnostic Tool That Is Robust to Detect SARS-CoV-2 Variants of Concern

Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis

Validation of a colorimetric LAMP to detect Loxosceles experimental envenomation

Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania ( Viannia ) Subgenus

Planarians as models to investigate the bioactivity of gold(I) complexes in vivo

Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide–alkyne cycloaddition

Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors

Critical loss: the effects of VEuPathDB defunding on global health

In silico Thermodynamic Evaluation of the Effectiveness of RT-LAMP Primers for SARS-CoV-2 Variants Detection

Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs

Recent research brings hope for reshaping the co‐evolutionary arms race against parasitic infectious diseases

Sex under pressure: stress facilitates Leishmania in vitro hybridization

Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

The mutation G133D on Leishmania guyanensis AQP1 is highly destabilizing as revealed by molecular modeling and hypo-osmotic shock assay

Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions

Improved antileishmanial activity of Dppz through complexation with antimony(III) and bismuth(III): investigation of the role of the metal

Silver and Nitrate Oppositely Modulate Antimony Susceptibility through Aquaglyceroporin 1 in Leishmania (Viannia) Species

Morphological and physiological changes in Leishmania promastigotes induced by yangambin, a lignan obtained from Ocotea duckei

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