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Obesity, kidney dysfunction and hypertension: mechanistic links

Nature reviews. Nephrology, 2019-06, Vol.15 (6), p.367

2019

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Role of leptin and central nervous system melanocortins in obesity hypertension

Current opinion in nephrology and hypertension, 2013-03, Vol.22 (2), p.135-140

2013

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Obesity, kidney dysfunction, and inflammation: interactions in hypertension

Cardiovascular research, 2021-07, Vol.117 (8), p.1859-1876

2021

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Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited

Canadian journal of cardiology, 2020-05, Vol.36 (5), p.671-682

2020

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Chronic central ghrelin infusion reduces blood pressure and heart rate despite increasing appetite and promoting weight gain in normotensive and hypertensive rats

Peptides (New York, N.Y. : 1980), 2013-04, Vol.42, p.35-42

2013

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Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure

Journal of the American Heart Association, 2021-03, Vol.10 (6), p.e018298-e018298

2021

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CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System

Current diabetes reports, 2020-07, Vol.20 (7), p.29-29, Article 29

2020

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Mechanisms of Synergistic Interactions of Diabetes and Hypertension in Chronic Kidney Disease: Role of Mitochondrial Dysfunction and ER Stress

Current hypertension reports, 2020-02, Vol.22 (2), p.15-15, Article 15

2020

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Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons

Hypertension (Dallas, Tex. 1979), 2011-05, Vol.57 (5), p.918-926

2011

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Targeting immunometabolism during cardiorenal injury: roles of conventional and alternative macrophage metabolic fuels

Frontiers in physiology, 2023-04, Vol.14, p.1139296-1139296

2023

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Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats

Psychopharmacology, 2017-09, Vol.234 (17), p.2597-2605

2017

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Immunometabolism, extracellular vesicles and cardiac injury

Frontiers in endocrinology (Lausanne), 2024-01, Vol.14, p.1331284-1331284

2024

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MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome

Biology of sex differences, 2024-07, Vol.15 (1), p.1-21, Article 53

2024

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The brain melanocortin system, sympathetic control, and obesity hypertension

Physiology (Bethesda, Md.), 2014-05, Vol.29 (3), p.196-202

2014

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Changes in ambient temperature elicit divergent control of metabolic and cardiovascular actions by leptin

The FASEB journal, 2017-06, Vol.31 (6), p.2418-2428

2017

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Pyridostigmine restores cardiac autonomic balance after small myocardial infarction in mice

PloS one, 2014-08, Vol.9 (8), p.e104476-e104476

2014

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Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart Failure

Frontiers in cardiovascular medicine, 2022-05, Vol.9, p.859253-859253

2022

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Obesity-Induced Hypertension: Interaction of Neurohumoral and Renal Mechanisms

Circulation research, 2015-03, Vol.116 (6), p.991-1006

2015

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Central Nervous System Actions of Leptin Improve Cardiac Function After Ischemia-Reperfusion: Roles of Sympathetic Innervation and Sex Differences

Journal of the American Heart Association, 2022-11, Vol.11 (21), p.e027081-e027081

2022

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Interaction of Obesity and Hypertension on Cardiac Metabolic Remodeling and Survival Following Myocardial Infarction

Journal of the American Heart Association, 2021-03, Vol.10 (6), p.e018212-e018212

2021

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Role of Proopiomelanocortin Neuron Stat3 in Regulating Arterial Pressure and Mediating the Chronic Effects of Leptin

Hypertension (Dallas, Tex. 1979), 2013-05, Vol.61 (5), p.1066-1074

2013

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Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

American journal of physiology. Regulatory, integrative and comparative physiology, 2012-03, Vol.302 (5), p.R561-R567

2012

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Temporal changes in glucose metabolism reflect polarization in resident and monocyte-derived macrophages after myocardial infarction

Frontiers in cardiovascular medicine, 2023-05, Vol.10, p.1136252-1136252

2023

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Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins

The Journal of biological chemistry, 2010-06, Vol.285 (23), p.17271-17276

2010

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A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin

Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1749-1756

2009

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Obesity, kidney dysfunction and hypertension: mechanistic links

Role of leptin and central nervous system melanocortins in obesity hypertension

Obesity, kidney dysfunction, and inflammation: interactions in hypertension

Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited

Chronic central ghrelin infusion reduces blood pressure and heart rate despite increasing appetite and promoting weight gain in normotensive and hypertensive rats

Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure

CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System

Mechanisms of Synergistic Interactions of Diabetes and Hypertension in Chronic Kidney Disease: Role of Mitochondrial Dysfunction and ER Stress

Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons

Targeting immunometabolism during cardiorenal injury: roles of conventional and alternative macrophage metabolic fuels

Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats

Immunometabolism, extracellular vesicles and cardiac injury

MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome

The brain melanocortin system, sympathetic control, and obesity hypertension

Changes in ambient temperature elicit divergent control of metabolic and cardiovascular actions by leptin

Pyridostigmine restores cardiac autonomic balance after small myocardial infarction in mice

Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart Failure

Obesity-Induced Hypertension: Interaction of Neurohumoral and Renal Mechanisms

Central Nervous System Actions of Leptin Improve Cardiac Function After Ischemia-Reperfusion: Roles of Sympathetic Innervation and Sex Differences

Interaction of Obesity and Hypertension on Cardiac Metabolic Remodeling and Survival Following Myocardial Infarction

Role of Proopiomelanocortin Neuron Stat3 in Regulating Arterial Pressure and Mediating the Chronic Effects of Leptin

Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

Temporal changes in glucose metabolism reflect polarization in resident and monocyte-derived macrophages after myocardial infarction

Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins

A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin

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