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The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?

Pharmaceutical research, 2016-09, Vol.33 (9), p.2239-2249

2016

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BAX 335 hemophilia B gene therapy clinical trial results: potential impact of CpG sequences on gene expression

Blood, 2021-02, Vol.137 (6), p.763-774

2021

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Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (7), p.3058-3063

2010

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Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors

Molecular therapy. Methods & clinical development, 2019-09, Vol.14, p.126-133

2019

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Expression of the Integrin αEβ7Identifies Unique Subsets of CD25+as Well as CD25-Regulatory T Cells

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13031-13036

2002

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IL-2 induces in vivo suppression by CD4⁺CD25⁺Foxp3⁺ regulatory T cells

European journal of immunology, 2008-06, Vol.38 (6), p.1643-1653

2008

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Production of therapeutic levels of human FIX-R338L by engineered B cells using GMP-compatible medium

Molecular therapy. Methods & clinical development, 2023-12, Vol.31, p.101111-101111, Article 101111

2023

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Detection of Biologically Relevant Low-Titer Neutralizing Antibodies Against Adeno-Associated Virus Require Sensitive In Vitro Assays

Human gene therapy. Part B. Methods, 2019-04, Vol.30 (2), p.35

2019

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Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

Molecular therapy. Methods & clinical development, 2024-06, Vol.32 (2), p.101255-101255, Article 101255

2024

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Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency

Molecular therapy. Methods & clinical development, 2020-12, Vol.19, p.486-495

2020

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Blockade of the costimulatory CD28‐B7 family signal axis enables repeated application of AAV8 gene vectors

Journal of thrombosis and haemostasis, 2020-05, Vol.18 (5), p.1075-1080

2020

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Interleukin‐2 is essential for CD4+CD25+ regulatory T cell function

European journal of immunology, 2004-09, Vol.34 (9), p.2480-2488

2004

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Co-Prevalence of Pre-Existing Immunity to Different Serotypes of Adeno-Associated Virus (AAV) in Adults with Hemophilia

Blood, 2019-11, Vol.134 (Supplement_1), p.3349-3349

2019

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The Factor VIII Variant X5 Enhances Hemophilia a Gene Therapy Efficiency By Its Improved Secretion

Blood, 2019-11, Vol.134 (Supplement_1), p.3356-3356

2019

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Expression of the integrin alpha(E)beta(7) identifies unique subsets of CD25+ as well as CD25- regulatory T cells

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13031

2002

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Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

The Journal of experimental medicine, 2004-02, Vol.199 (3), p.303-313

2004

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Development of a Transgenic Mouse Model with Immune Tolerance for Human Coagulation Factor VIIa

Pharmaceutical research, 2013-11, Vol.30 (11), p.2855-2867

2013

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Induction and Break of Immune Tolerance to Human FVIII in a HLA-DRB11501 Humanized Hemophilic Mouse Model

Blood, 2011-11, Vol.118 (21), p.2280-2280

2011

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Deciphering of CD4+ T Cell Subsets Involved in Maintenance and Break of Immune Tolerance in a Humanized Mouse Model That Is Immune Tolerant to Human FVII

Blood, 2011-11, Vol.118 (21), p.2188-2188

2011

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Detection of Cellular Immunity to Viral Capsids and Transgene Proteins

Drug Development for Gene Therapy, 2024, p.271-290

2024

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Interleukin-2 is essential for CD4 super(+)CD25 super(+) regulatory T cell function

European Journal of Immunology, 2004-01, Vol.34 (9), p.2480-2488

2004

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Sa.51. The Molecular Basis of Functional Stability of Regulatory T-Cells: The Memory of TH Cells for IL-10 Expression Is Conditional Unless the Gene Is Imprinted by Gata-3

Clinical immunology (Orlando, Fla.), 2006, Vol.119, p.S122-S123

2006

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Expression of the integrin α E β 7 identifies unique subsets of CD25 + as well as CD25 − regulatory T cells

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13031-13036

2002

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Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13031-13036

2002

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The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?

BAX 335 hemophilia B gene therapy clinical trial results: potential impact of CpG sequences on gene expression

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments

Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors

Expression of the Integrin αEβ7Identifies Unique Subsets of CD25+as Well as CD25-Regulatory T Cells

IL-2 induces in vivo suppression by CD4⁺CD25⁺Foxp3⁺ regulatory T cells

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

Production of therapeutic levels of human FIX-R338L by engineered B cells using GMP-compatible medium

Detection of Biologically Relevant Low-Titer Neutralizing Antibodies Against Adeno-Associated Virus Require Sensitive In Vitro Assays

Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency

Blockade of the costimulatory CD28‐B7 family signal axis enables repeated application of AAV8 gene vectors

Interleukin‐2 is essential for CD4+CD25+ regulatory T cell function

Co-Prevalence of Pre-Existing Immunity to Different Serotypes of Adeno-Associated Virus (AAV) in Adults with Hemophilia

The Factor VIII Variant X5 Enhances Hemophilia a Gene Therapy Efficiency By Its Improved Secretion

Expression of the integrin alpha(E)beta(7) identifies unique subsets of CD25+ as well as CD25- regulatory T cells

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

Development of a Transgenic Mouse Model with Immune Tolerance for Human Coagulation Factor VIIa

Induction and Break of Immune Tolerance to Human FVIII in a HLA-DRB11501 Humanized Hemophilic Mouse Model

Deciphering of CD4+ T Cell Subsets Involved in Maintenance and Break of Immune Tolerance in a Humanized Mouse Model That Is Immune Tolerant to Human FVII

Detection of Cellular Immunity to Viral Capsids and Transgene Proteins

Interleukin-2 is essential for CD4 super(+)CD25 super(+) regulatory T cell function

Sa.51. The Molecular Basis of Functional Stability of Regulatory T-Cells: The Memory of TH Cells for IL-10 Expression Is Conditional Unless the Gene Is Imprinted by Gata-3

Expression of the integrin α E β 7 identifies unique subsets of CD25 + as well as CD25 − regulatory T cells

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

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