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Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Hepatology (Baltimore, Md.), 2017-11, Vol.66 (5), p.1631-1643

2017

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Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn's disease

Scientific reports, 2020-11, Vol.10 (1), p.18879, Article 18879

2020

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Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

The Journal of clinical investigation, 2012-02, Vol.122 (2), p.519-528

2012

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Reduced spontaneous itch in mouse models of cholestasis

Scientific reports, 2021-03, Vol.11 (1), p.6127-6127, Article 6127

2021

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Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Hepatology (Baltimore, Md.), 2015-07, Vol.62 (1), p.207-219

2015

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Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human Cholangiocytes

Hepatology (Baltimore, Md.), 2016-08, Vol.64 (2), p.522-534

2016

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Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

JHEP reports, 2022-11, Vol.4 (11), p.100573-100573, Article 100573

2022

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Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1−/−Ldlr−/− mice

Journal of lipid research, 2024-08, Vol.65 (8), p.100594, Article 100594

2024

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Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice

Journal of hepatology, 2019-07, Vol.71 (1), p.153-162

2019

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Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs

Pharmacological research, 2023-04, Vol.190, p.106724-106724, Article 106724

2023

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Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116644, Article 116644

2024

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Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients

Molecular therapy. Methods & clinical development, 2021-03, Vol.20, p.287-297

2021

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Adeno-associated viral vector serotype 5 poorly transduces liver in rat models

PloS one, 2013-12, Vol.8 (12), p.e82597-e82597

2013

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The transcriptomic signature of fasting murine liver

BMC genomics, 2008-11, Vol.9 (1), p.528-528, Article 528

2008

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Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

Scientific reports, 2017-05, Vol.7 (1), p.1646-9, Article 1646

2017

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Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning

Developmental biology, 2014-12, Vol.396 (2), p.201-213

2014

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ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

Hepatology (Baltimore, Md.), 2016-07, Vol.64 (1), p.161-174

2016

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Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein

The Journal of pharmacology and experimental therapeutics, 2010-07, Vol.334 (1), p.78

2010

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Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein

Journal of lipid research, 2012-10, Vol.53 (10), p.2017-2023

2012

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Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats

PloS one, 2010-04, Vol.5 (4), p.e9974

2010

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Functionally Overlapping Roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the Elimination of Methotrexate and Its Main Toxic Metabolite 7-Hydroxymethotrexate In vivo

Clinical cancer research, 2009-05, Vol.15 (9), p.3084-3093

2009

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NTCP deficiency in mice protects against obesity and hepatosteatosis

JCI insight, 2019-07, Vol.5 (14)

2019

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Oral availability of cefadroxil depends on ABCC3 and ABCC4

Drug metabolism and disposition, 2012-03, Vol.40 (3), p.515

2012

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Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition

The FASEB journal, 2021-02, Vol.35 (2), p.e21219-n/a

2021

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Long-Term Effects of Biliverdin Reductase a Deficiency in Ugt1 -/- Mice: Impact on Redox Status and Metabolism

Antioxidants, 2021-12, Vol.10 (12), p.2029

2021

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Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn's disease

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

Reduced spontaneous itch in mouse models of cholestasis

Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human Cholangiocytes

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1−/−Ldlr−/− mice

Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice

Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs

Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients

Adeno-associated viral vector serotype 5 poorly transduces liver in rat models

The transcriptomic signature of fasting murine liver

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning

ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein

Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein

Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats

Functionally Overlapping Roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the Elimination of Methotrexate and Its Main Toxic Metabolite 7-Hydroxymethotrexate In vivo

NTCP deficiency in mice protects against obesity and hepatosteatosis

Oral availability of cefadroxil depends on ABCC3 and ABCC4

Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition

Long-Term Effects of Biliverdin Reductase a Deficiency in Ugt1 -/- Mice: Impact on Redox Status and Metabolism

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